Andre Schmidt

Dr. rer. nat.

Position

AG-Leiter

Arbeitsgruppe

Plazentatoxikologie

Kontakt

E-Mail:

Forschungsschwerpunkte

Plazenta-Explantate und Zelllinien als in vitro-Modelle in der Toxikologie

Ersatzmethoden zu Tierversuchen

Artunterschiede und Charakteristika der humanen Plazenta

Ersatz von fetalem Kälberserum

Brustkrebs in der Schwangerschaft

Proteomanalysen von Follikelflüssigkeiten

Ausgewählte Publikationen

Hermanns K, Göhner C, Kopp A, Schmidt A, Merz WM, Markert UR, Junglen S, Drosten C, 2018. Zika virus infection in human placental tissue explants is enhanced in the presence of dengue virus antibodies in-vitro, Emerging Microbes & Infections, 7:1, 1-8, DOI: 10.1038/s41426-018-0199-6
Lehmann R, Schmidt A, Pastuschek J, Müller MM, Fritzsche A, Dieterle S, Greb RR, Markert UR, Slevogt H, 2018.
Comparison of sample preparation techniques and data analysis for the LC-MS/MS-based identification of proteins in human follicular fluid. Am J Reprod Immunol, 80(2):e12994. DOI:10.1111/aji.12994
Heger J, Froehlich K, Pastuschek J, Schmidt A, Baer C, Mrowka R, Backsch C, Schleußner E, Markert UR, Schmidt A, 2018. Human serum alters cell culture behavior and improves spheroid formation in comparison to fetal bovine serum. Exp Cell Res, 365(1):57-65. DOI:10.1016/j.yexcr.2018.02.017
Loibl S, Schmidt A, Gentilini O, Kaufman B, Kuhl C, Denkert C, Parokonnaya A, Stensheim H, Thomssen C, Calsteren K, Poortmans P, Berveiller P, Markert U, Amant F, 2017. Breast Cancer (Diagnosed) During Pregnancy: Adapting Recent Advances in Breast Cancer Care for Pregnant Patients. DOI:10.1007/978-3-319-48848-6_59
Froehlich K, Haeger JD, Heger J, Pastuschek J, Photini SM, Yan Y, Lupp A, Pfarrer C, Mrowka R, Schleußner E, Markert UR, Schmidt A, 2016. Generation of Multicellular Breast Cancer Tumor Spheroids: Comparison of Different Protocols. J Mammary Gland Biol Neoplasia 21, 89-98. DOI:10.1007/s10911-016-9359-2
Loibl S, Schmidt A, Gentilini O, Kaufman B, Kuhl C, Denkert C, Parokonnaya A, Stensheim H, Thomssen C, Calsteren K, Poortmans P, Berveiller P, Markert U, Amant F, 2015. Breast Cancer Diagnosed During Pregnancy. JAMA oncology. DOI:10.1001/jamaoncol.2015.2413
Schmidt A, Morales-Prieto DM, Pastuschek J, Fröhlich K, Markert UR. Only humans have human placentas: molecular differences between mice and humans, 2015. Reprod. Immunol. 108 (2015) 65–71. DOI:10.1016/j.jri.2015.03.001
Morales-Prieto DM, Ospina-Prieto S, Schmidt A, Chaiwangyen W, Markert UR, 2014. Elsevier Trophoblast Research Award Lecture: Origin, evolution and future of placenta miRNAs. Placenta 35 Suppl:S39-45. DOI:10.1016/j.placenta.2013.11.017
Schmidt A, Rzanny M, Schmidt A, Hagen M, Schütze E, Kothe E, 2012. GC content-independent amino acid patterns in bacteria and archaea. J Basic Microbiol 52, 195-205. DOI:10.1002/jobm.201100067
Schmidt A, Hagen M, Schütze E, Schmidt A, Kothe E, 2010. In silico prediction of potential metallothioneins and metallohistins in actinobacteria. J Basic Microbiol 50, 562-569. DOI:10.1002/jobm.201000055
Schmidt A, Haferburg G, Schmidt A, Lischke U, Merten D, Gherghel F, Büchel G, Kothe E, 2009. Heavy metal resistance to the extreme – Streptomyces strains from a former uranium mining area. Chemie der Erde – Geochemistry 69S2, 35-44. DOI:10.1016/j.chemer.2007.11.002
Schmidt A, Gube M, Schmidt A, Kothe E, 2009. In silico analysis of nickel containing superoxide dismutase evolution and regulation. J Basic Microbiol 49, 109-118. DOI:10.1002/jobm.200800293
Dimkpa CO, Svatos A, Dabrowska P, Schmidt A, Boland W, Kothe E, 2008. Involvement of siderophores in the reduction of metal-induced inhibition of auxin synthesis in Streptomyces spp. Chemosphere 74, 19-25. DOI:10.1016/j.chemosphere.2008.09.079
Schmidt A, Schmidt A, Haferburg G, Kothe E, 2007. Superoxide dismutases of heavy metal resistant streptomycetes. J Basic Microbiol 47, 56-62. DOI:10.1002/jobm.200610213
Schmidt A, Haferburg G, Sineriz M, Merten D, Büchel G, Kothe E, 2005. Heavy metal resistance mechanisms in actinobacteria for survival in AMD contaminated soils. Chemie der Erde – Geochemistry 65S1, 131-144. DOI:10.1016/j.chemer.2005.06.006