Integrated Biobank Jena

PD Dr. Dr. Michael Kiehntopf

Principal Investigator,
Institute of Clinical Chemistry and Laboratory Diagnostics, Jena University Hospital

Team: Bärbel von der Gönne
Kay Stötzer
Emanuel Ochs

Duration: 01.08.2010 - 31.07.2015

The Integrated Biobank Jena is a central resource for all CSCC clinical studies, and it increasingly includes experimental studies as well.

It is a centralized biobank resource that combines samples from multiple internal and external study sites, such as the CSCC, the Center for Innovation Competence Septomics, and the Sepsis Competence Network SepNet. Additional CSCC funding was invested in improving technology and increasing liquid nitrogen storage capacity. Today, the Integrated Biobank Jena features a scalable, fully-automated robotic storage and retrieval system that works at -80°C and allows the automatic handling, including cherry-picking and storage, of more than 500,000 tubes, all directly connected to a liquid handling workstation. The expanded storage capacity with the new liquid nitrogen storage containers adds additional capacity of > 360,000 tubes for high-quality, long-term storage at very low temperatures. Detailed SOPs and standards for sampling, intermediate storage, transport, splitting, pre-analytical processes, and long-term storage of samples have been implemented and validated to ensure the consistent high quality of sample material. Quality control procedures are certiἀed and approved in accordance with the DIN EN ISO 9001 certiἀed quality management system. All ethical, legal and social implications, quality management, information and communication technologies, and education issues comprehensively inform the biobank concept, and are available for researchers and clinicians to support them in conducting Clinical Trials and research.The Integrated Biobank Jena provides a central biobanking resource for a number of networks, large-scale multi-center sepsis trials, and local clinical trials. The sample size stored in the centralized biobank resource from the ongoing trials in the sepsis cluster is expected to grow over the next two to three years to more than 68,000 primary samples, resulting in approximately 478,000 aliquots of septic patients and appropriate controls. The Integrated Biobank Jena is a central resource for all CSCC clinical studies, and it increasingly includes experimental studies as well.The Integrated Biobank Jena provides a central biobanking resource for a number of networks, large-scale multi-center sepsis trials, and local Clinical Trials.