Prof. Kiviniemi is neuroradiologist and a pioneering fMRI researcher in Europe on the field of spontaneous brain activity fluctuations. Prof. Kiviniei introduced the now wideliy used concept of independent component analysis (ICA) into the field of (rs)fMRI. Then he focussed on intensive multimodal, ultra fast imaging assessments, also known as hexa- or hepta scanning.
During the last years his work has extended from slow neuronal connectivity fluctuations towards physiological brain pulsations. Using ultrafast 10 Hz whole brain fMRI BOLD his group has detected strong cardiorespiratory pulsations in addition to very low frequency fluctuations of the human brain. These pulsations have been shown to be a driving force of the brain clearance mechanism called the glymphatic system. During his talk Kiviniemi will show significant changes of the pulsations induced by sleep, epilepsy, and Alzheimer’s disease. In his presentation he will also cover a novel DC-EEG method to image therapeutic blood brain barrier opening with intra-arterial mannitol in neurooncological treatment of primary CNS lymphoma.