Functional Proteomics
Functional and clinical proteomics
Princical investigator: Jun.-Prof. Dr. Florian Meier-Rosar
Aberrations in the proteome and cellular signaling pathways are hallmarks of many diseases, including cancer. Our research focuses on developing new technologies to increase throughput, sensitivity, and coverage of proteomic analyses. In particular, we are investigating the application of ion mobility spectrometry for the quantification of proteins and their post-translational modifications in patient-derived cells, biofluids, and tissue samples.
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Selected publications
- Meier, F., et al. diaPASEF: parallel accumulation–serial fragmentation combined with data-independent acquisition. Nature Methods 17, 1229–1236 (2020). https://doi.org/10.1038/s41592-020-00998-0