Ernst T, La Rosée P, Müller MC, Hochhaus A. BCR-ABL mutations in chronic myeloid leukemia. Hematol Oncol Clin North Am. 2011;25(5):997-vi. doi:10.1016/j.hoc.2011.09.005, PMID: 22054731

Hochhaus A: Chronic myeloid leukemia. Dtsch Med Wochenschr 2011; 136(40): 2007-2010, 136: 2007–2010 · © Georg, Thieme Verlag KG Stuttgart, New York ISSN 0012-0472; DOI: 10.1055/s-0031-1286381, 

Bacher, Ulrike; Haferlach, Torsten; Alpermann, Tamara; Zenger, Melanie; Hochhaus, Andreas; Beelen, Dietrich W. et al.: Subclones with the t(9;22)/BCR-ABL1 rearrangement occur in AML and seem to cooperate with distinct genetic alterations. Br. J. Haematol 152 (6), 713-720. PMID: 21275954

Cortes, Jorge E.; Hochhaus, Andreas; Hughes, Timothy; Kantarjian, Hagop: Front-line and salvage therapies with tyrosine kinase inhibitors and other treatments in chronic myeloid leukemia. J. Clin. Oncol 29 (5), 524-531. PMID: 21220597

Cortes, Jorge E.; Hochhaus, Andreas; Le Coutre, Philipp D.; Rosti, Gianantonio; Pinilla-Ibarz, Javier; Jabbour, Elias et al.: Minimal cross-intolerance with nilotinib in patients with chronic myeloid leukemia in chronic or accelerated phase who are intolerant to imatinib. Blood 117 (21), 5600-5606. PMID: 21467546

Elling, Christian; Erben, Philipp; Walz, Christoph; Frickenhaus, Marie; Schemionek, Mirle; Stehling, Martin et al.: Novel imatinib-sensitive PDGFRA-activating point mutations in hypereosinophilic syndrome induce growth factor independence and leukemia-like disease. Blood 117 (10), 2935-2943. PMID: 21224473

Ernst, Thomas; La Rosée, Paul; Müller, Martin C.; Hochhaus, Andreas: BCR-ABL Mutations in Chronic Myeloid Leukemia. Hematol. Oncol. Clin. North Am. 25 (5), 997-1008

Fabarius, Alice; Leitner, Armin; Hochhaus, Andreas; Müller, Martin C.; Hanfstein, Benjamin; Haferlach, Claudia et al.: Impact of ACA at diagnosis on prognosis of CML: long term observation from 1151 patients of the randomized CML Study IV. Blood PMID: 22039253

Gencer, Deniz; Tauchert, Felix; Keilhauer, Nina; Al-Batran, Salah-Eddin; Stahl, Michael; Oskay-Özcelik, Gülten et al.: Cancer Patients and the Internet: A Survey of the 'Quality of Life' Working Groups of the Arbeitsgemeinschaft für Internistische Onkologie and the Nord-Ostdeutsche Gesellschaft für Gynäkologische Onkologie. Onkologie 34 (8-9), 435-440. PMID: 21934343

Gerth, Jens; Sachse, Anja; Busch, Martin; Illner, Nico; Muegge, Lars-Olof; Gröne, Hermann-Josef; Wolf, Gunter: Screening and Differential Diagnosis of Renal Light Chain-Associated Diseases. Kidney & Blood Pressure Research. PMID: 22056791

Giles, Francis J.; Kantarjian, Hagop M.;le Coutre, Philipd D.; Baccarani, Michele; Mahon, François-Xavier; Blakesley, Rick; Gallagher, Neil J.; Gillis, Karen; Goldberg, Stuart L.; Larson, Richard A.; Hochhaus, Andreas; Ottmann, Oliver G.: Nilotinib is effective in imatinib-resistant or -intolerant patients with chronic myeloid leukemia in blastic phase. Leukemia. PMID: 22157807              

Guglielmelli, Paola; Biamonte, Flavia; Score, Joannah; Hidalgo-Curtis, Claire; Cervantes, Francisco; Maffioli, Margherita et al.: EZH2 mutational status predicts poor survival in myelofibrosis. Blood 118 (19), 5227-5234. PMID: 21921040

Härtel, Nicolai; Klag, Thomas; Hanfstein, Benjamin; Mueller, Martin C.; Schenk, Thomas; Erben, Philipp; Hochhaus, Andreas; La Rosée, Paul: Enhanced ABL-inhibitor-induced MAPK-activation in T315I-BCR-ABL-expressing cells: a potential mechanism of altered leukemogenicity. J. Cancer Res. Clin. Oncol. PMID: 22089930

Hammerman, Peter S.; Sos L. Martin; Ramos, Alex H.; Xu, Chunxiao; Dutt, Amit; Zhou, Wenjun; Brace, Lear E. et al: Mutations in the DDR2 Kinase Gene Identify a Novel Therapeutic Target in Squamous Cell Lung Cancer. Cancer Discovery, June 2011, 78-89. PMID: 22328973

Hanfstein, Benjamin; Müller, Martin C.; Kreil, Sebastian; Ernst, Thomas; Schenk, Thomas; Lorentz, Christian et al.: Dynamics of mutant BCR-ABL-positive clones after cessation of tyrosine kinase inhibitor therapy. Haematologica 96 (3), 360-366. PMID: 21134983

Kantarjian, Hagop M.; Shah, Neil P.; Cortes, Jorge E.; Baccarani, Michele; Agarwal, Mohan B.; Undurraga, María Soledad; Wang, Jianxiang; Kassack Ipiña, Juan Julio; Kim, Dong-Wook; Ogura, Michinori; Pavlovsky, Carolina; Junghanss, Christian; Milone, Jorge H.; Nicolini, Franck E.; Robak, Tadeusz; Van Droogenbroeck, Jan; Vellenga, Edo; Bradley-Garelik, M. Brigid; Zhu, Chao; Hochhaus, Andreas: Dasatinib or imatinib in newly diagnosed chronic phase chronic myeloid leukemia: 2-year follow-up from a randomized phase 3 trial (DASISION). Blood, 2011. PMID: 22160483

Hehlmann, Rüdiger; Grimwade, David; Simonsson, Bengt; Apperley, Jane; Baccarani, Michele; Barbui, Tiziano et al.: The European LeukemiaNet: achievements and perspectives. Haematologica 96 (1), 156-162. PMID: 21048032              

Hehlmann, Rüdiger; Lauseker, Michael; Jung-Munkwitz, Susanne; Leitner, Armin; Müller, Martin C.; Pletsch, Nadine et al.: Tolerability-adapted imatinib 800 mg/d versus 400 mg/d versus 400 mg/d plus interferon-α in newly diagnosed chronic myeloid leukemia. J. Clin. Oncol 29 (12), 1634-1642. PMID: 21422420

Hochhaus, Andreas: Chronische myeloische Leukämie. Dtsch. Med. Wochenschr 136 (40), 2007-2010.

Hochhaus, Andreas: Educational Session: Managing Chronic Myeloid Leukemia as a Chronic Disease. Hematology Am Soc Hematol Educ Program, 2011, 128-135. PMID: 22160024

Hochhaus, Andreas: Management of newly diagnosed chronic myeloid leukemia patients  Hematology Education. The education programme for the annual congress of the EHA, Bd.5, 120-126.

Hochhaus, Andreas; La Rosée, Paul; Müller, Martin C.; Ernst, Thomas; Cross, Nicholas C. P.: Impact of BCR-ABL mutations on patients with chronic myeloid leukemia. Cell Cycle 10 (2), 250-260. PMID: 21220945

Hurtz, Christian; Hatzi, Katerina; Cerchietti, Leandro; Braig, Melanie; Park, Eugene; Kim, Yong-Mi et al.: BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia. The Journal of Experimental Medicine 208 (11), 2163-2174. PMID: 21911423

Jabbour, Elias; Deininger, Michael; Hochhaus, Andreas: Management of adverse events associated with tyrosine kinase inhibitors in the treatment of chronic myeloid leukemia. Leukemia 25 (2), 201-210. PMID: 30587215

Kantarjian, Hagop M.; Giles, Francis J.; Bhalla, Kapil N.; Pinilla-Ibarz, Javier; Larson, Richard A.; Gattermann, Norbert et al.: Nilotinib is effective in patients with chronic myeloid leukemia in chronic phase after imatinib resistance or intolerance: 24-month follow-up results. Blood 117 (4), 1141-1145. PMID: 21098399

Kantarjian, Hagop M.; Hochhaus, Andreas; Saglio, Giuseppe; Souza, Carmino de; Flinn, Ian W.; Stenke, Leif et al.: Nilotinib versus imatinib for the treatment of patients with newly diagnosed chronic phase, Philadelphia chromosome-positive, chronic myeloid leukaemia: 24-month minimum follow-up of the phase 3 randomised ENESTnd trial. Lancet Oncol 12 (9), 841-851. PMID: 21856226

La Rosée, Paul: Tyrosinkinaseinhibitoren "-nibs".  Der Onkologe, Bd.7, S. 641-649.

Larson, Richard A.; Yin, Ophelia Q. P.;  Hochhaus, Andreas; Saglio, Giuseppe; Clark, Richard E.; Nakamae, Hirohisa; Gallagher, Neil J.; Demirhan, Eren; Hughes, Timothy P.; Kantarjian, Hagop M.; le Coutre, Philipp D.: Population pharmacokinetic and exposure-response analysis of nilotinib in patients with newly diagnosed Ph+ chronic myeloid leukemia in chronic phase. Eur J Clin Pharmacol PMID: 22207416

Leitner, Armin A.; Hochhaus, Andreas; Müller, Martin C.: Current treatment concepts of CML. Curr Cancer Drug Targets 11 (1), 31-43. PMID: 21062245              

Mügge, Lars-Olof; Schüler, Aurelian; Hochhaus, Andreas: Therapy of brain metastases and neoplastic meningitis. Onkologe (17/4), 292 ff.

Nguyen, Xuan Duc; La Rosée, Paul; Nebe, Thomas; Klüter, Harald; Buchheidt, Dieter: Rapid Treatment of Leukostasis in Leukemic Mantle Cell Lymphoma using Therapeutic Leukapheresis. A Case Report. The Scientific World Journal, Bd.11, 1554-1559. PMID: 22224069

Nicolini, Franck Emmanuel; Basak, Grzegorz W.; Soverini, Simona; Martinelli, Giovanni; Mauro, Michael J.; Müller, Martin C. et al.: Allogeneic stem cell transplantation for patients harboring T315I BCR-ABL mutated leukemias. Blood 118, 5697-5700 PMID: 21926354             

Pachmann, Katharina: Tumor Cell Seeding During Surgery. Possible Contribution to Metastasis Formations. Cancers (3), 2540-2553. PMID: 24212822

Pachmann, Katharina; Camara, Oumar; Kroll, Torsten; Gajda, Mieczyslaw; Gellner, A. K.; Wotschadlo, Jana; Runnebaum, Ingo B.: Efficacy control of therapy using circulating epithelial tumor cells (CETC) as "liquid biopsy": trastuzumab in HER2/neu-positive breast carcinoma. J. Cancer Res. Clin. Oncol 137 (9), 1317-1327. PMID: 21739182              

Pachmann, Katharina; Camara, Oumar; Kohlhase, Annika; Rabenstein, Carola; Kroll, Torsten; Runnebaum, Ingo B.; Hoeffken, Klaus: Assessing the efficacy of targeted therapy using circulating epithelial tumor cells (CETC): the example of SERM therapy monitoring as a unique tool to individualize therapy. J. Cancer Res. Clin. Oncol 137 (5), 821-828. PMID: 20694797 

Pachmann, Ulrich A.; Hekimian, Katya; Carl, Stephanie; Rüdiger, Nadine; Rabenstein, Carola; Pachmann, Katharina: Comparing Sequential Steps For Detection Of Circulating Tumor Cells: More Specific Or Just Less Sensitive? WebmedCentral Cancer (2(2)), WMC001490.

Pfirrmann, Markus; Hochhaus, Andreas; Lauseker, Michael; Saussele, Susanne; Hehlmann, Rüdiger; Hasford, Joerg: Recommendations to meet statistical challenges arising from endpoints beyond overall survival in clinical trials on chronic myeloid leukemia. Leukemia 25 (9), 1433-1438. PMID: 21597465              

Ritter, Ellen; Husain, Ralf A.; Hinderhofer, Katrin; Prell, Tino; Fricke, Hans-Jörg; Scholl, Sebastian et al.: Ornithine transcarbamylase (OTC) deficiency based on a hemizygous p.R277W mutation causing life-threatening hyperammonemic crisis during treatment for Hodgkin's lymphoma. Ann. Hematol. PMID: 21061009

Rommeley, Maraike; Spies-Weisshart, Baerbel; Schilling, Kristina; Hochhaus, Andreas; Sayer, Herbert G.; Scholl, Sebastian: Reconstitution and functional analyses of neutrophils and distinct subsets of monocytes after allogeneic stem cell transplantation. J. Cancer Res. Clin. Oncol 137 (9), 1293-1300. PMID: 21713449

Schmidt, Thomas; Kharabi Masouleh, Behzad; Loges, Sonja; Cauwenberghs, Sandra; Fraisl, Peter; Maes, Christa et al.: Loss or inhibition of stromal-derived PlGF prolongs survival of mice with imatinib-resistant Bcr-Abl1(+) leukemia. Cancer Cell 19 (6), 740-753. PMID: 31935370              

Schnetzke, Ulf; Bossert, Theo; Scholl, Sebastian; Freesmeyer, Martin; Hochhaus, Andreas; La Rosée, Paul: Drug-induced lymphadenopathy with eosinophilia and renal failure mimicking lymphoma disease: dramatic onset of DRESS syndrome associated with antibiotic treatment. Ann. Hematol 90 (11), 1353-1355. PMID: 21298267

Scholl, Sebastian; Spies-Weisshart, Baerbel; Klink, Anne; Muegge, Lars-Olof; Fricke, Hans-Joerg; Hochhaus, Andreas: Secondary resistance to sorafenib in two patients with acute myeloid leukemia (AML) harboring FLT3-ITD mutations. Ann. Hematol 90 (4), 473-475. PMID: 20652568

Soverini, Simona; Score, Joannah; Iacobucci, Ilaria; Poerio, Angela; Lonetti, Annalisa; Gnani, Alessandra et al.: IDH2 somatic mutations in chronic myeloid leukemia patients in blast crisis. Leukemia 25 (1), 178-181. PMID: 20962862

Soverini, Simona; Hochhaus, Andreas; Nicolini, Franck E.; Gruber, Franz; Lange, Thoralf; Saglio, Giuseppe et al.: BCR-ABL kinase domain mutation analysis in chronic myeloid leukemia patients treated with tyrosine kinase inhibitors: recommendations from an expert panel on behalf of European LeukemiaNet. Blood 118 (5), 1208-1215. PMID: 21562040             

Spolverini, Ambra; Jones, Amy V.; Hochhaus, Andreas; Pieri, Lisa; Cross, Nicholas C. P.; Vannucchi, Alessandro M.: The myeloproliferative neoplasm-associated JAK2 46/1 haplotype is not overrepresented in chronic myelogenous leukemia. Ann. Hematol 90 (3), 365-366. PMID: 20556390             

Stein, Andrew M.; Bottino, Dean; Modur, Vijay; Branford, Susan; Kaeda, Jaspal S.; Goldman, John et al.: BCR-ABL transcript dynamics support the hypothesis that leukemic stem cells are reduced during imatinib treatment. Clinical cancer research : an official journal of the American Association for Cancer Research. PMID: 21903771             

Walz, Christoph; Erben, Philipp; Ritter, Michael; Bloor, Adrian; Metzgeroth, Georgia; Telford, Nick et al.: Response of ETV6-FLT3-positive myeloid/lymphoid neoplasm with eosinophilia to inhibitors of FMS-like tyrosine kinase 3. Blood 118 (8), 2239-2242. PMID: 21705501

Winkelmann, Nils; Petersen, Iver; Kiehntopf, Michael; Fricke, Hans Joerg; Hochhaus, Andreas; Wedding, Ulrich: Results of comprehensive geriatric assessment effect survival in patients with malignant lymphoma. J. Cancer Res. Clin. Oncol 137 (4), 733-738. PMID: 20602238