Publikationen
Stand: 03/2024
Publikationen 2024
1: Xu F, Dirsch O, Dahmen U. Causal Relationship between Angina and Hepatic Failure as Revealed by Mendelian Randomization. J Clin Med. 2024 Jan 13;13(2):449. doi: 10.3390/jcm13020449. PMID: 38256583; PMCID: PMC10816156.
2: Xu F, Dirsch O, Dahmen U. Causal relationship between psychological factors and hepatocellular carcinoma as revealed by Mendelian randomization. J Cancer Res Clin Oncol. 2024 Feb 21;150(2):100. doi: 10.1007/s00432-024-05617-5. PMID: 38383696; PMCID: PMC10881603.
3: Lambers L, Waschinsky N, Schleicher J, König M, Tautenhahn HM, Albadry M, Dahmen U, Ricken T. Quantifying fat zonation in liver lobules: an integrated multiscale in silico model combining disturbed microperfusion and fat metabolism via a continuum biomechanical bi-scale, tri-phasic approach. Biomech Model Mechanobiol. 2024 Feb 25. doi: 10.1007/s10237-023-01797-0. Epub ahead of print. PMID: 38402347.
Publikationen 2023
1: Press AT, Ungelenk L, Medyukhina A, Pennington SA, Nietzsche S, Kan C, Lupp A, Dahmen U, Wang R, Settmacher U, Wetzker R, Figge MT, Clemens MG, Bauer M. Sodium thiosulfate refuels the hepatic antioxidant pool reducing ischemia- reperfusion-induced liver injury. Free Radic Biol Med. 2023 Aug 1;204:151-160. doi: 10.1016/j.freeradbiomed.2023.04.012. Epub 2023 Apr 25. PMID: 37105418.
2: Chen H, Dirsch O, Albadry M, Ana PH, Dahmen U. Normothermic Ex Vivo Liver Machine Perfusion in Mouse. J Vis Exp. 2023 Sep 25;(199). doi: 10.3791/65363. PMID: 37811934.
3: Luo D, Chen X, Du J, Mei B, Wang A, Kuang F, Fang C, Gan Y, Peng F, Yang X, Dahmen U, Li B, Song S. Immunogenicity of COVID-19 vaccines in chronic liver disease patients and liver transplant recipients: A systematic review and meta- analysis. Liver Int. 2023 Jan;43(1):34-48. doi: 10.1111/liv.15403. Epub 2022 Sep 14. PMID: 35986903; PMCID: PMC9537964.
Publikationen 2022
1: Christ B, Dahmen U, Radde N, Ricken T. Editorial: Computational Modeling for Liver Surgery and Interventions. Front Physiol. 2022 Feb 15;13:859522. doi: 10.3389/fphys.2022.859522. PMID: 35242057; PMCID: PMC8886156.
2: Albadry M, Höpfl S, Ehteshamzad N, König M, Böttcher M, Neumann J, Lupp A, Dirsch O, Radde N, Christ B, Christ M, Schwen LO, Laue H, Klopfleisch R, Dahmen U. Periportal steatosis in mice affects distinct parameters of pericentral drug metabolism. Sci Rep. 2022 Dec 17;12(1):21825. doi: 10.1038/s41598-022-26483-6. PMID: 36528753; PMCID: PMC9759570.
3: Luo D, Chen X, Du J, Mei B, Wang A, Kuang F, Fang C, Gan Y, Peng F, Yang X, Dahmen U, Li B, Song S. Immunogenicity of COVID-19 vaccines in chronic liver disease patients and liver transplant recipients: A systematic review and meta- analysis. Liver Int. 2023 Jan;43(1):34-48. doi: 10.1111/liv.15403. Epub 2022 Sep 14. PMID: 35986903; PMCID: PMC9537964.
4: Richter B, Sänger C, Mussbach F, Scheuerlein H, Settmacher U, Dahmen U. Selective biliary occlusion in rodents: description of a new technique. Innov Surg Sci. 2022 Jun 23;7(1):13-22. doi: 10.1515/iss-2021-0044. PMID: 35974775; PMCID: PMC9352182.
5: Massaro MS, Kochová P, Pálek R, Rosendorf J, Červenková L, Dahmen U, Liška V, Moulisová V. Decellularization of Porcine Carotid Arteries: From the Vessel to the High-Quality Scaffold in Five Hours. Front Bioeng Biotechnol. 2022 May 16;10:833244. doi: 10.3389/fbioe.2022.833244. PMID: 35651544; PMCID: PMC9150822.
6: Budelmann D, Laue H, Weiss N, Dahmen U, D'Alessandro LA, Biermayer I, Klingmüller U, Ghallab A, Hassan R, Begher-Tibbe B, Hengstler JG, Schwen LO. Automated Detection of Portal Fields and Central Veins in Whole-Slide Images of Liver Tissue. J Pathol Inform. 2022 Jan 20;13:100001. doi: 10.1016/j.jpi.2022.100001. PMID: 35242441; PMCID: PMC8860737.
7: Richter B, Sänger C, Mussbach F, Scheuerlein H, Settmacher U, Dahmen U. Species specific morphological alterations in liver tissue after biliary occlusion in rat and mouse: Similar but different. PLoS One. 2022 Jul 26;17(7):e0271975. doi: 10.1371/journal.pone.0271975. PMID: 35881613; PMCID: PMC9321426.
8: Liu A, Jin H, Dirsch O, Deng M, Huang H, Bröcker-Preuss M, Dahmen U. Corrigendum to "Release of Danger Signals during Ischemic Storage of the Liver: A Potential Marker of Organ Damage?". Mediators Inflamm. 2022 May 9;2022:9870324. doi: 10.1155/2022/9870324. Erratum for: Mediators Inflamm. 2010;2010:436145. PMID: 35586368; PMCID: PMC9110253.
9: Arlt J, Vlaic S, Feuer R, Thomas M, Settmacher U, Dahmen U, Dirsch O. Selective gene expression profiling contributes to a better understanding of the molecular pathways underlying the histological changes observed after RHMVL. BMC Med Genomics. 2022 Oct 7;15(1):211. doi: 10.1186/s12920-022-01364-z. PMID: 36207717; PMCID: PMC9547442.
10: Xu F, Tautenhahn HM, Dirsch O, Dahmen U. Blocking autophagy with chloroquine aggravates lipid accumulation and reduces intracellular energy synthesis in hepatocellular carcinoma cells, both contributing to its anti-proliferative effect. J Cancer Res Clin Oncol. 2022 Dec;148(12):3243-3256. doi: 10.1007/s00432-022-04074-2. Epub 2022 Jun 13. PMID: 35695930; PMCID: PMC9587105.
11: Richter B, Zafarnia S, Gremse F, Kießling F, Scheuerlein H, Settmacher U, Dahmen U. Corrosion Cast and 3D Reconstruction of the Murine Biliary Tree After Biliary Obstruction: Quantitative Assessment and Comparison With 2D Histology. J Clin Exp Hepatol. 2022 May-Jun;12(3):755-766. doi: 10.1016/j.jceh.2021.12.008. Epub 2021 Dec 20. PMID: 35677523; PMCID: PMC9168744.
12: Richter B, Sänger C, Mussbach F, Scheuerlein H, Settmacher U, Dahmen U. The Interplay Between Biliary Occlusion and Liver Regeneration: Repeated Regeneration Stimuli Restore Biliary Drainage by Promoting Hepatobiliary Remodeling in a Rat Model. Front Surg. 2022 Apr 25;9:799669. doi: 10.3389/fsurg.2022.799669. PMID: 35548189; PMCID: PMC9081651.
Publikationen 2021
1: Xu F, Tautenhahn HM, Dirsch O, Dahmen U. Modulation of Autophagy: A Novel "Rejuvenation" Strategy for the Aging Liver. Oxid Med Cell Longev. 2021 Feb 10;2021:6611126. doi: 10.1155/2021/6611126. PMID: 33628363; PMCID: PMC7889356.
2: Meng L, Song Z, Liu A, Dahmen U, Yang X, Fang H. Effects of Lipopolysaccharide-Binding Protein (LBP) Single Nucleotide Polymorphism (SNP) in Infections, Inflammatory Diseases, Metabolic Disorders and Cancers. Front Immunol. 2021 Jul 6;12:681810. doi: 10.3389/fimmu.2021.681810. PMID: 34295331; PMCID: PMC8290185.
3: Christ B, Collatz M, Dahmen U, Herrmann KH, Höpfl S, König M, Lambers L, Marz M, Meyer D, Radde N, Reichenbach JR, Ricken T, Tautenhahn HM. Hepatectomy- Induced Alterations in Hepatic Perfusion and Function - Toward Multi-Scale Computational Modeling for a Better Prediction of Post-hepatectomy Liver Function. Front Physiol. 2021 Nov 18;12:733868. doi: 10.3389/fphys.2021.733868. PMID: 34867441; PMCID: PMC8637208.
4: Felgendreff P, Schindler C, Mussbach F, Xie C, Gremse F, Settmacher U, Dahmen U. Identification of tissue sections from decellularized liver scaffolds for repopulation experiments. Heliyon. 2021 Feb 13;7(2):e06129. doi: 10.1016/j.heliyon.2021.e06129. PMID: 33644446; PMCID: PMC7895725.
5: Daum AK, Dittmann J, Jansen L, Peters S, Dahmen U, Heger JI, Hoppe-Seyler F, Gille A, Clement JH, Runnebaum IB, Dürst M, Backsch C. ITIH5 shows tumor suppressive properties in cervical cancer cells grown as multicellular tumor spheroids. Am J Transl Res. 2021 Sep 15;13(9):10298-10314. PMID: 34650698; PMCID: PMC8507072.
6: Hua C, Wei W, Zhang T, Xu F, Dirsch O, Homeyer A, Settmacher U, Dahmen U. Additional partial hepatectomy at the time of portal vein ligation accelerates the regeneration of the future liver remnant. Sci Rep. 2021 Jun 3;11(1):11740. doi: 10.1038/s41598-021-90819-x. PMID: 34083554; PMCID: PMC8175446.
7: Richter B, Zafarnia S, Gremse F, Kießling F, Scheuerlein H, Settmacher U, Dahmen U. Corrosion Cast and 3D Reconstruction of the Murine Biliary Tree After Biliary Obstruction: Quantitative Assessment and Comparison With 2D Histology. J Clin Exp Hepatol. 2022 May-Jun;12(3):755-766. doi: 10.1016/j.jceh.2021.12.008. Epub 2021 Dec 20. PMID: 35677523; PMCID: PMC9168744.
Publikationen 2020
1: Xu F, Hua C, Tautenhahn HM, Dirsch O, Dahmen U. The Role of Autophagy for the Regeneration of the Aging Liver. Int J Mol Sci. 2020 May 20;21(10):3606. doi: 10.3390/ijms21103606. PMID: 32443776; PMCID: PMC7279469.
2: Ho H, Dahmen U, Hunter P. An in silico rat liver atlas. Comput Methods Biomech Biomed Engin. 2020 Aug;23(10):597-600. doi: 10.1080/10255842.2020.1754404. Epub 2020 Apr 20. PMID: 32310673.
3: Meyer K, Morales-Navarrete H, Seifert S, Wilsch-Braeuninger M, Dahmen U, Tanaka EM, Brusch L, Kalaidzidis Y, Zerial M. Bile canaliculi remodeling activates YAP via the actin cytoskeleton during liver regeneration. Mol Syst Biol. 2020 Feb;16(2):e8985. doi: 10.15252/msb.20198985. PMID: 32090478; PMCID: PMC7036714.
4: Jirik M, Gruber I, Moulisova V, Schindler C, Cervenkova L, Palek R, Rosendorf J, Arlt J, Bolek L, Dejmek J, Dahmen U, Zelezny M, Liska V. Semantic Segmentation of Intralobular and Extralobular Tissue from Liver Scaffold H&E Images. Sensors (Basel). 2020 Dec 10;20(24):7063. doi: 10.3390/s20247063. PMID: 33321713; PMCID: PMC7764590.
5: Moulisová V, Jiřík M, Schindler C, Červenková L, Pálek R, Rosendorf J, Arlt J, Bolek L, Šůsová S, Nietzsche S, Liška V, Dahmen U. Novel morphological multi- scale evaluation system for quality assessment of decellularized liver scaffolds. J Tissue Eng. 2020 May 27;11:2041731420921121. doi: 10.1177/2041731420921121. PMID: 32523667; PMCID: PMC7257850.
6: Wang A, Kuriata O, Xu F, Nietzsche S, Gremse F, Dirsch O, Settmacher U, Dahmen U. A Survival Model of In Vivo Partial Liver Lobe Decellularization Towards In Vivo Liver Engineering. Tissue Eng Part C Methods. 2020 Aug;26(8):402-417. doi: 10.1089/ten.TEC.2019.0194. Epub 2019 Dec 26. PMID: 31668131.
7: Bachmann C, Paz Hernandez AL, Müller S, Khalatbarizamanpoor S, Tschiesche T, Reißmann F, Kiesow L, Ebbert D, Smirnow W, Wilken A, Dahmen U. Digital teaching and learning of surgical skills (not only) during the pandemic: a report on a blended learning project. GMS J Med Educ. 2020 Dec 3;37(7):Doc68. doi: 10.3205/zma001361. PMID: 33364347; PMCID: PMC7740016.
8: Wei W, Hua C, Zhang T, Dirsch O, Gremse F, Homeyer A, Settmacher U, Dahmen U. Size of portally deprived liver lobe after portal vein ligation and additional partial hepatectomy: Result of balancing proliferation and apoptosis. Sci Rep. 2020 Mar 17;10(1):4893. doi: 10.1038/s41598-020-60310-0. PMID: 32184404; PMCID: PMC7078252.
9: Werner C, Dirsch O, Dahmen U, Grimm MO, Schulz S, Lupp A. Evaluation of Somatostatin and CXCR4 Receptor Expression in a Large Set of Prostate Cancer Samples Using Tissue Microarrays and Well-Characterized Monoclonal Antibodies. Transl Oncol. 2020 Sep;13(9):100801. doi: 10.1016/j.tranon.2020.100801. Epub 2020 May 24. PMID: 32460182; PMCID: PMC7249232.
Publikationen 2019
1: Müller S, Koch I, Settmacher U, Dahmen U. How the introduction of OSCEs has affected the time students spend studying: results of a nationwide study. BMC Med Educ. 2019 May 15;19(1):146. doi: 10.1186/s12909-019-1570-6. PubMed PMID:
31092236; PubMed Central PMCID: PMC6521539.
2: Adili F, Dahmen U, Heinemann MK, Kadmon M, Kauffels-Sprenger A, König S, Meder A, Obertacke U, Schwanitz von Keitz P, Stefanescu C, Sterz J, Rüsseler M. [Position Paper of the Surgical Working Group for Teaching of the German Society
of Surgery Regarding the "Master Plan 2020"]. Zentralbl Chir. 2019 May 8. doi: 10.1055/a-0869-8081. [Epub ahead of print] German. PubMed PMID: 31067573.
3: Kan C, Liu A, Fang H, Dirsch O, Dahmen U, Böettcher M. Corrigendum to Induction of Autophagy Reduces Ischemia/Reperfusion Injury in Steatotic Rat Livers [Journal of Surgical Research 216 (2017) 207-218]. J Surg Res. 2019
May;237:138. doi: 10.1016/j.jss.2017.11.040. Epub 2018 Jan 3. PubMed PMID: 29306480.
4: Rauchfuß F, Helble J, Bruns J, Dirsch O, Dahmen U, Ardelt M, Settmacher U, Scheuerlein H. Biocellulose for Incisional Hernia Repair-An Experimental Pilot Study. Nanomaterials (Basel). 2019 Feb 10;9(2). pii: E236. doi: 10.3390/nano9020236. PubMed PMID: 30744160; PubMed Central PMCID: PMC6410132.
5: Liu A, Yang J, Hu Q, Dirsch O, Dahmen U, Zhang C, Gewirtz DA, Fang H, Sun J. Young plasma attenuates age-dependent liver ischemia reperfusion injury. FASEB J. 2019 Feb;33(2):3063-3073. doi: 10.1096/fj.201801234R. Epub 2018 Nov 1. PubMed
PMID: 30383439.
Publikationen 2018
1: Kan C, Liu A, Fang H, Dirsch O, Dahmen U, Böettcher M. Corrigendum to Induction of Autophagy Reduces Ischemia/Reperfusion Injury in Steatotic Rat Livers [Journal of Surgical Research 216 (2017) 207-218]. J Surg Res. 2019
May;237:138. doi: 10.1016/j.jss.2017.11.040. Epub 2018 Jan 3. PubMed PMID: 29306480.
2: Liu A, Yang J, Hu Q, Dirsch O, Dahmen U, Zhang C, Gewirtz DA, Fang H, Sun J. Young plasma attenuates age-dependent liver ischemia reperfusion injury. FASEB J. 2019 Feb;33(2):3063-3073. doi: 10.1096/fj.201801234R. Epub 2018 Nov 1. PubMed
PMID: 30383439.
3: Müller S, Settmacher U, Koch I, Dahmen U. A pilot survey of student perceptions on the benefit of the OSCE and MCQ modalities. GMS J Med Educ. 2018 Nov 15;35(4):Doc51. doi: 10.3205/zma001197. eCollection 2018. PubMed PMID: 30539076; PubMed Central PMCID: PMC6278234.
4: Fang H, Liu A, Chen X, Cheng W, Dirsch O, Dahmen U. The severity of LPS induced inflammatory injury is negatively associated with the functional liver mass after LPS injection in rat model. J Inflamm (Lond). 2018 Nov 15;15:21. doi: 10.1186/s12950-018-0197-4. eCollection 2018. PubMed PMID: 30473633; PubMed Central PMCID: PMC6238277.
5: Fang H, Hua C, Weiss S, Liu A, Cheng W, Claus R, Rödel J, Dirsch O, Dahmen U. Modulation of Innate Immunity by G-CSF and Inflammatory Response by LBPK95A Improves the Outcome of Sepsis in a Rat Model. J Immunol Res. 2018 Nov
7;2018:6085095. doi: 10.1155/2018/6085095. eCollection 2018. PubMed PMID: 30525057; PubMed Central PMCID: PMC6247567.
6: Schleicher J, Dahmen U. Computational Modeling of Oxidative Stress in Fatty Livers Elucidates the Underlying Mechanism of the Increased Susceptibility to Ischemia/Reperfusion Injury. Comput Struct Biotechnol J. 2018 Nov 1;16:511-522. doi: 10.1016/j.csbj.2018.10.013. eCollection 2018. PubMed PMID: 30505404; PubMed Central PMCID: PMC6247397.
7: Wang A, Jank I, Wei W, Schindler C, Dahmen U. A Novel Surgical Technique As a Foundation for In Vivo Partial Liver Engineering in Rat. J Vis Exp. 2018 Oct 6;(140). doi: 10.3791/57991. PubMed PMID: 30346385; PubMed Central PMCID:
PMC6235435.
8: Homeyer A, Hammad S, Schwen LO, Dahmen U, Höfener H, Gao Y, Dooley S, Schenk A. Focused scores enable reliable discrimination of small differences in steatosis. Diagn Pathol. 2018 Sep 20;13(1):76. doi: 10.1186/s13000-018-0753-5. PubMed PMID: 30231920; PubMed Central PMCID: PMC6146776.
9: Liu A, Dong W, Peng J, Dirsch O, Dahmen U, Fang H, Zhang C, Sun J. Growth differentiation factor 11 worsens hepatocellular injury and liver regeneration after liver ischemia reperfusion injury. FASEB J. 2018 Sep;32(9):5186-5198. doi: 10.1096/fj.201800195R. Epub 2018 Apr 17. PubMed PMID: 29913561.
10: Fang H, Jin H, Hua C, Liu A, Song Z, Chen X, Dirsch O, Dahmen U. The LPS Responsiveness in BN and LEW Rats and Its Severity Are Modulated by the Liver. J Immunol Res. 2018 Jul 30;2018:6328713. doi: 10.1155/2018/6328713. eCollection
2018. PubMed PMID: 30151394; PubMed Central PMCID: PMC6091288.
11: Grasreiner D, Dahmen U, Settmacher U. Specialty preferences and influencing factors: a repeated cross-sectional survey of first- to sixth-year medical students in Jena, Germany. BMC Med Educ. 2018 May 9;18(1):103. doi: 10.1186/s12909-018-1200-8. PubMed PMID: 29743057; PubMed Central PMCID: PMC5944057.
12: Tekbas A, Huebner J, Settmacher U, Dahmen U. Plants and Surgery: The Protective Effects of Thymoquinone on Hepatic Injury-A Systematic Review of In Vivo Studies. Int J Mol Sci. 2018 Apr 5;19(4). pii: E1085. doi: 10.3390/ijms19041085. Review. PubMed PMID: 29621129; PubMed Central PMCID: PMC5979411.
13: Kan C, Ungelenk L, Lupp A, Dirsch O, Dahmen U. Ischemia-Reperfusion Injury in Aged Livers-The Energy Metabolism, Inflammatory Response, and Autophagy. Transplantation. 2018 Mar;102(3):368-377. doi: 10.1097/TP.0000000000001999.
Review. PubMed PMID: 29135887.
14: Liu A, Guo E, Yang J, Yang Y, Liu S, Jiang X, Hu Q, Dirsch O, Dahmen U, Zhang C, Gewirtz DA, Fang H. Young plasma reverses age-dependent alterations in hepatic function through the restoration of autophagy. Aging Cell. 2018 Feb;17(1). doi:
10.1111/acel.12708. Epub 2017 Dec 5. PubMed PMID: 29210183; PubMed Central PMCID: PMC5770779.
15: Vlaic S, Conrad T, Tokarski-Schnelle C, Gustafsson M, Dahmen U, Guthke R, Schuster S. ModuleDiscoverer: Identification of regulatory modules in protein-protein interaction networks. Sci Rep. 2018 Jan 11;8(1):433. doi: 10.1038/s41598-017-18370-2. PubMed PMID: 29323246; PubMed Central PMCID: PMC5764996.
Publikationen 2017
1: Kan C, Liu A, Fang H, Dirsch O, Dahmen U, Böettcher M. Corrigendum to Induction of Autophagy Reduces Ischemia/Reperfusion Injury in Steatotic Rat Livers [Journal of Surgical Research 216 (2017) 207-218]. J Surg Res. 2019
May;237:138. doi: 10.1016/j.jss.2017.11.040. Epub 2018 Jan 3. PubMed PMID: 29306480.
2: Liu A, Guo E, Yang J, Yang Y, Liu S, Jiang X, Hu Q, Dirsch O, Dahmen U, Zhang C, Gewirtz DA, Fang H. Young plasma reverses age-dependent alterations in hepatic function through the restoration of autophagy. Aging Cell. 2018 Feb;17(1). doi:
10.1111/acel.12708. Epub 2017 Dec 5. PubMed PMID: 29210183; PubMed Central PMCID: PMC5770779.
3: Kaemmerer D, Schindler R, Mußbach F, Dahmen U, Altendorf-Hofmann A, Dirsch O, Sänger J, Schulz S, Lupp A. Somatostatin and CXCR4 chemokine receptor expression in hepatocellular and cholangiocellular carcinomas: tumor capillaries as promising targets. BMC Cancer. 2017 Dec 28;17(1):896. doi: 10.1186/s12885-017-3911-3. PubMed PMID: 29282035; PubMed Central PMCID: PMC5745780.
4: Christ B, Dahmen U, Herrmann KH, König M, Reichenbach JR, Ricken T, Schleicher J, Ole Schwen L, Vlaic S, Waschinsky N. Computational Modeling in Liver Surgery. Front Physiol. 2017 Nov 14;8:906. doi: 10.3389/fphys.2017.00906. eCollection
2017. Review. PubMed PMID: 29249974; PubMed Central PMCID: PMC5715340.
5: Schleicher J, Dahmen U, Guthke R, Schuster S. Zonation of hepatic fat accumulation: insights from mathematical modelling of nutrient gradients and fatty acid uptake. J R Soc Interface. 2017 Aug;14(133). pii: 20170443. doi: 10.1098/rsif.2017.0443. PubMed PMID: 28835543; PubMed Central PMCID: PMC5582132.
6: Kan C, Liu A, Fang H, Dirsch O, Dahmen U, Boettcher M. Induction of autophagy reduces ischemia/reperfusion injury in steatotic rat livers. J Surg Res. 2017 Aug;216:207-218. doi: 10.1016/j.jss.2017.04.012. Epub 2017 Apr 20. Erratum in: J
Surg Res. 2018 Jan 3;:. PubMed PMID: 28807209.
7: Dondorf F, Fahrner R, Ardelt M, Patsenker E, Stickel F, Dahmen U, Settmacher U, Rauchfuß F. Induction of chronic cholestasis without liver cirrhosis - Creation of an animal model. World J Gastroenterol. 2017 Jun 21;23(23):4191-4199.
doi: 10.3748/wjg.v23.i23.4191. PubMed PMID: 28694659; PubMed Central PMCID: PMC5483493.
8: Sun J, Guo E, Yang J, Yang Y, Liu S, Hu J, Jiang X, Dirsch O, Dahmen U, Dong W, Liu A. Carbon monoxide ameliorates hepatic ischemia/reperfusion injury via sirtuin 1-mediated deacetylation of high-mobility group box 1 in rats. Liver Transpl. 2017 Apr;23(4):510-526. doi: 10.1002/lt.24733. PubMed PMID: 28133883.
9: Zhang T, Wei W, Dirsch O, Krüger T, Kan C, Xie C, Kniemeyer O, Fang H, Settmacher U, Dahmen U. Identification of Proteins Interacting with Cytoplasmic High-Mobility Group Box 1 during the Hepatocellular Response to Ischemia Reperfusion Injury. Int J Mol Sci. 2017 Jan 16;18(1). pii: E167. doi: 10.3390/ijms18010167. PubMed PMID: 28275217; PubMed Central PMCID: PMC5297800.
10: Tolba RH, Czigány Z, Osorio Lujan S, Oltean M, Axelsson M, Akelina Y, Di Cataldo A, Miko I, Furka I, Dahmen U, Kobayashi E, Ionac M, Nemeth N. Defining Standards in Experimental Microsurgical Training: Recommendations of the European
Society for Surgical Research (ESSR) and the International Society for Experimental Microsurgery (ISEM). Eur Surg Res. 2017;58(5-6):246-262. doi: 10.1159/000479005. Epub 2017 Jul 26. Review. PubMed PMID: 28746936.
Publikationen 2016
1: Terbonssen T, Settmacher U, Wurst C, Dirsch O, Dahmen U. Attitude towards organ donation in German medical students. Langenbecks Arch Surg. 2016 Dec;401(8):1231-1239. Epub 2016 Jul 21. PubMed PMID: 27443849.
2: Liu A, Guo E, Yang J, Li R, Yang Y, Liu S, Hu J, Jiang X, Dirsch O, Dahmen U, Sun J, Ouyang M. Ischemic preconditioning attenuates ischemia/reperfusion injury in rat steatotic liver: role of heme oxygenase-1-mediated autophagy. Oncotarget. 2016 Nov 29;7(48):78372-78386. doi: 10.18632/oncotarget.13281. PubMed PMID: 27852058; PubMed Central PMCID: PMC5346646.
3: Godoy P, Widera A, Schmidt-Heck W, Campos G, Meyer C, Cadenas C, Reif R, Stöber R, Hammad S, Pütter L, Gianmoena K, Marchan R, Ghallab A, Edlund K, Nüssler A, Thasler WE, Damm G, Seehofer D, Weiss TS, Dirsch O, Dahmen U, Gebhardt
R, Chaudhari U, Meganathan K, Sachinidis A, Kelm J, Hofmann U, Zahedi RP, Guthke R, Blüthgen N, Dooley S, Hengstler JG. Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue. Arch Toxicol. 2016 Oct;90(10):2513-29. doi: 10.1007/s00204-016-1761-4. Epub 2016 Jun 23. PubMed PMID: 27339419; PubMed Central PMCID: PMC5043005.
4: Xie C, Wei W, Schenk A, Schwen LO, Zafarnia S, Schwier M, Gremse F, Jank I, Dirsch O, Dahmen U. Visualization of Vascular and Parenchymal Regeneration after 70% Partial Hepatectomy in Normal Mice. J Vis Exp. 2016 Sep 13;(115). doi: 10.3791/53935. PubMed PMID: 27685096; PubMed Central PMCID: PMC5092013.
5: Xie C, Schwen LO, Wei W, Schenk A, Zafarnia S, Gremse F, Dahmen U. Quantification of Hepatic Vascular and Parenchymal Regeneration in Mice. PLoS One. 2016 Aug 5;11(8):e0160581. doi: 10.1371/journal.pone.0160581. eCollection 2016. PubMed PMID: 27494255; PubMed Central PMCID: PMC4975469.
6: Schwen LO, Homeyer A, Schwier M, Dahmen U, Dirsch O, Schenk A, Kuepfer L, Preusser T, Schenk A. Zonated quantification of steatosis in an entire mouse liver. Comput Biol Med. 2016 Jun 1;73:108-18. doi: 10.1016/j.compbiomed.2016.04.004. Epub 2016 Apr 11. PubMed PMID: 27104496.
7: Liu A, Huang L, Guo E, Li R, Yang J, Li A, Yang Y, Liu S, Hu J, Jiang X, Dirsch O, Dahmen U, Sun J. Baicalein pretreatment reduces liver ischemia/reperfusion injury via induction of autophagy in rats. Sci Rep. 2016 May 6;6:25042. doi: 10.1038/srep25042. PubMed PMID: 27150843; PubMed Central PMCID: PMC4858649.
8: Wei W, Zhang T, Zafarnia S, Schenk A, Xie C, Kan C, Dirsch O, Settmacher U, Dahmen U. Establishment of a rat model: Associating liver partition with portal vein ligation for staged hepatectomy. Surgery. 2016 May;159(5):1299-307. doi: 10.1016/j.surg.2015.12.005. Epub 2016 Feb 12. PubMed PMID: 26879073.
9: Dahmen U, Schulze C, Schindler C, Wick K, Schwartze D, Veit A, Smolenski U. Recommendations to enhance constructivist-based learning in Interprofessional Education using video-based self-assessment. GMS J Med Educ. 2016 Apr 29;33(2):Doc33. doi: 10.3205/zma001032. eCollection 2016. PubMed PMID: 27280144; PubMed Central PMCID: PMC4895861.
10: Vartak N, Damle-Vartak A, Richter B, Dirsch O, Dahmen U, Hammad S, Hengstler JG. Cholestasis-induced adaptive remodeling of interlobular bile ducts. Hepatology. 2016 Mar;63(3):951-64. doi: 10.1002/hep.28373. Epub 2016 Jan 14. PubMed PMID: 26610202; PubMed Central PMCID: PMC5066759.
11: Arlt J, Homeyer A, Sänger C, Dahmen U, Dirsch O. One Size Fits All: Evaluation of the Transferability of a New "Learning" Histologic Image Analysis Application. Appl Immunohistochem Mol Morphol. 2016 Jan;24(1):1-10. doi: 10.1097/PAI.0000000000000120. Review. PubMed PMID: 25517866.
12: Mußbach F, Settmacher U, Dirsch O, Xie C, Dahmen U. Bioengineered Livers: A New Tool for Drug Testing and a Promising Solution to Meet the Growing Demand for Donor Organs. Eur Surg Res. 2016;57(3-4):224-239. Epub 2016 Jul 27. Review.
PubMed PMID: 27459202.
13: Wei W, Zhang T, Fang H, Dirsch O, Schenk A, Homeyer A, Gremse F, Zafarnia S, Settmacher U, Dahmen U. Intrahepatic Size Regulation in a Surgical Model: Liver Resection-Induced Liver Regeneration Counteracts the Local Atrophy following
Simultaneous Portal Vein Ligation. Eur Surg Res. 2016;57(1-2):125-37. doi: 10.1159/000446875. Epub 2016 Jun 17. PubMed PMID: 27308828.
Publikationen 2015
1: Sänger C, Schenk A, Schwen LO, Wang L, Gremse F, Zafarnia S, Kiessling F, Xie C, Wei W, Richter B, Dirsch O, Dahmen U. Intrahepatic Vascular Anatomy in Rats and Mice--Variations and Surgical Implications. PLoS One. 2015 Nov 30;10(11):e0141798. doi: 10.1371/journal.pone.0141798. eCollection 2015. PubMed PMID: 26618494; PubMed Central PMCID: PMC4664386.
2: Homeyer A, Schenk A, Arlt J, Dahmen U, Dirsch O, Hahn HK. Fast and accurate identification of fat droplets in histological images. Comput Methods Programs Biomed. 2015 Sep;121(2):59-65. doi: 10.1016/j.cmpb.2015.05.009. Epub 2015 Jun 6.
PubMed PMID: 26093386.
3: Feuer R, Vlaic S, Arlt J, Sawodny O, Dahmen U, Zanger UM, Thomas M. LEMming: A Linear Error Model to Normalize Parallel Quantitative Real-Time PCR (qPCR) Data as an Alternative to Reference Gene Based Methods. PLoS One. 2015 Sep
1;10(9):e0135852. doi: 10.1371/journal.pone.0135852. eCollection 2015. PubMed PMID: 26325269; PubMed Central PMCID: PMC4556681.
4: Terbonssen T, Settmacher U, Wurst C, Dirsch O, Dahmen U. Effectiveness of Organ Donation Information Campaigns in Germany: A Facebook Based Online Survey. Interact J Med Res. 2015 Jul 28;4(3):e16. doi: 10.2196/ijmr.4287. PubMed PMID:
26220442; PubMed Central PMCID: PMC4705356.
5: Liu A, Weiss S, Fang H, Claus RA, Rödel J, Dirsch O, Dahmen U. Lipopolysaccharide-binding protein (LBP) blockade augments the protective effect of granulocyte colony-stimulating factor (G-CSF) in a rat sepsis model. Shock. 2015 May;43(5):497-503. doi: 10.1097/SHK.0000000000000338. PubMed PMID: 25874537.
6: Liu A, Wang W, Fang H, Yang Y, Jiang X, Liu S, Hu J, Hu Q, Dahmen U, Dirsch O. Baicalein protects against polymicrobial sepsis-induced liver injury via inhibition of inflammation and apoptosis in mice. Eur J Pharmacol. 2015 Feb 5;748:45-53. doi: 10.1016/j.ejphar.2014.12.014. Epub 2014 Dec 20. PubMed PMID: 25533331.
7: Schwen LO, Wei W, Gremse F, Ehling J, Wang L, Dahmen U, Preusser T. Algorithmically generated rodent hepatic vascular trees in arbitrary detail. J Theor Biol. 2015 Jan 21;365:289-300. doi: 10.1016/j.jtbi.2014.10.026. Epub 2014 Nov 5. PubMed PMID: 25451523.
8: Wei W, Dirsch O, Mclean AL, Zafarnia S, Schwier M, Dahmen U. Rodent models and imaging techniques to study liver regeneration. Eur Surg Res. 2015;54(3-4):97-113. doi: 10.1159/000368573. Epub 2014 Nov 12. Review. PubMed PMID: 25402256.
9: Liu A, Huang L, Fan H, Fang H, Yang Y, Liu S, Hu J, Hu Q, Dirsch O, Dahmen U. Baicalein pretreatment protects against liver ischemia/reperfusion injury via inhibition of NF-κB pathway in mice. Int Immunopharmacol. 2015 Jan;24(1):72-9. doi: 10.1016/j.intimp.2014.11.014. Epub 2014 Nov 22. PubMed PMID: 25479717.
10: Fang H, Jiang W, Cheng J, Lu Y, Liu A, Kan L, Dahmen U. Balancing Innate Immunity and Inflammatory State via Modulation of Neutrophil Function: A Novel Strategy to Fight Sepsis. J Immunol Res. 2015;2015:187048. doi: 10.1155/2015/187048. Epub 2015 Dec 21. Review. PubMed PMID: 26798659; PubMed Central PMCID: PMC4699010.
Publikationen 2014
1: Ricken T, Werner D, Holzhütter HG, König M, Dahmen U, Dirsch O. Modeling function-perfusion behavior in liver lobules including tissue, blood, glucose, lactate and glycogen by use of a coupled two-scale PDE-ODE approach. Biomech Model Mechanobiol. 2015 Jun;14(3):515-36. doi: 10.1007/s10237-014-0619-z. Epub 2014 Sep 19. PubMed PMID: 25236798.
2: Liu A, Wang W, Fang H, Yang Y, Jiang X, Liu S, Hu J, Hu Q, Dahmen U, Dirsch O. Baicalein protects against polymicrobial sepsis-induced liver injury via inhibition of inflammation and apoptosis in mice. Eur J Pharmacol. 2015 Feb 5;748:45-53. doi: 10.1016/j.ejphar.2014.12.014. Epub 2014 Dec 20. PubMed PMID: 25533331.
3: Schwen LO, Wei W, Gremse F, Ehling J, Wang L, Dahmen U, Preusser T. Algorithmically generated rodent hepatic vascular trees in arbitrary detail. J Theor Biol. 2015 Jan 21;365:289-300. doi: 10.1016/j.jtbi.2014.10.026. Epub 2014 Nov 5. PubMed PMID: 25451523.
4: Wei W, Dirsch O, Mclean AL, Zafarnia S, Schwier M, Dahmen U. Rodent models and imaging techniques to study liver regeneration. Eur Surg Res. 2015;54(3-4):97-113. doi: 10.1159/000368573. Epub 2014 Nov 12. Review. PubMed PMID: 25402256.
5: Liu A, Huang L, Fan H, Fang H, Yang Y, Liu S, Hu J, Hu Q, Dirsch O, Dahmen U. Baicalein pretreatment protects against liver ischemia/reperfusion injury via inhibition of NF-κB pathway in mice. Int Immunopharmacol. 2015 Jan;24(1):72-9. doi: 10.1016/j.intimp.2014.11.014. Epub 2014 Nov 22. PubMed PMID: 25479717.
6: Drasdo D, Bode J, Dahmen U, Dirsch O, Dooley S, Gebhardt R, Ghallab A, Godoy P, Häussinger D, Hammad S, Hoehme S, Holzhütter HG, Klingmüller U, Kuepfer L, Timmer J, Zerial M, Hengstler JG. The virtual liver: state of the art and future perspectives. Arch Toxicol. 2014 Dec;88(12):2071-5. doi: 10.1007/s00204-014-1384-6. PubMed PMID: 25331938.
7: Liu A, Fang H, Wei W, Dirsch O, Dahmen U. Ischemic preconditioning protects against liver ischemia/reperfusion injury via heme oxygenase-1-mediated autophagy. Crit Care Med. 2014 Dec;42(12):e762-71. doi: 10.1097/CCM.0000000000000659. PubMed PMID: 25402296.
8: Liu A, Fang H, Wei W, Kan C, Xie C, Dahmen U, Dirsch O. G-CSF pretreatment aggravates LPS-associated microcirculatory dysfunction and acute liver injury after partial hepatectomy in rats. Histochem Cell Biol. 2014 Dec;142(6):667-76. doi: 10.1007/s00418-014-1242-x. Epub 2014 Jul 25. PubMed PMID: 25059648.
9: Xie C, Wei W, Zhang T, Dirsch O, Dahmen U. Monitoring of systemic and hepatic hemodynamic parameters in mice. J Vis Exp. 2014 Oct 4;(92):e51955. doi: 10.3791/51955. PubMed PMID: 25350047; PubMed Central PMCID: PMC4692415.
10: Deng M, Dahmen U, Sun J, Huang H, Sehestedt C, Homeyer A, Schenk A, Dirsch O. Limited correlation between conventional pathologist and automatic computer-assisted quantification of hepatic steatosis due to difference between event-based and surface-based analysis. IEEE J Biomed Health Inform. 2014 Jul;18(4):1473-7. doi: 10.1109/JBHI.2013.2282999. Epub 2013 Nov 5. PubMed PMID: 24235313.
11: Huang H, Deng M, Jin H, Liu A, Dahmen U, Dirsch O. Reduced hepatic arterial perfusion impairs the recovery from focal hepatic venous outflow obstruction in liver-resected rats. Transplantation. 2014 May 27;97(10):1009-18. doi: 10.1097/TP.0000000000000089. PubMed PMID: 24770620.
12: Hammad S, Hoehme S, Friebel A, von Recklinghausen I, Othman A, Begher-Tibbe B, Reif R, Godoy P, Johann T, Vartak A, Golka K, Bucur PO, Vibert E, Marchan R, Christ B, Dooley S, Meyer C, Ilkavets I, Dahmen U, Dirsch O, Böttger J, Gebhardt R, Drasdo D, Hengstler JG. Protocols for staining of bile canalicular and sinusoidal networks of human, mouse and pig livers, three-dimensional reconstruction and quantification of tissue microarchitecture by image processing and analysis. Arch Toxicol. 2014 May;88(5):1161-83. doi: 10.1007/s00204-014-1243-5. Epub 2014 Apr 19. PubMed PMID: 24748404; PubMed Central PMCID: PMC3996365.
13: Hohmann N, Weiwei W, Dahmen U, Dirsch O, Deutsch A, Voss-Böhme A. How does a single cell know when the liver has reached its correct size? PLoS One. 2014 Apr 1;9(4):e93207. doi: 10.1371/journal.pone.0093207. eCollection 2014. PubMed PMID: 24690888; PubMed Central PMCID: PMC3972176.
14: Meng Z, Ma Z, Zhang E, Kosinska AD, Liu J, Zhang X, Zhou T, Wu J, Dahmen U, Dirsch O, Yang D, Roggendorf M, Lu M. Novel Woodchuck Hepatitis Virus (WHV) transgene mouse models show sex-dependent WHV replicative activity and development of spontaneous immune responses to WHV proteins. J Virol. 2014 Feb;88(3):1573-81. doi: 10.1128/JVI.02086-13. Epub 2013 Nov 20. PubMed PMID: 24257601; PubMed Central PMCID: PMC3911616.
15: Schleicher J, Guthke R, Dahmen U, Dirsch O, Holzhuetter HG, Schuster S. A theoretical study of lipid accumulation in the liver-implications for nonalcoholic fatty liver disease. Biochim Biophys Acta. 2014 Jan;1841(1):62-9. doi: 10.1016/j.bbalip.2013.08.016. Epub 2013 Aug 30. PubMed PMID: 23999488.
16: Zhang H, Wang W, Fang H, Yang Y, Li X, He J, Jiang X, Wang W, Liu S, Hu J, Liu A, Dahmen U, Dirsch O. GSK-3β inhibition attenuates CLP-induced liver injury by reducing inflammation and hepatic cell apoptosis. Mediators Inflamm. 2014;2014:629507. doi: 10.1155/2014/629507. Epub 2014 Nov 30. PubMed PMID: 25525303; PubMed Central PMCID: PMC4265684.
Publikationen 2013
1: Terbonssen T, Settmacher U, Dirsch O, Dahmen U. [Knowledge, trust, and the decision to donate organs : A comparison of medical students and students of other disciplines in Germany]. Chirurg. 2018 Feb;89(2):131-137. doi: 10.1007/s00104-017-0508-y. German. PubMed PMID: 28894905.
2: Deng M, Dahmen U, Sun J, Huang H, Sehestedt C, Homeyer A, Schenk A, Dirsch O. Limited correlation between conventional pathologist and automatic computer-assisted quantification of hepatic steatosis due to difference between event-based and surface-based analysis. IEEE J Biomed Health Inform. 2014 Jul;18(4):1473-7. doi: 10.1109/JBHI.2013.2282999. Epub 2013 Nov 5. PubMed PMID: 24235313.
3: Meng Z, Ma Z, Zhang E, Kosinska AD, Liu J, Zhang X, Zhou T, Wu J, Dahmen U, Dirsch O, Yang D, Roggendorf M, Lu M. Novel Woodchuck Hepatitis Virus (WHV) transgene mouse models show sex-dependent WHV replicative activity and
development of spontaneous immune responses to WHV proteins. J Virol. 2014 Feb;88(3):1573-81. doi: 10.1128/JVI.02086-13. Epub 2013 Nov 20. PubMed PMID: 24257601; PubMed Central PMCID: PMC3911616.
4: Schleicher J, Guthke R, Dahmen U, Dirsch O, Holzhuetter HG, Schuster S. A theoretical study of lipid accumulation in the liver-implications for nonalcoholic fatty liver disease. Biochim Biophys Acta. 2014 Jan;1841(1):62-9. doi: 10.1016/j.bbalip.2013.08.016. Epub 2013 Aug 30. PubMed PMID: 23999488.
5: Dahmen U, Sänger C, Wurst C, Arlt J, Wei W, Dondorf F, Richter B, Settmacher U, Dirsch O. [Video-based self-control in surgical teaching. A new tool in a new concept]. Chirurg. 2013 Oct;84(10):851-8. doi: 10.1007/s00104-013-2528-6. Review. German. PubMed PMID: 24036590.
6: Fang H, Liu A, Dirsch O, Dahmen U. Liver transplantation and inflammation: is lipopolysaccharide binding protein the link? Cytokine. 2013 Oct;64(1):71-8. doi: 10.1016/j.cyto.2013.07.025. Epub 2013 Aug 16. PubMed PMID: 23958732.
7: Godoy P, Hewitt NJ, Albrecht U, Andersen ME, Ansari N, Bhattacharya S, Bode JG, Bolleyn J, Borner C, Böttger J, Braeuning A, Budinsky RA, Burkhardt B, Cameron NR, Camussi G, Cho CS, Choi YJ, Craig Rowlands J, Dahmen U, Damm G, Dirsch O, Donato MT, Dong J, Dooley S, Drasdo D, Eakins R, Ferreira KS, Fonsato V, Fraczek J, Gebhardt R, Gibson A, Glanemann M, Goldring CE, Gómez-Lechón MJ, Groothuis GM, Gustavsson L, Guyot C, Hallifax D, Hammad S, Hayward A, Häussinger
D, Hellerbrand C, Hewitt P, Hoehme S, Holzhütter HG, Houston JB, Hrach J, Ito K, Jaeschke H, Keitel V, Kelm JM, Kevin Park B, Kordes C, Kullak-Ublick GA, LeCluyse EL, Lu P, Luebke-Wheeler J, Lutz A, Maltman DJ, Matz-Soja M, McMullen P, Merfort
I, Messner S, Meyer C, Mwinyi J, Naisbitt DJ, Nussler AK, Olinga P, Pampaloni F, Pi J, Pluta L, Przyborski SA, Ramachandran A, Rogiers V, Rowe C, Schelcher C, Schmich K, Schwarz M, Singh B, Stelzer EH, Stieger B, Stöber R, Sugiyama Y, Tetta
C, Thasler WE, Vanhaecke T, Vinken M, Weiss TS, Widera A, Woods CG, Xu JJ, Yarborough KM, Hengstler JG. Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver
cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME. Arch Toxicol. 2013 Aug;87(8):1315-530. doi: 10.1007/s00204-013-1078-5. Epub 2013 Aug 23. Review. PubMed PMID: 23974980; PubMed Central PMCID: PMC3753504.
8: Liu A, Fang H, Dahmen U, Dirsch O. Chronic lithium treatment protects against liver ischemia/reperfusion injury in rats. Liver Transpl. 2013 Jul;19(7):762-72. doi: 10.1002/lt.23666. PubMed PMID: 23696274.
9: Fang H, Liu A, Dahmen U, Dirsch O. Dual role of chloroquine in liver ischemia reperfusion injury: reduction of liver damage in early phase, but aggravation in late phase. Cell Death Dis. 2013 Jun 27;4:e694. doi: 10.1038/cddis.2013.225. PubMed PMID: 23807223; PubMed Central PMCID: PMC3702304.
10: Homeyer A, Schenk A, Arlt J, Dahmen U, Dirsch O, Hahn HK. Practical quantification of necrosis in histological whole-slide images. Comput Med Imaging Graph. 2013 Jun;37(4):313-22. doi: 10.1016/j.compmedimag.2013.05.002. Epub 2013 Jun 21. PubMed PMID: 23796718.
11: Liu A, Fang H, Yang Y, Sun J, Fan H, Liu S, Dirsch O, Dahmen U. The fibrin-derived peptide bβ15-42 attenuates liver damage in a rat model of liver ischemia/reperfusion injury. Shock. 2013 Apr;39(4):397-403. doi: 10.1097/SHK.0b013e31828c2b75. PubMed PMID: 23503399.
12: Schwier M, Böhler T, Hahn HK, Dahmen U, Dirsch O. Registration of histological whole slide images guided by vessel structures. J Pathol Inform. 2013 Mar 30;4(Suppl):S10. doi: 10.4103/2153-3539.109868. Print 2013. PubMed PMID: 23766932; PubMed Central PMCID: PMC3678747.
13: Huang H, Deng M, Jin H, Dirsch O, Dahmen U. Preventing intra-abdominal adhesions with a sodium hyaluronate carboxymethylcellulose membrane enabled visualization of hepatic microcirculation. Int J Surg. 2013;11(9):935-43. doi: 10.1016/j.ijsu.2013.06.842. Epub 2013 Jul 3. PubMed PMID: 23831750.
14: Fang H, Liu A, Sun J, Kitz A, Dirsch O, Dahmen U. Granulocyte colony stimulating factor induces lipopolysaccharide (LPS) sensitization via upregulation of LPS binding protein in rat. PLoS One. 2013;8(2):e56654. doi: 10.1371/journal.pone.0056654. Epub 2013 Feb 20. PubMed PMID: 23437199; PubMed Central PMCID: PMC3577878.
Publikationen 2012
1: Terbonssen T, Settmacher U, Wurst C, Dirsch O, Dahmen U. Effectiveness of Organ Donation Information Campaigns in Germany: A Facebook Based Online Survey. Interact J Med Res. 2015 Jul 28;4(3):e16. doi: 10.2196/ijmr.4287. PubMed PMID:
26220442; PubMed Central PMCID: PMC4705356.
2: Schwen LO, Wei W, Gremse F, Ehling J, Wang L, Dahmen U, Preusser T. Algorithmically generated rodent hepatic vascular trees in arbitrary detail. J Theor Biol. 2015 Jan 21;365:289-300. doi: 10.1016/j.jtbi.2014.10.026. Epub 2014 Nov 5. PubMed PMID: 25451523.
3: Fang H, Liu A, Dirsch O, Sun J, Jin H, Lu M, Yang D, Dahmen U. Serum LBP levels reflect the impaired synthetic capacity of the remnant liver after partial hepatectomy in rats. J Immunol Methods. 2012 Aug 31;382(1-2):68-75. doi: 10.1016/j.jim.2012.05.006. Epub 2012 May 8. PubMed PMID: 22580761.
4: Jin H, Huang H, Dong W, Sun J, Liu A, Deng M, Dirsch O, Dahmen U. Preliminary experience of a PDCA-cycle and quality management based training curriculum for rat liver transplantation. J Surg Res. 2012 Aug;176(2):409-22. doi: 10.1016/j.jss.2011.10.010. Epub 2011 Nov 10. PubMed PMID: 22261586.
5: Jin H, Dahmen U, Liu A, Huang H, Gu Y, Dirsch O. Prolonged cold ischemia does not trigger lethal rejection or accelerate the acute rejection in two allogeneic rat liver transplantation models. J Surg Res. 2012 Jun 15;175(2):322-32. doi: 10.1016/j.jss.2011.03.078. Epub 2011 Apr 28. PubMed PMID: 21612794.
6: Liu A, Fang H, Dirsch O, Jin H, Dahmen U. Early release of macrophage migration inhibitory factor after liver ischemia and reperfusion injury in rats. Cytokine. 2012 Jan;57(1):150-7. doi: 10.1016/j.cyto.2011.11.009. Epub 2011 Dec 3. PubMed PMID: 22136975.
7: Jin H, Huang H, Zhang J, Dirsch O, Dahmen U. How similar are inbred rats? The influence of anatomical variations, shipment and sampling time on experimental surgery. Eur Surg Res. 2012;49(2):53-65. doi: 10.1159/000333395. Epub 2012 Jul 17. PubMed PMID: 22813726.
8: Liu A, Fang H, Dirsch O, Jin H, Dahmen U. Oxidation of HMGB1 causes attenuation of its pro-inflammatory activity and occurs during liver ischemia and reperfusion. PLoS One. 2012;7(4):e35379. doi: 10.1371/journal.pone.0035379. Epub 2012 Apr 13. PubMed PMID: 22514737; PubMed Central PMCID: PMC3325960.
9: Homeyer A, Schenk A, Dahmen U, Dirsch O, Huang H, Hahn HK. A comparison of sampling strategies for histological image analysis. J Pathol Inform. 2011;2:S11. doi: 10.4103/2153-3539.92034. Epub 2012 Jan 19. PubMed PMID: 22811955; PubMed
Central PMCID: PMC3312717.
Publikationen 2011
1: Terbonssen T, Settmacher U, Dirsch O, Dahmen U. [Knowledge, trust, and the decision to donate organs : A comparison of medical students and students of other disciplines in Germany]. Chirurg. 2018 Feb;89(2):131-137. doi: 10.1007/s00104-017-0508-y. German. PubMed PMID: 28894905.
2: Jin H, Huang H, Dong W, Sun J, Liu A, Deng M, Dirsch O, Dahmen U. Preliminary experience of a PDCA-cycle and quality management based training curriculum for rat liver transplantation. J Surg Res. 2012 Aug;176(2):409-22. doi: 10.1016/j.jss.2011.10.010. Epub 2011 Nov 10. PubMed PMID: 22261586.
3: Jin H, Dahmen U, Liu A, Huang H, Gu Y, Dirsch O. Prolonged cold ischemia does not trigger lethal rejection or accelerate the acute rejection in two allogeneic rat liver transplantation models. J Surg Res. 2012 Jun 15;175(2):322-32. doi: 10.1016/j.jss.2011.03.078. Epub 2011 Apr 28. PubMed PMID: 21612794.
4: Liu A, Fang H, Dirsch O, Jin H, Dahmen U. Early release of macrophage migration inhibitory factor after liver ischemia and reperfusion injury in rats. Cytokine. 2012 Jan;57(1):150-7. doi: 10.1016/j.cyto.2011.11.009. Epub 2011 Dec 3. PubMed PMID: 22136975.
5: Huang H, Deng M, Jin H, Liu A, Dirsch O, Dahmen U. Hepatic arterial perfusion is essential for the spontaneous recovery from focal hepatic venous outflow obstruction in rats. Am J Transplant. 2011 Nov;11(11):2342-52. doi: 10.1111/j.1600-6143.2011.03682.x. Epub 2011 Aug 10. PubMed PMID: 21831159.
6: Liu A, Dirsch O, Fang H, Dong W, Jin H, Huang H, Sun J, Dahmen U. HMGB1 translocation and expression is caused by warm ischemia reperfusion injury, but not by partial hepatectomy in rats. Exp Mol Pathol. 2011 Oct;91(2):502-8. doi: 10.1016/j.yexmp.2011.05.005. Epub 2011 May 27. PubMed PMID: 21640719.
7: Deng M, Huang H, Jin H, Dirsch O, Dahmen U. The anti-proliferative side effects of AEE788, a tyrosine kinase inhibitor blocking both EGF- and VEGF-receptor, are liver-size-dependent after partial hepatectomy in rats. Invest New Drugs. 2011 Aug;29(4):593-606. doi: 10.1007/s10637-010-9394-6. Epub 2010 Feb 12. PubMed PMID: 20148349.
8: Liu A, Dirsch O, Fang H, Sun J, Jin H, Dong W, Dahmen U. HMGB1 in ischemic and non-ischemic liver after selective warm ischemia/reperfusion in rat. Histochem Cell Biol. 2011 May;135(5):443-52. doi: 10.1007/s00418-011-0802-6. Epub 2011 Mar
24. PubMed PMID: 21431875.
9: Huang H, Deng M, Jin H, Liu A, Dirsch O, Dahmen U. A novel end-to-side anastomosis technique for hepatic rearterialization in rat orthotopic liver transplantation to accommodate size mismatches between vessels. Eur Surg Res. 2011;47(2):53-62. doi: 10.1159/000324905. Epub 2011 Jun 1. Review. PubMed PMID: 21646785.
10: Homeyer A, Schenk A, Dahmen U, Dirsch O, Huang H, Hahn HK. A comparison of sampling strategies for histological image analysis. J Pathol Inform. 2011;2:S11. doi: 10.4103/2153-3539.92034. Epub 2012 Jan 19. PubMed PMID: 22811955; PubMed
Central PMCID: PMC3312717.
Publikationen 2010
1: Deng M, Huang H, Jin H, Dirsch O, Dahmen U. The anti-proliferative side effects of AEE788, a tyrosine kinase inhibitor blocking both EGF- and VEGF-receptor, are liver-size-dependent after partial hepatectomy in rats. Invest New Drugs. 2011 Aug;29(4):593-606. doi: 10.1007/s10637-010-9394-6. Epub 2010 Feb 12. PubMed PMID: 20148349.
2: Ghanem LY, Dahmen U, Dirsch O, Nosseir MM, Mahmoud SS, Mansour WA. Does granulocyte-colony stimulating factor administration induce damage or repair response in schistosomiasis? World J Hepatol. 2010 Dec 27;2(12):434-41. doi: 10.4254/wjh.v2.i12.434. PubMed PMID: 21191519; PubMed Central PMCID: PMC3010513.
3: Ricken T, Dahmen U, Dirsch O. A biphasic model for sinusoidal liver perfusion remodeling after outflow obstruction. Biomech Model Mechanobiol. 2010 Aug;9(4):435-50. doi: 10.1007/s10237-009-0186-x. Epub 2010 Jan 12. PubMed PMID:
20066463.
4: Huang H, Deng M, Jin H, Dirsch O, Dahmen U. Intraoperative vital and haemodynamic monitoring using an integrated multiple-channel monitor in rats. Lab Anim. 2010 Jul;44(3):254-63. doi: 10.1258/la.2009.009055. Epub 2010 Feb 11.
PubMed PMID: 20150209.
5: Ivanovska T, Schenk A, Homeyer A, Deng M, Dahmen U, Dirsch O, Hahn HK, Linsen L. A fast and robust hepatocyte quantification algorithm including vein processing. BMC Bioinformatics. 2010 Mar 10;11:124. doi: 10.1186/1471-2105-11-124. PubMed PMID: 20219107; PubMed Central PMCID: PMC2848235.
6: Deng M, Huang H, Dirsch O, Dahmen U. Effect and risk of AEE788, a dual tyrosine kinase inhibitor, on regeneration in a rat liver resection model. Eur Surg Res. 2010;44(2):82-95. doi: 10.1159/000275818. Epub 2010 Jan 19. PubMed PMID: 20090347.
7: Liu A, Jin H, Dirsch O, Deng M, Huang H, Bröcker-Preuss M, Dahmen U. Release of danger signals during ischemic storage of the liver: a potential marker of organ damage? Mediators Inflamm. 2010;2010:436145. doi: 10.1155/2010/436145. Epub
2010 Dec 21. PubMed PMID: 21197406; PubMed Central PMCID: PMC3010695.