Publications

Izadi M, Wolf D, Seemann E, Ori A, Schwintzer L, Steiniger F, Kessels MM, Qualmann B. (2023)Membrane shapers from two distinct superfamilies cooperate in the development of neuronal morphology.   J Cell Biol. 2023 Aug 7;222(8):e202211032. doi: 10.1083/jcb.202211032. Epub 2023 Jun 15. PMID: 37318382

Lolo FN, Walani N, Seemann E, Zalvidea D, Pavón DM, Cojoc G, Zamai M, Viaris de Lesegno C, Martínez de Benito F, Sánchez-Álvarez M, Uriarte JJ, Echarri A, Jiménez-Carretero D, Escolano JC, Sánchez SA, Caiolfa VR, Navajas D, Trepat X, Guck J, Lamaze C, Roca-Cusachs P, Kessels MM, Qualmann B, Arroyo M, Del Pozo MA. (2023) Caveolin-1 dolines form a distinct and rapid caveolae-independent mechanoadaptation. Nat Cell Biol  2023 Jan;25(1):120-133. doi: 10.1038/s41556-022-01034-3. Epub 2022 Dec 21. PMID: 36543981

Hofbrucker-MacKenzie SA, Seemann E, Westermann M, Qualmann B, Kessels MM.  (2023) Long-term depression in neurons involves temporal and ultra-structural dynamics of phosphatidylinositol-4,5-bisphosphate relying on PIP5K, PTEN and PLC. Commun Biol. 2023 Apr 3;6(1):366. doi: 10.1038/s42003-023-04726-0. PMID: 37012315

González A, Covarrubias-Pinto A, Bhaskara RM, Glogger M, Kuncha SK, Xavier A, Seemann E, Misra M, Hoffmann ME, Bräuning B, Balakrishnan A, Qualmann B, Dötsch V, Schulman BA, Kessels MM, Hübner CA, Heilemann M, Hummer G, Dikić I.  (2023) Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum. Nature. 2023 Jun;618(7964):394-401. doi: 10.1038/s41586-023-06089-2. Epub 2023 May 24. PMID: 37225996

Foronda H, Fu Y, Covarrubias-Pinto A, Bocker HT, González A, Seemann E, Franzka P, Bock A, Bhaskara RM, Liebmann L, Hoffmann ME, Katona I, Koch N, Weis J, Kurth I, Gleeson JG, Reggiori F, Hummer G, Kessels MM, Qualmann B, Mari M, Dikić I, Hübner CA. (2023) Heteromeric clusters of ubiquitinated ER-shaping proteins drive ER-phagy. Nature. 2023 Jun;618(7964):402-410. doi: 10.1038/s41586-023-06090-9. Epub 2023 May 24. PMID: 37225994

Tröger J, Seemann E, Heintzmann R, Kessels MM, Qualmann B. Spinal cord synaptic plasticity by GlyRβ release from receptor fields and syndapin I-dependent uptake. J Neurosci. 2022 Jul 21;42(35):6706–23. doi: 10.1523/JNEUROSCI.2060-21.2022. Epub ahead of print. PMID: 35879097; PMCID: PMC9436020.

Lolo FN, Walani N, Seemann E, Zalvidea D, Pavón DM, Cojoc G, Zamai M, Viaris de Lesegno C, Martínez de Benito F, Sánchez-Álvarez M, Uriarte JJ, Echarri A, Jiménez-Carretero D, Escolano JC, Sánchez SA, Caiolfa VR, Navajas D, Trepat X, Guck J, Lamaze C, Roca-Cusachs P, Kessels MM, Qualmann B, Arroyo M, Del Pozo MA. Caveolin-1 dolines form a distinct and rapid caveolae-independent mechanoadaptation system. Nat Cell Biol. 2022 Dec 21. doi: 10.1038/s41556-022-01034-3. Epub ahead of print. PMID: 36543981.

Shi Y, Zhao K, Yang G, Yu J, Li Y, Kessels MM, Yu L, Qualmann B, Berggren PO, Yang SN. Inositol hexakisphosphate primes syndapin I/PACSIN 1 activation in endocytosis. Cell Mol Life Sci. 2022 May 9;79(6):286. doi: 10.1007/s00018-022-04305-2. PMID: 35534740; PMCID: PMC9085685.

Izadi M, Seemann E, Schlobinski D, Schwintzer L, Qualmann B, KesselsMM (2021) Functional interdependence of the actin nucleator Cobl and Cobl-like in dendritic arbor development, eLife, 2021 Jul 15;10:e67718. doi: 10.7554/eLife.67718

Qualmann B, Kessels MM  (2021) The Role of Protein Arginine Methylation as Post-Translational Modification on Actin Cytoskeletal Components in Neuronal Structure and Function.  Cells. 2021 May 1;10(5):1079. doi: 10.3390/cells10051079.

 Kessels MM, Qualmann B. Interplay between membrane curvature and the actin cytoskeleton. Curr Opin Cell Biol. 2021  68:10-19. doi: 10.1016/j.ceb.2020.08.008.

Ji Y, Koch D, González Delgado J, Günther M, Witte OW, Kessels MM, Frahm C, Qualmann B. (2021) Poststroke dendritic arbor regrowth requires the actin nucleator Cobl. PLoS Biol. 2021 Dec 13;19(12):e3001399. doi: 10.1371/journal.pbio.3001399. eCollection 2021 Dec.

Pekmezovic M, Hovhannisyan H, Gresnigt MS, Iracane E, Oliveira-Pacheco J, Siscar-Lewin S, Seemann E, Qualmann B, Kalkreuter T, Müller S, Kamradt T, Mogavero S, Brunke S, Butler G, Gabaldón T, Hube B. (2021) Candida pathogens induce protective mitochondria-associated type I interferon signalling and a damage-driven response in vaginal epithelial cells. Nat Microbiol. 2021 May;6(5):643-657. doi: 10.1038/s41564-021-00875-2. Epub 2021 Mar 22.

Beer AJ, González Delgado J, Steiniger F, Qualmann B, Kessels MM (2020) The actin nucleator Cobl organises the terminal web of enterocytes. Sci Rep. 2020 10(1):11156. doi: 10.1038/s41598-020-66111-9. PMID: 32636403

Seemann E, Kessels MM, Qualmann B (2020)Freeze-Fracture Replica Immunolabeling of Cryopreserved Membrane Compartments, Cultured Cells and Tissues. Methods Mol Biol. 2169:11-25. doi: 10.1007/978-1-0716-0732-9_2. PMID: 32548815

Tröger J, Hoischen C, Perner B, Monajembashi S, Barbotin A, Löschberger A, Eggeling C, Kessels MM, Qualmann B, Hemmerich P (2020) Comparison of Multiscale Imaging Methods for Brain Research. Cells. 9(6):E1377. doi: 10.3390/cells9061377. PMID: 32492970

Langlhofer G, Schaefer N, Maric HM, Keramidas A, Zhang Y, Baumann P, Blum R, Breitinger U, Strømgaard K, Schlosser A, Kessels MM, Koch D, Qualmann B, Breitinger HG, Lynch JW, Villmann C (2020) A Novel Glycine Receptor Variant with Startle Disease Affects Syndapin I and Glycinergic Inhibition.  J Neurosci. 2020 40(25):4954-4969. doi: 10.1523/J Neurosci. 2490-19.2020. Epub 2020 Apr 30. PMID: 32354853

Koch N, Koch D, Krueger S, Tröger J, Sabanov V, Ahmed T, McMillan LE, Wolf D, Montag D, Kessels MM, Balschun D, Qualmann B (2020) Syndapin I Loss-of-Function in Mice Leads to Schizophrenia-Like Symptoms. . Cereb Cortex. 30(8):4306-4324. doi: 10.1093/cercor/ bhaa013. PMID: 32147734

Kessels MM, Qualmann B (2020) The role of membrane-shaping BAR domain proteins in caveolar invagination: from mechanistic insights to pathophysiological consequences. Biochem Soc Trans. 48(1):137-146. doi: 10.1042/BST20190377. PMID: 32104881 Review.

 Beer AJ, Hertz D, Seemann E, Beretta M, Westermann M, Bauer R, Bauer M, Kessels MM, Qualmann B. (2020) Reduced Mrp2 surface availability as PI3Kγ-mediated hepatocytic dysfunction reflecting a hallmark of cholestasis in sepsis. Sci. Reports, in press.

Kessels MM, Qualmann B. Interplay between membrane curvature and the actin cytoskeleton. Curr Opin Cell Biol. 2020 Sep 11;68:10-19. doi: 10.1016/j.ceb.2020.08.008. Online ahead of print. PMID: 32927373

Wolf D, Hofbrucker-MacKenzie SA, Izadi M, Seemann E, Steiniger F, Schwintzer L, Koch D, Kessels MM, Qualmann B. (2019) Ankyrin repeat-containing N-Ank proteins shape cellular membranes. Nat Cell Biol. 2019 Oct;21(10):1191-1205. doi: 10.1038/s41556-019-0381-7. Epub 2019 Sep 23.PMID: 31548610

Bocker HT, Heinrich T2 Liebmann L, Hennings JC, Seemann E, Gerth M, Jakovcevski I, Preobraschenski J, Kessels MM Westermann M, Isbrandt D, Jahn R, Qualmann B, Hübner CA. (2019) The Na+/H+ Exchanger Nhe1 Modulates Network Excitability via GABA Release. Cereb Cortex 29(10):4263-4276. doi: 10.1093/cercor/bhy308. PMID: 30541023.

 Rhode H, Muckova P, Büchler R, Wendler S, Tautkus B, Vogel M, Moore T, Grosskreutz J, Klemm A, Nabity M. (2019) A next generation setup for pre-fractionation of non-denatured proteins reveals diverse albumin proteoforms each carrying several post-translational modifications. Sci Rep. 2019 :9(1):11733. doi: 10.1038/s41598-019-48278-y.

Izadi M, Hou W, Qualmann B, Kessels MM (2018) Direct effects of Ca2+/calmodulin on actin filament formation. Biochem Biophys Res Commun. 506(2):355-360.

Haag N, Schüler S, Nietzsche S, Hübner CA, Strenzke N, Qualmann B, Kessels MM. (2018) The Actin Nucleator Cobl Is Critical for Centriolar Positioning, Postnatal Planar Cell Polarity Refinement, and Function of the Cochlea. Cell Rep. 24(9):2418-2431.

Hou W, Nemitz S, Schopper S, Nielsen ML, Kessels MM, Qualmann B. (2018) Arginine Methylation by PRMT2 Controls the Functions of the Actin Nucleator Cobl. Dev Cell. 45(2):262-275.

Izadi M, Schlobinski D, Lahr M, Schwintzer L, Qualmann B, Kessels MM.(2018) Cobl-like promotes actin filament formation and dendritic branching using only a single WH2 domain. J Cell Biol.. 217(1):211-230.

Hertz D, Leiske MN, Wloka T, Traeger A, Hartlieb M, Kessels MM, Schubert S, Qualmann B, Schubert US. (2018) Comparison of Random and Gradient Amino Functionalized Poly(2-Oxazoline)s: Can the Transfection Efficiency Be Tuned by the Macromolecular Structure? Polym Chem. 2018, 58:1210-1224.

Seemann E, Sun M, Krueger S, Tröger J, Hou W, Haag N, Schüler S, Westermann M, Huebner CA, Romeike B, Kessels MM, Qualmann B. (2017) Deciphering caveolar functions by syndapin III KO-mediated impairment of caveolar invagination. Elife.. pii: e29854. doi: 10.7554/eLife.29854. PMID: 29202928

Sporny M, Guez-Haddad J, Kreusch A, Shakartzi S, Neznansky A, Cross A, Isupov MN, Qualmann B, Kessels MM, Opatowsky Y. (2017) Structural History of Human SRGAP2 Proteins. Mol Biol Evol. 34(6):1463-1478.

Poesen K, De Schaepdryver M, Stubendorff B, Muckova P, Wendler S, Prell T, Ringer T, Rhode H,  Stevens O, Claeys K, Couwelier G, D'Hondt A, Lamaire N, Tilkin PD, Van Reijen S, Hammer N, Heiling B, Rumpel M, Schenk A, Gunkel A, Witte O, Paquet C, Vandenberghe R, Großkreutz J,  Van Damme P, (2017)Neurofilament markers for ALS correlate with extent of upper and lower motor neuron disease. NEUROLOGY 88, 2017, June 13, 1-8, doi: 10.1212/WNL.0000000000004029

Frahm C, Srivastava A, Schmidt, S, Mueller J, Groth M, Guenther M, Ji Y, Priebe S, Platzer M. Witte OW (2017) Transcriptional Profiling Reveals Protective Mechanisms in Brains of Long-Lived Mice. Neurobiol Aging. 52:23-31. doi: 10.1016/j.neurobiolaging.2016.12.016.

Lu-Walther HW, Hou W, Kielhorn M, Arai Y, Nagai T, Kessels MM, Qualmann B, Heintzmann R. (2016) Nonlinear Structured Illumination Using a Fluorescent Protein Activating at the Readout Wavelength. PLoS One. 2016 Oct 26;11(10):e0165148. doi: 10.1371/journal.pone.0165148.

Weissbach J, Schikora F, Weber A, Kessels M, Posern G. (2016) Myocardin-Related Transcription Factor A Activation by Competition with WH2 Domain Proteins for Actin Binding. Mol Cell Biol. 36:1526-39.  

Wales P, Schuberth CE, Aufschnaiter R, Fels J, García-Aguilar I, Janning A, Dlugos CP, Schäfer-Herte M, Klingner C, Wälte M, Kuhlmann J, Menis E, Hockaday Kang L, Maier KC, Hou W, Higgs HN, Pavenstädt H, Qualmann B, Kessels MM, Martin DE, Mulder B, Wedlich-Söldner R (2016) Calcium-mediated actin reset (CaAR) mediates acute cell adaptations. eLIFE in press.

Reindl J, Pesek J, Krüger T, Wendler S, Nemitz S, Muckova P, Büchler R, Opitz S, Krieg N, Norgauer J, Rhode H. (2016) Proteomic biomarkers for psoriasis and psoriasis arthritis. J Proteomics. 140: 55-61.

Schrödl W, Büchler R, Wendler S, Reinhold P, Muckova P, Reindl J,  Rhode H. (2016)Acute phase proteins as promising biomarkers: Perspectives and limitations for human and veterinary medicine. Proteomics Clinical Applications 10: 10771092.

Büchler R, Wendler S, Muckova P, Großkreutz J, Rhode H. (2016) The intricacy of biomarker complexity - the identification of a genuine proteomic biomarker is more complicated than believed. Proteomics Clinical Applications 10: 1073-1076.

Oeckl P, Jardel C, Salachas F, Lamari, Andersen P, Bowser R, de Carvalho M, Costa J, van Damme P, Gray E, Großkreutz J, Herukka S, Huss A, Jeromin A, Kirby J, Kuzma-Kozakiewicz M, Morelli C, Muckova P, Petri S, Poesen K, Rhode H, Rikardsson A, Robberecht W, Rodríguez Mahillo A, Shaw P, Silani V, Steinacker P, Turner M, Tüzün E, Yetimler B, Ludolph AC and M. Otto M. (2016) Multicenter validation of CSF neurofilaments as diagnostic biomarkers for ALS.Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, DOI:10.3109/21678421.2016.1167913

 Ritorto MS, Rhode H, Vogel A, Borlak J. (2016) Regulation of glycosylphosphatidylinositol-anchored proteins and GPI-phospholipase D in a c-Myc transgenic mouse model of hepatocellular carcinoma and human HCC. Biol Chem. doi: 10.1515/hsz-2016-0133

Muckova P, Wendler S, Rubel D, Büchler R, Alert M, Gross O, Rhode H. (2015) Preclinical Alterations in the Serum of COL(IV)A3-/- Mice as Early Biomarkers of Alport Syndrome. J Proteome Res. 14:5202-14.

Hou W, Izadi M, Nemitz S, Haag N, Kessels MM, Qualmann B. (2015) The Actin Nucleator Cobl Is Controlled by Calcium and Calmodulin. PLoS Biol. 2015 Sep 3;13(9):e1002233. doi: 10.1371/journal.pbio.1002233. eCollection 2015 Sep.

Kessels MM, Qualmann B. (2015) Different functional modes of BAR domain proteins in formation and plasticity of mammalian postsynapses. J Cell Sci. 128(17):3177-3185.

Varga RE, Khundadze M, Damme M, Nietzsche S, Hoffmann B, Stauber T, Koch N, Hennings JC, Franzka P, Huebner AK, Kessels MM, Biskup C, Jentsch TJ, Qualmann B, Braulke T, Kurth I, Beetz C, Hübner CA. (2015) In Vivo Evidence for Lysosome Depletion and Impaired Autophagic Clearance in Hereditary Spastic Paraplegia Type SPG11. PLoS Genet. 2015 Aug 18;11(8):e1005454. doi: 10.1371/journal.pgen.1005454. eCollection 2015 Aug.

Khaminets A, Heinrich T, Mari M, Grumati P, Huebner AK,
Akutsu M, Liebmann L, Stolz A, Nietzsche S, Koch N, Mauthe M, Katona I, Qualmann
B, Weis J, Reggiori F, Kurth I, Hübner CA, Dikic I. (2015) Regulation of endoplasmic reticulum
turnover by selective autophagy. Nature. 522(7556):354-358.

Opitz S, Hannika F, Krüger T, Rhode H.  (2015) The removal of Triton X-100 by dialysis is feasible! Anal Bioanal Chem 407(4): 1107-1118.

Zobel T, Brinkmann K, Koch N, Schneider K, Seemann E, Feige A, Qualmann B, Kessels MM, Bogdan, S. (2015) Cooperative functions of the two F-BAR proteins Cip4 and Nostrin in regulating E-cadherin in epithelial morphogenesis. J Cell Science 128:499-515.

Press AT, Traeger A, Pietsch C, Mosig A, Wagner M, Clemens MG, Jbeily N, Koch N, Gottschaldt M, Bézière N, Ermolayev V, Ntziachristos V, Popp J, Kessels MM, Qualmann B, Schubert US, Bauer M. (2014) Cell type-specific delivery of short interfering RNAs by dye-functionalised theranostic nanoparticles. Nat Commun. 2014 Dec 3;5:5565. doi: 10.1038/ncomms6565.

Koch N, Kobler O, Thomas U, Qualmann B, Kessels MM. (2014) Terminal axonal arborization and synaptic bouton formation critically rely on abp1 and the arp2/3 complex. PLoS One. 2014 May 19;9(5):e97692. doi: 10.1371/journal.pone.0097692. eCollection 2014.

Schneider K, Seemann E, Liebmann L, Ahuja R, Koch D, Westermann M, Huebner CA, Kessels MM, Qualmann B. (2014) ProSAP1 and membrane nanodomain-associated syndapin I promote postsynapse formation and function. J. Cell Biol  205(2):197-215

Del Pino I, Koch D, Schemm R, Qualmann B, Betz H, Paarmann IF (Proteomic analysis of GLYRβ interacting proteins: evidence for syndapin I regulating synaptic glycine receptors. J Biol Chem 289(16):11396-11409.

Baple EL*, Maroofian R*, Chioza BA*, Izadi M*, Cross HE, Al-Turki S, Barwick K, Skrzypiec A, Pawlak R, Wagner K, Coblentz R, Zainy T, Patton MA, Mansour S, Rich P, Qualmann B, Hurles ME, Kessels MM, Crosby AH. (2014) Mutations in KPTN Cause Macrocephaly, Neurodevelopmental Delay, and Seizures. Am J Hum Genet. 94(1):87-94
* Erstautoren

Khundadze M*, Kollmann K*, Koch N*, Biskup C, Nietzsche S, Zimmer G, Hennings JC, Huebner AK, Symmank J, Jahic A, Ilina EI, Karle K, Schöls L, Kessels M, Braulke T, Qualmann B, Kurth I, Beetz C, Hübner CA. (2013) A Hereditary Spastic Paraplegia Mouse Model Supports a Role of ZFYVE26/SPASTIZIN for the Endolysosomal System. PLoS Genet. 2013.Dec;9(12):e1003988, doi 1371/journal.pgen.1003988
* Erstautoren

Krüger T, Lehmann H, Rhode H. (2013) Quality characteristics of single sample preparation steps crucially determine reproducibility and coverage in proteomic studies. 
Anal. Chimica Acta  776:1-10

Krüger T, Lautenschläger J, Grosskreutz J, Rhode H. (2013).
Proteome analysis of body fluids for amyotrophic lateral sclerosis biomarker discovery.
Proteomics Clin. Appl. 7:123-135

Schüler S, Hauptmann J, Perner B, Kessels MM, Englert C, Qualmann B. (2013)
Ciliated sensory hair cell formation and function require the F-BAR protein syndapin I and the WH2 domain-based actin nucleator Cobl.
J. Cell Sci. 126:196-208

Pesek J, Krüger T, Krieg N, Schiel N, Norgauer J, Großkreutz J, Rhode H. (2013) Native proteomic sample preparation of serum, plasma and cerebrospinal fluid - is proteolysis actually important?
J. Chromatogr. B, 923-924: 102-109

Pohl M, Danz K, Gross O, John U, Urban J, Patzer L, Habbig S, Feldkötter M, Witzke O, Walther M, Rhode H. (2013) Diagnosis of Alport syndrome - search for proteomic biomarkers in body fluids. Pediatric Nephrology, 28:2117-2123

Pesek J, Krüger T, Tautkus B, Rhode H. (2013) Colorful quality control of chromatographic sample preparation.,
J. Chromatogr. B,  934:66-70

Beetz C, Koch N, Khundadze M, Zimmer G, Nietzsche S, Hertel N, Huebner AK, Mumtaz R, Schweizer M, Dirren E, Karle KN, Irintchev A, Alvarez V, Redies C, Westermann M, Kurth I, Deufel T, Kessels MM, Qualmann B, Hübner CA. (2013) A spastic paraplegia mouse model reveals REEP1-dependent ER shaping. J Clin Invest. 123:4273-4282

Nolze A, Schneider J, Keil R, Lederer M, Hüttelmaier S, Kessels MM, Qualmann B, Hatzfeld M. (2013) FMRP regulates actin filament organization via the armadillo protein p0071. RNA. 19:1483-1496

Wendler S, Tautkus B, Nemitz S, Pesek J, Krüger T, Opitz S, Bartz M, Richter S, Oehme H, Haenel T, Moore T, Kreusch S, Hanf B,. Schmidt L, Rhode H. (2013) Automated native sample preparation for proteome analysis. Buchbeitrag Chapter 1, 1-50: In: Automation Systems of the 21th Century, Nova Science Publishers, NY, 2013, ISBN: 978-1-62948-262-0

Koch, D., Spiwoks-Becker, I., Sabanov, V., Sinning, A., Dugladze, T., Stellmacher, A., Ahuja, R., Grimm, J., Schüler, S., Müller, A., Angenstein, F., Ahmed, T., Diesler, A., Moser, M., Tom Dieck, S., Spessert, R., Boeckers, T.M., Fässler, R., Hübner, C.A., Balschun, D., Gloveli, T., Kessels, M.M., Qualmann, B. (2011).
Proper synaptic vesicle formation and neuronal network activity critically rely on syndapin I. EMBO J., 30, 4955-4969

Schwintzer, L., Koch, N., Ahuja, R., Grimm, J., Kessels, M.M., Qualmann, B. (2011).
The functions of the actin nucleator Cobl in cellular morphogenesis critically depend on syndapin I. EMBO J.,30, 303147-303159

Qualmann B, Koch D, Kessels MM (2011).
Let’s go bananas: Revisiting the endocytic BAR code. EMBO J., 30, 3501-3515 

Kessels, M.M., Schwintzer, L., Schlobinski, D., Qualmann, B. (2011).
Controlling actin cytoskeletal organization and dynamics during neuronal morphogenesis.
Eur. J. Cell Biol., 90, 926-933 

Koch, D., Spiwoks-Becker, I., Sabanov, V., Sinning, A., Dugladze, T., Stellmacher, A., Ahuja, R., Grimm, J., Schüler, S., Müller, A., Angenstein, F., Ahmed, T., Diesler, A., Moser, M., Tom Dieck, S., Spessert, R., Boeckers, T.M., Fässler, R., Hübner, C.A., Balschun, D., Gloveli, T., Kessels, M.M., Qualmann, B. (2011).
Proper synaptic vesicle formation and neuronal network activity critically rely on syndapin I. EMBO J., 30, 4955-4969

Schwintzer, L., Koch, N., Ahuja, R., Grimm, J., Kessels, M.M., Qualmann, B. (2011).
The functions of the actin nucleator Cobl in cellular morphogenesis critically depend on syndapin I. EMBO J.,30, 303147-303159

Qualmann B, Koch D, Kessels MM (2011).
Let’s go bananas: Revisiting the endocytic BAR code. EMBO J., 30, 3501-3515 

Kessels, M.M., Schwintzer, L., Schlobinski, D., Qualmann, B. (2011).
Controlling actin cytoskeletal organization and dynamics during neuronal morphogenesis.
Eur. J. Cell Biol., 90, 926-933 

Hallbauer, J., Kreusch, S., Klemm, A., Wolf, G., Rhode, H. (2010).
Long-term serum proteomes are quite similar under high- and low-flux hemodialysis treatment.Proteomics Clin. Appl., 4, 953-961

2009

Dharmalingam, E., Haeckel, A., Pinyol, R., Schwintzer, L., Koch, D., Kessels, M.M., Qualmann, B. (2009).
F-BAR proteins of the syndapin family shape the plasma membrane and are crucial for neuromorphogenesis.
J. Neurosci., 29, 13715-13727

Fricke, R., Gohl, C., Dharmalingam, E., Grevelhörster, A., Zahedi, B., Harden, N., Kessels, M.M., Qualmann, B., Bogdan, S. (2009).
Drosophila Cip4/Toca-1 Integrates Membrane Trafficking and Actin Dynamics through WASP and SCAR/WAVE.
Curr. Biol., 19, 1429-1437

Qualmann B., Kessels M.M. (2009).
New players in actin polymerization--WH2-domain-containing actin nucleators.
Trends Cell Biol., 19, 276-285.

Salvarezza, S.B., Deborde, S., Schreiner, R., Campagne, F., Kessels, M.M., Qualmann, B., Caceres, A., Kreitzer, G., Rodriguez-Boulan, E. (2009).
LIM kinase 1 and cofilin regulate actin filament population required for dynamin-dependent apical carrier fission from the trans-Golgi network.
Mol. Biol. Cell, 20, 438-451.

2008

Haeckel, A., Ahuja, R., Gundelfinger, E.D., Qualmann, B., Kessels, M.M. (2008).
The actin-binding protein Abp1 controls dendritic spine morphology and is important for spine head and synapse formation.
J. Neurosci., 28, 10031-10044.

Qualmann, B., Kessels, M.M. (2008).
Actin nucleation: putting the brakes on Arp2/3.
Curr. Biol., 18, R420-423.

Onabajo, O.O., Seeley, M.K., Kale, A., Qualmann, B., Kessels, M., Han, J., Tan, T.H., Song, W. (2008).
Actin-binding protein 1 regulates B cell receptor-mediated antigen processing and presentation in response to B cell receptor activation.
J. Immunol., 180, 6685-6689.

Kreusch, S., Schulze, M., Cumme, G.A., Ditze, G., Moore, T, Rhode, H. (2008).
Searching biomarker candidates in serum using multidimensional native chromatography. I. Enhanced separation method.
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 875, 567-572.

Baum, A., Pohl. M., Kreusch, S., Cumme, G.A., Ditze, G., Misselwitz, J., Kiehntopf, M., Udby, L., Meier-Hellmann, A., Rhode, H. (2008).
Serum Biomarker search in serum using multidimensional native chromatography - II Method evaluation with Alport Syndrome and Severe Inflammation.
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 876, 31-40.

Schurigt, U., Hummel, K.M., Petrow, P.K., Gajda, M., Stöckigt, R., Middel, P., Zwerina, J., Janik, T., Bernhardt, R., Schüler, S., Scharnweber, D., Beckmann, F., Saftig, P., Kollias, G., Schett, G., Wiederanders, B., Bräuer, R. (2008).
Cathepsin K deficiency partially inhibits, but does not prevent, bone destruction in human tumor necrosis factor-transgenic mice.
Arthritis Rheum. 58, 422-434.

Cumme, G.A., K,reusch, S., Nagel, M., Rhode, H. (2008).
Multidimensional chromatography: Validation and efficient fishing for biomarkers and fractions containing them using the VisualCockpit software package.
Proteomics, 8, 37-41.

2007

Ahuja R, Pinyol R, Reichenbach N, Custer L, Klingensmith J, Kessels MM, Qualmann B. (2007)
Cordon-bleu is an actin nucleation factor and controls neuronal morphology. Cell, 131, 337-350.

Pinyol, R., Haeckel, A., Ritter, A., Qualmann, B., Kessels, M.M. (2007).
Regulation of N-WASP and the Arp2/3 complex by Abp1 controls neuronal morphology.
PLoS ONE, 2, e400. doi:10.1371/journal.pone.0000400

Ruettger A, Schueler S, Mollenhauer JA, Wiederanders B. (2007)
Cathepsins B, K and L are regulated by a defined collagen type II peptide via activation of classical protein kinase C and p38 MAP kinase in articular chondrocytes.
J. Biol. Chem. 283, 1043-1051

Kramer, G., Paul, A., Kreusch, A., Schüler, S., Wiederanders, B. and Schilling, K. (2007)
Optimized folding and activation of recombinant procathepsin L and S produced in Escherichia coli.
Protein Expr. Purif. 54, 147-156

Tsareva, S. A., Moriggl, R., Corvinus, F. M., Wiederanders, B., Schütz, A., Kovacic, B. and Friedrich, K. (2007)
Signal transducer and activator of trascription 3 activation promotes invasive growth of colon carcinomas through matrix metalloproteinase induction.
Neoplasia 9, 279-291

Mitre, E., Schulze, M., Cumme, G. A., Rößler, F., Rausch, T. and Rhode, H. (2007)
Turbo-Mixing in microplates.
J. Biomol. Screening 12, 361-369

2006

Kessels, M.M., Qualmann, B. (2006)
Syndapin oligomers interconnect the machineries for endocytic vesicle formation and the actin cytoskeleton.
J. Biol. Chem., 281, 13285-13299.

Kessels, M.M., Dong, J., Leibig, W., Westermann, P., Qualmann, B. (2006) Complexes of syndapin II with dynamin II promote vesicle formation at the trans-Golgi network.
J. Cell Sci., 119, 1504-1516.

Augsten, M.; Pusch, R.; Biskup, C.; Rennert, K.; Wittig, U.; Beyer, K.; Blume, A., Wetzker, R., Friedrich, K. and Rubio, I. (2006)
Live-cell imaging of endogenous Ras-GTP illustrates predominant Ras activation at the plasma membrane.
EMBO Reports 7, 46-51

Horn, A., Kreusch, S., Bublitz, R., Hoppe, H., Cumme, G. A., Schulze, M., Moore, T., Ditze, G. and Rhode, H. (2006)
Multidimensional proteomics of human serum using parallel chromatography of native constituents and microplate technology, Proteomics, 6, 559-570

Bublitz, R., Kreusch, S., Ditze, G., Schulze, M., Cumme,G. A., Fischer, C., Winter, A., Hoppe, H. and Rhode, H. (2006)
Robust protein quantitation in chromatographic fractions using matrix-assisted laser desorption/ionization mass spectrometry of tryptic peptides. Proteomics, 6, 3909-3917

Schüler, S., Wenz, I., Wiederanders, B., Slickers, P. and Ehricht, R. (2006) An alternative method to amplify RNA without loss of signal conservation for expression analysis with a Proteinase DNA microarray in the ArrayTube format.
BMC Genomics 7, 144

Rüttger, A., Mollenhauer, J., Löser, R., Gütschow, M., and Wiederanders, B. (2006)
Microplate assay for quantitative determination of cathepsin activities in viable cells using derivatives of 4-methoxy-β-naphthylamide. BioTechniques 41, 469-473.

Rhode, H., Kreusch, S., Cumme, G. A., Baum, A., Pohl, M., Moore, T. and Meier-Hellmann, A. (2006)
Search for serum biomarkers using an approach based on native multidimesional fractionation. Shock 26, suppl 1, 1

Ruckrich, T., Brandenburg, J., Cansier, A., Muller, M., Stevanovic, S., Schilling, K., Wiederanders, B., Beck, A., Melms, A., Reich, M., Driessen, C. and Kalbacher, H. (2006) Specificity of human cathepsin S determined by processing of peptide substrates and MHC class II-associated invariant chain. Biolo. Chem. 387, 1503-1511.

Kaulmann G., Palm, G. J., Schilling, K., Hilgenfeld, R. and Wiederanders, B. (2006)
The crystal structure of a Cys25 -> Ala mutant of human procathepsin S elucidates enzyme-prosequence interactions.
Protein Sci. 15, 2619-2629.

2005

Braun, A., Pinyol, R., Dahlhaus, R., Koch, D., Fonarev, P., Grant, B.D., Kessels, M.M., Qualmann, B. (2005).
EHD proteins associate with syndapin I and II and such interactions play a crucial role in endosomal recycling.
Mol. Biol. Cell, 16, 3642-3658.

tom Dieck, S., Altrock, W.D., Kessels, M.M., Qualmann, B., Regus, H., Brauner, D, Fejtová, A., Bracko, O., Gundelfinger, E.D., Brandstätter, J.H. (2005).
Molecular dissection of the photoreceptor ribbon synapse: physical interaction of Bassoon and RIBEYE is essential for the assembly of a functional ribbon complex.
J. Cell Biol., 168, 825-836.

Sachse, A., Wagner, A., Keller, M., Wagner, O., Wetzel, W. D., Layher, F., Venbrocks, R. A., Hortschansky, P., Pietrasnzyk, M., Wiederanders, B., Hempel, H. J., Bossert, J., Horn, J., Schmuck, K. and Mollenhauer, J. (2005)
Osteointegration of hydroxyapatite-titanium implants coated with nonglycosylated recombinant human bone morphogenetic protein-2 (BMP-2) in aged sheep. Bone 37, 699-710

Schurigt, U., Stopfel, N., Hueckel, M., Pfirschke, C., Wiederanders, B. and Brauer, R. (2005)
Local expression of matrix metalloproteinases, cathepsins, and their inhibitors during the development of murine antigen-induced arthritis.
Arthr. Res. Ther. 7, R174-R188

Loser, R., Schilling, K., Dimmig, E. and Gutschow M. (2005)
Interaction of papain-like cysteine proteases with dipeptide-derived nitriles.
J. Med. Chem. 48 , 7688-7707

Fitzgerald, J. S., Tsareva, S. A., Poehlmann, T. G., Berod, L., Meissner, A., Corvinus, F. M., Wiederanders, B., Pfitzner, E., Markert, U. R. and Friedrich K. (2005) Leukemia inhibitory factor triggers activation of signal transducer and activator of transcription 3, proliferation, invasiveness, and altered protease expression in choriocarcinoma cells. International Journal of Biochem. Cell Biol. 37, 2284-2296.

Kreusch, S., Hoppe, H., Bublitz, R., Moore, T., Hallbauer, J. Schulze, M., Cumme, G.A., Misselwitz J., Klemm, A., and Rhode, H. (2005) Non-denaturating multidimensional separation of serum: Improved method, automatization, and applications.
Mol. Cell. Proteomics 4 S1, 211-S211

2004

Kessels, M.M., Qualmann, B. (2004).
The syndapin protein family - linking membrane trafficking with the cytoskeleton.
J. Cell Sci., 117, 3077-3086.

Qualmann, B., Boeckers T.B., Jeromin, M., Gundelfinger, E. D., Kessels, M.M. (2004).
Linkage of the actin cytoskeleton to the postsynaptic density via interactions of Abp1 with ProSAP/Shanks.
J. Neurosci., 24, 2481-2495.

Merrifield, C.J., Qualmann, B., Kessels, M.M., Almers, W. (2004).
Neural Wiskott Aldrich Syndrome Protein (N-WASP) and the Arp2/3 complex are recruited to sites of clathrin-mediated endocytosis in cultured fibroblasts.
Eur. J. Cell Biol., 83, 13-18.

Rhode, H., Schulze, M., Renard, S., Zimmermann, P., Moore, T, Cumme, G. A. and Horn, A. (2004).
An improved method for checking HTS/uHTS liquid-handling systems. J. Biomol. Screening 9, 726-733.

• Nat Rev Mol Cell Biol. 2003: Temporal and spatial coordination of exocytosis and endocytosis.
• J. Cell Biol. 2000: Molecular links between endocytosis and the actin cytoskeleton..