2015

Abo-Zeid MAM, Liehr T, Gamal-Eldeen AM, Zawrah M, Ali M, Othman MAK. Potential of rod, sphere and semi-cube shaped gold nanoparticles to induce cytotoxicity and genotoxicity in human blood lymphocytes in vitro. Eur J Nanomed 2015, 7: 63-75.
Abo-Zeid MAM, Liehr T, Glei M, Gamal-Eldeen AM, Zawrah M, Ali M. Detection of cyto- and genotoxicity of rod-shaped gold nanoparticles in human blood lymphocytes using comet-FISH. Cytologia 2015, 80:173-181.
Aguiar de Oliveira E, Bertollo LAC, Yano CF, Liehr T, de Bello Cioffi M. Comparative cytogenetics in the genus Hoplias (Characiformes, Erythrinidae) highlights contrasting karyotype evolution among congeneric species Mol Cytogenet 2015, 8:56.
Al-Achkar W, Moassass F, Al-Ablog A, Liehr T, Fan X, Wafa A. A Syrian couple with chromosomal aberration and MTHFR polymorphism leads to recurrent pregnancy loss and partial trisomy of 5p12-15.3 in the offspring: Case report and review to the literature. Zhonghua Nan Ke Xue = Nat J Androl 2015; 21:219-224.
Alhourani E, Rincic M, Melo JB, Carreira IM, Glaser A, Pohle B, Schlie C, Liehr T. Isochromosome 17q in chronic lymphocytic leukemia. Leuk Res Treatment 2015, 2015:489592
Armanet N, Tosca L, Brisset S, Liehr T, Tachdjian G. Small supernumerary marker chromosomes in human infertility. Cytogenet Genome Res 2015, 146:100-108.
Baranov VS, Ivaschenko TE, Liehr T, Yarmolinskaya MI. Systems genetics view of endometriosis – a common complex disorder. Eur J Obstet Gynecol Reprod Biol 2015 185:59-65.
Brečević L, Rinčić M, Krsnik Ž, Sedmak G, Hamid AB, Kosyakova N, Galić I, Liehr T, Borovečki F. Association of new deletion/duplication region at chromosome 1p21 with intellectual disability, severe speech deficit and autism spectrum disorder-like behavior: an all-in approach to solving the DPYD enigma. Translat Neuroscience 2015, 6:59-86.
Capela de Matos RR, De Figueiredo AF, Liehr T, Alhourani E, De Souza MT, Abdelhay, E Ribeiro RC, Silva MLM. A novel three-way variant t(8;13;21)(q22;q33;q22) in a child with acute myeloid leukemia FAB AML-M2: contribution of molecular approaches to reveal t(8;21) variants. Acta Hematol 2015;134:243-245.
Chen YC, Auer-Grumbach M, Matsukawa S, Zitzelsberger M, Themistocleous AC, Strom TM, Samara C, Moore AW, Cho LT, Young GT, Weiss C, Schabhüttl M, Stucka R, Schmid AB, Parman Y, Graul-Neumann L, Heinritz W, Passarge E, Watson RM, Hertz JM, Moog U, Baumgartner M, Valente EM, Pereira D, Restrepo CM, Katona I, Dusl M, Stendel C, Wieland T, Stafford F, Reimann F, von Au K, Finke C, Willems PJ, Nahorski MS, Shaikh SS, Carvalho OP, Nicholas AK, Karbani G, McAleer MA, Cilio MR, McHugh JC, Murphy SM, Irvine AD, Jensen UB, Windhager R, Weis J, Bergmann C, Rautenstrauss B, Baets J, De Jonghe P, Reilly MM, Kropatsch R, Kurth I, Chrast R, Michiue T, Bennett DL, Woods CG, Senderek J. Transcriptional regulator PRDM12 is essential for human pain perception. Nat Genet 2015, 47:803-808.
Chen YC, Auer-Grumbach M, Matsukawa S, Zitzelsberger M, Themistocleous AC, Strom TM, Samara C, Moore AW, Cho LT, Young GT, Weiss C, Schabhüttl M, Stucka R, Schmid AB, Parman Y, Graul-Neumann L, Heinritz W, Passarge E, Watson RM, Hertz JM, Moog U, Baumgartner M, Valente EM, Pereira D, Restrepo CM, Katona I, Dusl M, Stendel C, Wieland T, Stafford F, Reimann F, von Au K, Finke C, Willems PJ, Nahorski MS, Shaikh SS, Carvalho OP, Nicholas AK, Karbani G, McAleer MA, Cilio MR, McHugh JC, Murphy SM, Irvine AD, Jensen UB, Windhager R, Weis J, Bergmann C, Rautenstrauss B, Baets J, De Jonghe P, Reilly MM, Kropatsch R, Kurth I, Chrast R, Michiue T, Bennett DL, Woods CG, Senderek J. Corrigendum: Transcriptional regulator PRDM12 is essential for human pain perception. Nat Genet 2015, 47:962.
Darouich AA, Liehr T, Weise A, Schlembach D, Schleußner E, Kiehntopf M, Schreyer I. Alpha-fetoprotein and its value for predicting pregnancy outcomes – a re-evaluation. J Prenat Med 2015;9:18-23.
de Figueiredo AF, Capela de Matos RR, Othman MA, Liehr T, da Costa ES, Land MG, Ribeiro RC, Abdelhay E, Silva ML. Molecular cytogenetic studies characterizing a novel complex karyotype with an uncommon 5q22 deletion in childhood acute myeloid leukemia. Mol Cytogenet 2015, 8:62.
Elert-Dobkowska E, Hennings JC, Hübner CA, Beetz C. Multiplex ligation-dependent probe amplification for identification of correctly targeted murine embryonic stem cell clones. Anal Biochem 2015, 474C:35-37.
Fan X , Supiwong W, Weise A, Mrasek K, Kosyakova N, Tanomtong A, Pinthong K, Trifonov VA, de Bello Cioffi M, Grothmann P, Liehr T, de Oliveira EHC. Comprehensive characterization of evolutionary conserved breakpoints in four New World Monkey karyotypes compared to Chlorocebus aethiops and Homo sapiens. Helyion 1:e00042
Gerstmann K, Zimmer G. Fine-tuning of cortical progenitor proliferation by thalamic afferents. Neural Regen Res 2015, 10:887-888.
Gerstmann K, Pensold D, Symmank J, Khundadze M, Hübner CA, Bolz J, Zimmer G. Thalamic afferents influence cortical progenitors via ephrin A5-EphA4 interactions. Development 2015;142:140-150.
Gomaa IE, Abdel Gaber SA, Bhatt S, Liehr T, Glei M, El-Tayeb TA, Abdel-Kader MH. In vitro cytotoxicity and genotoxicity studies of gold nanoparticles-mediated photo-thermal therapy versus 5-fluorouracil. J Nanopart Res 2015, 17:102.
Gooma IE, Bhatt S, Liehr T, Glei M, El-Tayeb TA. Comparative study of Ag and Co / Ag nanoparticles mediated by photothermal therapy of cancer. Egypt J Zool 2015, 63: 99-117.
Hamid AB, Fan X, Kosyakova N, Radhakrishnan G, Liehr T, Karamysheva T. New BAC probe set to narrow down chromosomal breakpoints in small and large derivative chromosomes, especially suited for mosaic conditions. Methods Mol Biol 2015, 1227:279-287.
Harutyunyan T, Hovhannisyan G, Babayan N, Othman M, Liehr T, Aroutiounian R. Influence of aflatoxin B1 on copy number variants in human leukocytes in vitro. Mol Cytogenet 2015, 8:25.
Hochstenbach R, Nowakowska B, Volleth M, Ummels A, Kutkowska-Kamierczak A, Obersztyn E, Ziemkiewicz K, Gerloff C, Schanze D, Zenker M, Muschke P, Schanze I, Poot M, Liehr T. Multiple small supernumerary marker chromosomes resulting from maternal meiosis I or II errors. Mol Syndromol 2015, 6:210-221.
Hu Z, Qi H, Zhang R, Zhang K, Shi Z, Chang Y, Chen L, Esmaeili M, Baniahmad A, Hong W. Docosahexaenoic acid inhibits the growth of hormone-dependent prostate cancer cells by promoting the degradation of the androgen receptor. Mol Med Rep 2015, 12:3769-3774.
Hübner CA, Schroeder BC, Ehmke H. Regulation of vascular tone and arterial blood pressure: role of chloride transport in vascular smooth muscle. Pflugers Arch. 2015, 467:605-614.
Karamysheva T, Kosyakova N, Guediche N, Liehr. T Small supernumerary marker chromosomes and the nuclear architecture of sperm – a study in a fertile and an infertile brother. Syst Biol Reprod Med 2015, 61:32-36.
Kehrer M, Liehr T, Benkert T, Singer S, Grasshoff U, Schaeferhoff K, Bonin M, Weichselbaum A, Tzschach A. Interstitial duplication of chromosome region 1q25.1q25.3: Report of a patient with mild cognitive deficits, tall stature and facial dysmorphisms. Am J Med Genet A 2015, 167:653-656.
Khaminets A, Heinrich T, Mari M, Grumati P, Huebner AK, Akutsu M, Liebmann L, Stolz A, Nietzsche S, Koch N, Mauthe M, Katona I, Qualmann B, Weis J, Reggiori F, Kurth I, Hübner CA, Dikic I. Regulation of endoplasmic reticulum turnover by selective autophagy. Nature 2015, 522:354-358.
Kirkpatrick G, Ren H, Liehr T, Chow V, Ma S. Meiotic and sperm aneuploidy studies in three carriers of Robertsonian translocations and small supernumerary marker chromosomes. Fertil Steril 2015, 103:1162–1169.e7.
Kontodiou M, Daskalakis G, Vetro A, Paspaliaris V, Papaioannou G, Dagklis T, Tsakiridis I, Ziegler M, Liehr T, Thomaidis L, Papoulidis I, Manolakos E. Complex rearrangement involving three chromosomes, four breakpoints and a 2.7-Mb deletion in the 18q segment observed in a girl with mild learning difficulties. Cytogenet Genome Res 2015;147:118-123.
Kurth I. [Sensory and autonomic neuropathies and pain-related channelopathies]. Schmerz 2015, 29:445-457.
Jafari-Ghahfarokhi H, Moradi-Chaleshtori M, Liehr T, Hashemzadeh-Chaleshtori M, Teimori H, Ghasemi-Dehkordi P. Small supernumerary marker chromosomes and their correlation with specific syndromes. Adv Biomed Res 2015, 4:140.
Jahic A, Khundadze M, Jaenisch N, Schüle R, Klimpe S, Klebe S, Frahm C, Kassubek J, Stevanin G, Schöls L, Brice A, Hübner CA, Beetz C. The spectrum of KIAA0196 variants, and characterization of a murine knockout: implications for the mutational mechanism in hereditary spastic paraplegia type SPG8. Orphanet J Rare Dis. 2015 Nov 16;10(1):147.
Lange M, Kasper B, Bohring A, Rutsch F, Kluger G, Hoffjan S, Spranger S, Behnecke A, Ferbert A, Hahn A, Oehl-Jaschkowitz B, Graul-Neumann L, Diepold K, Schreyer I, Bernhard MK, Mueller F, Siebers-Renelt U, Beleza-Meireles A, Uyanik G, Janssens S, Boltshauser E, Winkler J, Schuierer G, Hehr U. 47 patients with FLNA associated periventricular nodular heterotopia. Orphanet J Rare Dis 2015;10:134.
Ledig S, Preisler-Adams S, Morlot S, Liehr T, Wieacker P. Premature ovarian failure caused by a heterozygous missense mutation in POF1B and a reciprocal translocation 46,X,t(X;3)(q21.1;q21.3). Sex Dev 2015, 9:86-90.
Leipold E, Hanson-Kahn A, Frick M, Gong P, Bernstein JA, Voigt M, Katona I, Oliver Goral R, Altmüller J, Nürnberg P, Weis J, Hübner CA, Heinemann SH, Kurth I. Cold-aggravated pain in humans caused by a hyperactive NaV1.9 channel mutant. Nat Commun 2015, 6:10049.
Liehr T, Heng H, Yurov Y, Meloni-Ehrig A, Iourov I. Reviewer acknowledgement 2015. Mol Cytogenet 2015, 8:23.
Liehr T, Othman MA, Rittscher K, Alhourani E. The current state of molecular cytogenetics in cancer diagnosis. Expert Rev Mol Diagn 2015, 15:517-526.
Maass PG, Aydin A, Luft FC, Schächterle C, Weise A, Stricker S, Lindschau C, Vaegler M, Qadri F, Toka HR, Schulz H, Krawitz PM, Parkhomchuk D, Hecht J, Hollfinger I, Wefeld-Neuenfeld Y, Bartels-Klein E, Mühl A, Kann M, Schuster H, Chitayat D, Bialer MG, Wienker TF, Ott J, Rittscher K, Liehr T, Jordan J, Plessis G, Tank J, Mai K, Naraghi R, Hodge R, Hopp M, Hattenbach LO, Busjahn A, Rauch A, Vandeput F, Gong M, Rüschendorf F, Hübner N, Haller H, Mundlos S, Bilginturan N, Movsesian MA, Klussmann E, Toka O, Bähring S. PDE3A mutations cause autosomal-dominant hypertension with brachydactyly. Nat Genet 2015, 46:647-653.
Manvelyan M, Simonyan I, Hovhannisyan G, Aroutiounian R, Hamid AB, Liehr T. A new case of a complex small supernumerary marker chromosome, a der(9)t(7;9)(p22;q22) due to a maternal balanced rearrangement. J Ped Genet 2015, 4:199-200.
Maslova A, Zlotina A, Kosyakova N, Sidorova M, Krasikova A. Three-dimensional architecture of tandem repeats in chicken interphase nucleus. Chromosome Res. 2015, 23:625-639.
Moysés-Oliveira , Guilherme RS, Dantas AG, Ueta R, Perez AB, Haidar M, Canonaco R, Meloni VA, Kosyakova N, Liehr T, Carvalheira GM, Melaragno MI. Genetic mechanisms leading to primary amenorrhea in balanced X-autosome translocations. Fertil Steril 2015, 103:1289-1296.
Moysés-Oliveira M, Guilherme RS, Meloni VA, Di Battista A, de Mello CB, Bragagnolo S, Moretti-Ferreira D, Kosyakova N, Liehr T, Carvalheira GM, Melaragno MI. X-linked intellectual disability related genes disrupted by balanced X-autosome translocations. Am J Med Genet B Neuropsychiatr Genet 2015, 168:669-677.
Mrasek K, Wilhelm K, Quintana LG, Theuss L, Liehr T, Leskovac A, Filipovic J, Joksic G, Joksic I, Weise A. BAC-probes applied for characterization of fragile sites (FS). Methods Mol Biol 2015, 1227:289-298.
Ney Garcia DR, Liehr T, Emerenciano M, Meyer C, Marschalek R, Pombo-de-Oliveira Mdo S, Ribeiro RC, Poirot Land MG, Macedo Silva ML. Molecular studies reveal MLL-MLLT3 gene fusion displaced in a case of childhood acute lymphoblastic leukemia with complex karyotype. Cancer Genet 2015, 208:143-147.
Othman MAK, Melo JB, Carreira IM, Rincic M, Alhourani E, Wilhelm K, Gruhn B, Glaser A, Liehr T. MLLT10 and IL3 rearrangement together with a complex four-way-translocation and trisomy 4 in a patient with early T-cell precursor acute lymphoblastic leukemia. Oncol Rep 2015, 33: 625-630.
Othman MAK, Vujić D, Zecević , Đurišić M, Slavković B, Meyer B, Liehr T. A cryptic three-way translocation t(10;19;11)(p12.31;q13.31;q23.3) with a derivative Y-chromosome in an infant with acute myeloblastic leukemia (M5b). Gene 2015, 563:115-119.
Othman MAK, Grygalewicz B, Pienkowska-Grela B, Rincic M, Rittscher K, Melo JB, Carreira IM, Meyer B, Marzena W, Liehr T. Novel cryptic rearrangements in adult B cell precursor acute lymphoblastic leukemia involving MLL gene. J Histochem Cytochem 2015, 63:384-390.
Othman MAK, Melo JB, Carreira IM, Rincic M, Glaser A, Grygalewicz B, Gruhn B, Wilhelm K, Rittscher K, Meyer B, Silva MLM, de Jesus Marques Salles T, Liehr T. High rates of submicroscopic aberrations in karyotypically normal acute lymphoblastic leukemia. Mol Cytogenet 2015, 8:45.
Perner S, Cronauer MV, Schrader AJ, Klocker H, Culig Z, Baniahmad A. Adaptive responses of androgen receptor signaling in castration-resistant prostate cancer. Oncotarget 2015, 6:35542-35555.
Petroff D, Kromeyer-Hauschild K, Wiegand S, l'Allemand-Jander D, Binder G, Schwab KO, Stachow R, Kiess W, Hammer E, Sturm S, Holl RW, Blüher S. Introducing excess body weight in childhood and adolescence and comparison with body mass index and waist-to-height ratio. Int J Obes (Lond) 2015, 39:52-60.
Rath M, Najm J, Sirb H, Kentouche K, Dufke A, Pauli S, Hackmann K, Liehr T, Hübner CA, Felbor U, Kompetenznetzwerk Hämorrhagische Diathesen Ost (KHDO). Large deletions play a minor but essential role in congenital coagulation factor VII and X deficiencies. Hämostaseologie 2015, 35:S36-42.
Reichwald K, Petzold A, Koch P, Downie BR, Hartmann N, Pietsch S, Baumgart M, Chalopin D, Felder M, Bens M, Sahm A, Szafranski K, Taudien S, Groth M, Arisi I, Weise A, Bhatt SS, Sharma V, Kraus JM, Schmid F, Priebe S, Liehr T, Görlach M, Than ME, Hiller M, Kestler HA, Volff J-N, Schartl M, Cellerino A, Englert C, Platzer M. Insights into sex chromosome evolution and aging from the genome of a short-lived fish. Cell 2015, 163:1527-1538
Romanenko SA, Perelman PL, Trifonov VA, Serdyukova NA, Li T, Fu B, O'Brien PC, Ng BL, Nie W, Liehr T, Stanyon R, Graphodatsky AS, Yang F. A First generation comparative chromosome map between guinea pig (Cavia porcellus) and humans. PLoS One 2015,10:e0127937
Sahoo T, Wang J-C, Elnaggar MM, Sanchez-Lara P, Ross LP, Mahon LW, Hafezi K, Deming A, Hinman L, Bruno Y, Bartley JA, Liehr T, Anguiano A, Jones M. Concurrent interstitial triplication and segmental uniparental disomy: Providing evidence for microhomology-mediated break-induced replication model for complex genomic rearrangements in humans. Europ J Hum Genet 2015, 23:61-66.
Schaefer N, Kluck CJ, Price KL, Meiselbach H, Vornberger N, Schwarzinger S, Hartmann S, Langlhofer G, Schulz S, Schlegel N, Brockmann K, Lynch B, Becker CM, Lummis SC, Villmann C. Disturbed neuronal ER-Golgi sorting of unassembled glycine receptors suggests altered subcellular processing is a cause of human hyperekplexia. J Neurosci. 2015 Jan 7;35(1):422-37.
Schnetzke U, Spies-Weisshart B, Yomade O, Fischer M, Rachow T, Schrenk K, Glaser A, von Lilienfeld-Toal M, Hochhaus A, Scholl S. Polymorphisms of Toll-like receptors (TLR2 and TLR4) are associated with the risk of infectious complications in acute myeloid leukemia. Genes Immun 2015, 16:83-88.
Scholten M, Vilser C, Weise A, Baniahmad A. Atypical polycystic ovary syndrome - a genetic analysis. Exp Clin Endocrinol Diabetes 2015, 123:55-60.
Sheth F, Rahman M, Liehr T, Desai M, Patel B, Modi C, Trivedi S, Sheth J. Prenatal screening of cytogenetic anomalies – a Western Indian experience. BMC Preg Childbirth 2015, 15:90.
Sheth F, Liehr T, Shah K, Sheth J. Prader-Willi syndrome - type 1 deletion, a consequence of an unbalanced translocation of chromosomes 13 and 15, easily to be mixed up with a Robertsonian translocation. Mol Cytogenetics 2015, 8:52.
Sinning A, Liebmann L, Hübner CA. Disruption of Slc4a10 augments neuronal excitability and modulates synaptic short-term plasticity. Front Cell Neurosci 2015, 9:223.
Tzschach A, Grasshoff U, Beck-Woedl S, Dufke C, Bauer C, Kehrer M, Evers C, Moog U, Oehl-Jaschkowitz B, Di Donato N, Maiwald R, Jung C, Kuechler A, Schulz S, Meinecke P, Spranger S, Kohlhase J, Seidel J, Reif S, Rieger M, Riess A, Sturm M, Bickmann J, Schroeder C, Dufke A, Riess O, Bauer P. Next-generation sequencing in X-linked intellectual disability. Eur J Hum Genet. 2015, 23:1513-1518.
Tkach IR, Sosnina KO, Huleyuk NL, Terpylyak OI, Zastavna DV, Weise A, Kosyakova N, Liehr T. Contribution of chromosomal abnormalities and genes of the major histocompatibility complex to early pregnancy losses. Biopolymers and Cell 2015, 31:38-45.
Varga RE, Khundadze M, Damme M, Nietzsche S, Hoffmann B, Stauber T, Koch N, Hennings JC, Franzka P, Huebner AK, Kessels MM, Biskup C, Jentsch TJ, Qualmann B, Braulke T, Kurth I, Beetz C, Hübner CA. In vivo evidence for lysosome depletion and impaired autophagic clearance in hereditary spastic paraplegia type SPG11. PLoS Genet 2015, 11:e1005454.
Wafa A, Asa'ad M, Ikhtiar A, Liehr T, Al-Achkar W. Deletion 9p23 to 9p11.1 as sole additional abnormality in a Philadelphia positive chronic myeloid leukemia in blast crisis: a rare event. Mol Cytogenet 2015, 8:59.
Wafa A, Almedani A, Liehr T, Al-Achkar W. Masked inv dup(22)(q11.23), tetrasomy 8 and trisomy 19 in a blast crisis-chronic myeloid leukemia after interrupted Imatinib-treatment. Mol Cytogenet 2015, 8:98.
Weise A, Othman MA, Bhatt S, Löhmer S, Liehr T. Application of BAC-probes to visualize copy number variants (CNVs). Methods Mol Biol 2015, 1227:299-307.
Weise A, Kosyakova N, Voigt M, Aust N, Mrasek K, Löhmer S, Rubtsov N, Karamysheva T, Trifonov V, Hardekopf D, Jancuková , Pekova S, Wilhelm K, Liehr T, Fan X. Comprehensive analyses of white handed gibbon chromosomes enables access to 92 evolutionary conserved breakpoints compared to the human genome. Cytogenet Genome Res 2015,145:42-49.
Winkler S, Hempel M, Brückner S, Mallek F, Weise A, Liehr T, Tautenhahn HM, Bartels M, Christ B. Mouse white adipose tissue-derived mesenchymal stem cells gain pericentral and periportal hepatocyte features after differentiation in vitro, which are preserved in vivo after hepatic transplantation. Acta Physiol 2015, 215:89-104
Woods CG, Babiker MO, Horrocks I, Tolmie J, Kurth I. The phenotype of congenital insensitivity to pain due to the NaV1.9 variant p.L811P. Eur J Hum Genet 2015, 23:561-563.
Woods CG, Babiker MO, Horrocks I, Tolmie J, Kurth I. The phenotype of congenital insensitivity to pain due to the NaV1.9 variant p.L811P. Eur J Hum Genet 2015, 23:1434.
Zonouzi M, Scafidi J, Li P, McEllin B, Edwards J, Dupree JL, Harvey L, Sun D, Hübner CA, Cull-Candy SG, Farrant M, Gallo V. GABAergic regulation of cerebellar NG2 cell development is altered in perinatal white matter injury. Nat Neurosci 2015, 18:674-682.