Publikationen

M Dabaghi and I Hilger (2020). „Magnetic Nanoparticles Behavior in Biological Solutions; The Impact of Clustering Tendency on Sedimentation Velocity and Cell Uptake”. Materials 2020, 13(7), 1644; doi: 10.3390/ma13071644

M Dabaghi, R Quaas and I Hilger. "The Treatment of Heterotopic Human Colon Xenograft Tumors in Mice with 5-Fluorouracil Attached to Magnetic Nanoparticles in Combination with Magnetic Hyperthermia Is More Efficient than Either Therapy Alone." Cancers 2020, 12(9), 2562; doi: 10.3390/cancers12092562

F Gaffron, A Tilch, C Grüttner, A Kowalski, M Kramer, U Teichgräber and I Hilger, (2020).  “Challenges in Tracking of Fluorochrome-Labelled Nanoparticles in Mice via Whole Body NIRF Imaging”; Nanomaterials 2020, 10(3), 596; doi: 10.3390/nano10030596

S Ley, B Faenger, I Hilger and M Helbig, "MNP Enhanced Microwave Imaging by Means of Pseudo-Noise Sensing with Different External Magnetic Field Modulations," 2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), Montreal, QC, Canada, 2020, pp. 1795-1798, doi: 10.1109/EMBC44109.2020.9175940.

S Ley, B Faenger, J Sachs, I Hilger and M Helbig, "Investigation of Influences on the Detectability of Magnetic Nanoparticles by Means of Microwaves for Biomedical Applications," 2020 14th European Conference on Antennas and Propagation (EuCAP), Copenhagen, Denmark, 2020, pp. 1-4, doi: 10.23919/EuCAP48036.2020.9135345.

S Piehler, H Dähring, J Grandke, J Göring, P Couleaud, A Aires, A L Cortajarena, J Courty, A Latorre, Al Somoza, U Teichgräber and I Hilger, (2020). “Iron Oxide Nanoparticles as carriers for DOX and Magnetic Hyperthermia after intratumoral application into Breast Cancer in Mice: Impact and future Perspectives”; Nanomaterials 2020, 10(6), 1016; doi: 10.3390/nano10061016

S Piehler, L Wucherpfennig, F L Tansi, A Berndt, R Quaas, U Teichgraeber, I Hilger (2020). “Hyperthermia affects collagen fiber architecture and induces apoptosis in pancreatic and fibroblast tumor hetero-spheroids in vitro”; Nanomedicine: Nanotechnology, Biology and Medicine 26 (2020); doi: 10.1016/j.nano.2020.102183

F L Tansi, R Rüger, A M Kollmeier, M Rabenhold, F Steiniger, R E Kontermann, U Teichgräber, A Fahr and I Hilger (2020). „Targeting the Tumor Microenvironment with Fluorescence-Activatable Bispecific Endoglin/Fibroblast Activation Protein Targeting Liposomes”; Pharmaceutics 2020, 12(4), 370; doi: 10.3390/pharmaceutics12040370

F L Tansi, R Rüger, C Böhm, F Steiniger, M Raasch, A S Mosig, R E Kontermann, U Teichgräber, A Fahr and I Hilger (2020). “Rapid Target Binding and Cargo Release of Activatable Liposomes Bearing HER2 and FAP Single-Chain Antibody Fragments Reveal Potentials for Image-Guided Delivery to Tumors”; Pharmaceutics 2020, 12(10):E972; doi: 10.3390/pharmaceutics12100972

C Anders, A Huebner, B Faenger; „Die neuromuskuläre Effizienz von Rumpfmuskeln - unerwartete Einflüsse von Geschlecht und Alter“ In book: Prävention von arbeitsbedingten Gesundheitsgefahren und Erkrankungen : 25. Erfurter Tage, Chapter: Angewandte Präventionsforschung zu Erkrankungen des Bewegungssystems, Publisher: Bussert u. Stadeler, 2019, Editors: Isabel Dienstbühl, Martina Stadeler, Hans-Christoph Scholle, pp.183-192; ISBN: 978-3-942115-51-3

M Ebbinghaus, S Müller, G Segond von Banchet, A Eitner, I Wank, A Hess, I Hilger, T Kamradt, H-G Schaible (2019). “Contribution of Inflammation and Bone Destruction to Pain in Arthritis: A Study in Murine Glucose-6-Phosphate Isomerase–Induced Arthritis”; Arthritis and Rheumatology.; First published: 22 July 2019; doi: 10.1002/art.41051.

B Faenger, N P Schumann, C Anders, D Arnold, R Grassme, O Guntinas-Lichius, and H-C Scholle. “Comparison between Intramuscular Multichannel Electrodes and Supramysial Multichannel Electrodes via EMG Measurements for Potential Use as Larynx Stimulation Electrodes: In Vivo Animal Analysis” Sensors, vol. 19, no. 20, pp. 4477, 2019; doi: 10.3390/s19204477

M Sanhaji , J Göring, P Couleaud, A Aires, AL Cortajarena, J Courty, A Prina-Mello, M Stapf, R Ludwig, Y Volkov, A Latorre, Á Somoza, R Miranda, I Hilger. “The phenotype of target pancreatic cancer cells influences cell death by magnetic hyperthermia with nanoparticles carrying gemicitabine and the pseudo-peptide NucAnt.” Nanomedicine. 2019 Aug; 20:101983; doi: 10.1016/j.nano.2018.12.019

F L Tansi, M P Filatova, D O Koroev, O M Volpina, S Lange, C Schumann, U Teichgräber, S Reissmann, I Hilger. (2019). „New generation CPPs show distinct selectivity for cancer and noncancer cells.”; Journal of Cellular Biochemistry;  doi: 10.1002/jcb.27943

C Anders, A Huebner, B Faenger (2018). The Neuromuscular Efficiency of Trunk Muscles is Altered by Age in the Abdominal Muscles but by Gender in the Back Muscles; International Journal of Sports and Exercise Medicine; Int J Sports Exerc Med, 4:089; doi: 10.23937/2469-5718/1510089

F L Tansi, R Rüger, A M Kollmeier, M Rabenhold, F Steiniger, R E Kontermann, U Teichgraeber, A Fahr, I Hilger. (2018). Dataset on the role of endoglin expression on melanin production in murine melanoma and on the influence of melanin on optical imaging; Data Brief; 20:1048-1052; doi:10.1016/ j.dib.2018.08.110

F L Tansi, R Rüger, A M Kollmeier, M Rabenhold, F Steiniger, R E Kontermann, U Teichgraeber, A Fahr, I Hilger (2018). Endoglin based in vivo near-infrared fluorescence imaging of tumor models in mice using activatable liposomes; Biochim Biophys Acta Gen Subj.; 1862(6):1389-1400. doi: 10.1016/j.bbagen.2018.03.012

M Stapf, U Teichgraeber, I Hilger (2017). Methotrexate-coupled nanoparticles and magnetic nanochemothermia for the relapse-free treatment of T24 bladder tumors; International Journal of Nanomedicine 2017:12 2793-2811, doi: 10.2147/IJN.S120969

B Faenger, S Ley, M Helbig, J Sachs, I Hilger (2017). Breast phantom with a conductive skin layer and conductive 3D-printed anatomical structures for microwave imaging, 11th European Conference on Antennas and Propagation (EUCAP), Paris, France, pp. 1065-1068. doi: 10.23919/EuCAP.2017.7928662

F Tansi, R Rüger, C Böhm, R E Kontermann, U Teichgräber, A Fahr, I Hilger (2017). Activatable bispecific liposomes bearing fibroblast activation protein directed single chain fragment/Trastuzumab deliver encapsulated cargo into the nuclei of tumor cells and the tumor microenvironment simultaneously; Acta Biomarterialia (2017) 54:281-293: doi: 10.1016/j.actbio.2017.03.033

F Tansi, R Rüger, A Kollmeier, C Böhm, R E. Kontermann, U Teichgräber, A Fahr, I Hilger (2017). A fast and effective determination of the biodistribution and subcellular localization of fluorescent immunoliposomes in freshly excised animal organs; BMC Biotechnology 17:8, doi:  Artn 8. 10.1186/S12896-017-0327-8

J Jung-König, M, Sanhaji, R Popescu, C Seidl, E Zittel, U Schepers, D Gerthsen, I Hilger, C Feldmann (2017). Microemulsion-made gadolinium carbonate hollow nanospheres showing magnetothermal heating and drug release; Nanosclae; DOI: 10.1039/c7nr01784g

Hallasch, S., Frick, S., Jung, M. & Hilger, I (2017). How gastrin-releasing peptide receptor (GRPR) and αvβ3 integrin expression reflect regrow features of tumors after hyperthermia treatments. Scientific Reports 7. Doi: 10.1038/s41598-017-06100-7.

J Sachs, S Ley, M Helbig, B Faenger, I Hilger (2017). Differential Microwave Imaging in Medicine based on Ultra-Wideband Pseudo-Noise MIMO-Radar; International Microwave Bio-Conference; IEEE Xplore, doi: 10.1109/IMBIOC.2017.7965770

S Ley, M Helbig, J Sachs, B Faenger, I Hilger (2017). Initial Volunteer Trial Based on Ultra-Wideband Pseudo-Noise Radar, International Microwave Bio-Conference; IEEE Xplore

S Ley, M Helbig, J Sachs, B Faenger, I Hilger (2017). Investigations of Signal Reproducibility and Influences of Vital Signs for Microwave Breast Cancer Imaging: An Initial Volunteer Trial; IMBIOC conference Göteborg, doi: 10.1109/IMBIOC.2017.7965799

F Tansi, R Rüger, C Böhm, R E Kontermann, U Teichgräber, A Fahr, I Hilger (2016). Dataset on FAP-induced emergence of spontaneous metastases and on the preparation of activatable FAP-targeting immunoliposomes to detect the metastases; Data Brief; 2016; 9; 143-8.

F Tansi, R Rüger, C Böhm, R E Kontermann, U Teichgräber, A Fahr, I Hilger (2016). Potential of activatable FAP-targeting immunoliposomes in intraoperative imaging of spontaneous metastases; Biomaterials 88:70-82; DOI:10.1016/j.biomaterials.2016.02.028

M Stapf, N Pömpner, U Teichgräber, I Hilger (2016) Heterogeneous response of different tumor cell lines to methotrexate-coupled nanoparticles in presence of hyperthermia; International Journal of Nanomedicine, 11:485-500; DOI:https://dx.doi.org/10.2147/IJN.S94384

V Weiss, C Argyo, AA Torrano, C Strobel, SA Mackowiak, A Schmidt, S Datz, T Gatzenmeier, I Hilger, C Bräuchle, T Bein, (2016) Dendronized Mesoporous Silica Nanoparticles Provide an Internal Endosomal Escape Mechanism for Successful Cytosolic Drug Release, Microporous and Mesoporous Materials 227:242-251; DOI:10.1016/j.micromeso.2016.03.017

K Haedicke, S Gräfe, U Teichgräber, I Hilger (2016) Lowering photosensitizer doses and increasing fluences induce apoptosis in tumor bearing mice; Biomedical Optics Express,7:2641-2649; DOI:10.1364/BOE.7.002641

AA Torrano, R Herrmann, C Strobel, M Rennhak, H Engelke, A Reller, I Hilger, A Wixforth, C Bräuchle (2016). Cell membrane penetration and mitochondrial targeting by platinum-decorated ceria nanoparticles, Nanoscale, 8:13352-13367; DOI:10.1039/c5nr08419a

J Domey, C Bergemann, S Bremer-Streck, I Krumbein, J R Reichenbach, U Teichgräber, I Hilger (2016). Long-term prevalence of NIRF-labeled magnetic nanoparticles for the diagnostic and intraoperative imaging of inflammation; Nanotoxicology; 10; 1; 20-31. 

R Ludwig, FJ Teran, U Teichgräber, I Hilger (2016). Nanoparticle-based hyperthermia distinctly impacts production of ROS, expression of Ki-67, TOP2A, and TPX2, and induction of apoptosis in pancreatic cancer; International Journal of Nanomedicine; 2016; 11; 1–10.

F  Tansi, R Rüger, M Rabenhold, F Steiniger, A Fahr, I Hilger (2015). Fluorescence-quenching of a liposomal-encapsulated near-infrared fluorophore as a tool for in vivo optical imaging. J. Vis. Exp. (95), e52136, doi:10.3791/52136

L Landgraf, I Müller, P Ernst, M Schäfer, C Rosman, I Schick, O Köhler, H Oehring, V V Breus, T Basché, C Sönnichsen, W Tremel and I Hilger (2015). Comparative evaluation of the impact on endothelial cells induced by different nanoparticle structures and functionalization. Beilstein J. Nanotechnology 6:300–312

J Domey, C Bergemann, S Bremer-Streck, I Krumbein, JR Reichenbach, U Teichgräber, I Hilger (2015).  Long term prevalence of NIRF-labeledmagnetic nanoparticles for the diagnostic and intraoperative imaging of inflammation.Journal Nanotoxicology 17:1-12

M Stapf, N Pömpner, M Kettering, I Hilger (2015). Magnetic thermoablation stimuli alter BCL2, HSP70 and FGF-R1 expression profiles in BT474 breast tumors. International Journal of Nanomedicine 10:1931–1939

K Haedicke, D Kozlova, S Gräfe, U Teichgräber, M Epple, I Hilger (2015) . Multifunctional calcium phosphate nanoparticles for combining near-infrared fluorescence optical imaging and photodynamic therapy. Acta Biomaterialia 14:197-207

H Dähring, J Grandke, V Patel, I Hilger (2015). Improved Hyperthermia Treatment of Tumors Under Consideration of Magnetic Nanoparticle Distribution Using Micro-CT Imaging. Molecular Imaging & Biology DOI: 10.1007/s11307-015-0848-2

S Kossatz, J Grandke, P Couleaud, A Latorre, A Aires, K  Crosbie-Staunton, R Ludwig, H Dähring, V Ettelt, A Lazaro-Carrillo, M Calero, M Sader, J Courty, Y Volkov, A Prina-Mello, Á Villanueva, Á Somoza, A L Cortajarena, R Miranda,  I Hilger (2015). Efficient treatment of breast cancer xenografts with multifunctionalized iron oxide nanoparticles combining magnetic hyperthermia and anti-cancer drug delivery. Breast Cancer Research 17:66  doi:10.1186/s13058-015-0576-1

C Strobel, H Oehring, R Herrmann, M Förster, A Reller, I Hilger (2015). Fate of cerium dioxide nanoparticles in endothelial cells: exocytosis. Journal of Nanoparticle Research  17:206; DOI 10.1007/s11051-015-3007-4

J Domey, U Teichgräber, I Hilger (2015). Gold nanoparticles allow detection of early-stage edema in mice via computed tomography imaging. International Journal of nanomedicine  10:1–12

R P Friedrich, C Janko, M Pöttler, PTripal, J Zaloga, I Cicha, S Dürr, J Nowak, S Odenbach, I Slabu, L Trahms, M Stapf, I Hilger, S Lyer, C Alexiou (2015). Flow cytometry for intracellular SPION quantification: specificity and sensitivity in comparison with spectroscopic methods. International Journal of Nanomedicine  10:4185–4201

F Tansi, E Kallweit,  C Kaether, K Kappe, C Schumann, I Hilger, S Reissmann (2015). Internalization of near-infrared fluorescently labeled activatable cell-penetrating peptide and of proteins into human fibrosarcoma cell line HT-1080. Journal of Cellular Biochemistry 116:1222–1231

S Dutz, R Müller, D Eberbeck, I Hilger, M Zeisberger (2015). Magnetic Nanoparticles Adapted for Specific Biomedical Applications. Biomedical Engineering/Biomedizinische Technik  DOI 10.1515/bmt-2015-0044

P Radon, M Liebl, N Pömpner, M Stapf, F Wiekhorst, K Gitter, I Hilger, S Odenbach, L Trahms (2015). Magnetic Particle Spectroscopy to Determine the Magnetic Drug Targeting Efficiency of Different Magnetic Nanoparticles in a Flow Phantom. IEEE TRANSACTION ON MAGNETICS 51(2)

J Zaloga, M Stapf, J Nowak, M Pöttler, R P Friedrich, R Tietze, S Lyer, G Lee, S Odenbach, I Hilger, C Alexiou (2015).Tangential flow ultrafiltration allows purification and concentration of lauric acid/albumin coated particles for improved magnetic treatment. International Journal of Molecular Sciences 16:19291-19307

R Ludwig, M Stapf, S Dutz, R Müller, U Teichgräber, I Hilger (2014). Structural properties of magnetic nanoparticles determine their heating behavior - an estimation of the in vivo heating potential. Nanoscale Research Letters, 9:602.

G Salas, J Camarero, D Cabrera, H Takacs, M Varela, R Ludwig, H Dähring, I Hilger, R Miranda, M del Puerto Morales, F J Teran (2014). Modulation of Magnetic Heating via Dipolar Magnetic Interactions in Monodisperse and Crystalline Iron Oxide Nanoparticles. Journal of Physical Chemistry C, 118, 19985−19994.

F L Tansi, R Rüger, M Rabenhold, F Steiniger, A Fahr, I Hilger (2014). Fluorescence-quenching of a liposomal-encapsulated near-infrared fluorophore as a tool for in vivo optical imaging. Journal of Visualized Experiments, in press.

C Strobel, M Förster, I Hilger (2014). Biocompatibility of cerium dioxide and silicon dioxide nanoparticles on endothelial cells. Beilstein Journal of Nanotechnology,5, 1795–1807.

R Rüger, F  Tansi, M Rabenhold, F Steiniger, R E Kontermann, A Fahr, I Hilger (2014). In vivo near-infrared fluorescence imaging of FAP-expressing tumors with activatable FAP-targeted, single-chain Fv-Immunoliposomes. Journal of Controlled Release, 186:1-10.

S Kossatz, R Ludwig, H Dähring, V Ettelt, G Rimkus, M Marciello, G Salas, V Patel, F  Teran, I Hilger. (2014) High Therapeutic Efficiency of Magnetic Hyperthermia in Xenograft Models Achieved with Moderate Temperature Increases in the Tumor Area. Pharmaceutical Research, DOI: 10.1007/s11095-014-1417-0

D Fischer, I Hilger (2014). Nanopartikel: Innovative Anwendungsgebiete in der Diagnostik und vor allem in der Therapie. Deutsche Apotheker Zeitung, 154. Jahrgang, Nr.13.

L Landgraf, P Ernst, I Schick, O Köhler, H Oehring, W Tremel, I Hilger (2014).  Anti-oxidative effects and harmlessness of asymmetric Au@Fe3O4 Janus particles on human blood cells. Biomaterials,  35:25, 6986–6997.

C Strobel, A A Torrano, R Herrmann, M Malissek, C Bräuchle, A Reller, L Treuel, W A Kaiser, I Hilger (2014). Effects of the physicochemical properties of titanium dioxide nanoparticles, commonly used as sun protection agents, on microvascular endothelial cells. Journal of Nanoparticle Research, 16:2130.

J Domey, L Haslauer, I Grau, C Strobel, M Kettering, I Hilger (2014). Probing the Cytotoxicity of Nanoparticles: Experimental Pitfalls and Artifacts”. Bioanalytical Reviews, ISSN 1867-2086, DOI: 10.1007/11663_2013_8.

C Strobel, AA Torrano, R Herrmann, M Malissek, C Bräuchle, A Reller, L Treuel, WA Kaiser, I Hilger. Effects of the physicochemical properties of titanium dioxide nanoparticles, commonly used as sun protection agents, on microvascular endothelial cells. Journal of Nanoparticle Research, accepted.

S Kossatz, R Mansi, M Béhé, P Czerney, I Hilger (2013). Influence of d-glutamine and d-glutamic Acid Sequences in Optical Peptide Probes Targeted against the Cholecystokinin-2/gastrin-Receptor on Binding Affinity, Specificity and Pharmacokinetic Properties. European Journal of Nuclear Medicine and Molecular Imaging Research (EJNMMI Research). Volume 3, Issue 1.

I Hilger. In vivo applications of magnetic nanoparticle hyperthermia. Review. International Journal of Hyperthermia 2013, 29:8, 828-834.

K Haedicke, S Gräfe, F Lehmann, I Hilger (2013). Multiplexed in vivo fluorescence optical imaging of the therapeutic efficacy of photodynamic therapy. Biomaterials 34: 10075-10083.

UR Anumala, J Gu, F Lo Monte, T Kramer, R Heyny-von Haußen, J Hölzer, V Goetschy-Meyer, C Schön, G Mall, I Hilger, C Czech, J Herms, B Schmidt (2013). Fluorescent rhodanine-3-acetic acids visualize neurofibrillary tangles in Alzheimer’s disease brains. Bioorganic & Medicinal Chemistry 21: 5139-5144.

J Gu, U Rao Anumala, R Heyny-von Haußen, J Hölzer, V Goetschy-Meyer, G Mall, I Hilger, C Czech, B Schmidt (2013). Design, Synthesis and Biological Evaluation of Trimethine Cyanine Dyes as Fluorescent Probes for the Detection of Tau Fibrils in Alzheimer’s Disease Brain and Olfactory Epithelium. Chem Med Chem 8: 891-897.

R Zellner, J Blechinger, C Bräuchle, I Hilger, A Janshoff, J Lademann, V Mailänder, MC Meinke, GU Nienhaus, A Patzelt, F Rancan, B Rothen-Ruthishauser, RH Stauber, AA Torrano, L Treuel, A Vogt (2013). Biological Responses to Nanomaterials. Chapter 6 in: Safety Aspects of Engineeres Nanomaterials (edited by Wolfgang Luther, Axel Zweck), Pan Stanford Publishing Pte. Ltd (2013-06-30); Print ISBN: 9789814364850; eBook ISBN: 9789814364867, online veröffentlicht im Juni 2013.

I Hilger, K Dahlke, G Rimkus, C Geyer, F Seifert, O Kosch, F Thiel, M Hein, F Scotto di Clemente, U Schwarz, M Helbig, J Sachs (2013). ultraMEDIS - Ultra-Wideband Sensing in Medicine. Chapter 11, Page 257-322. In: Ultra-Wideband Radio Technologies for Communications, Localization and Sensor Applications, Edited by Reiner Thomä, Reinhard H. Knöchel, Jürgen Sachs, Ingolf Willms and Thomas Zwick; INTECH, ISBN 978-953-51-0936-5, gedruckt erschienen im Februar 2013.

FA Gonnert, P Recknagel, I Hilger, RA Claus, M Bauer, A Kortgen (2013). Hepatic excretory function in septic patients: implications from biophotonic analysis of transcellular xenobiotic transport in a rodent model of sepsis. Critical Care 17: R67.

F Tansi, R Rüger, M Rabenhold, F Steiniger, A Fahr, WA Kaiser, I Hilger (2013). Liposomal encapsulation of a near-infrared fluorophore enhances fluorescence quenching and reliable whole body optical imaging upon activation in vivo. Small (doi: 10.1002/smll.201203211).

M Franz, I Hilger, K Grün, S Kossatz, I Petersen, J Gummert, HR Figulla, H Kosmehl, D Neri, A Berndt, A Renner (2013). Selective imaging of chronic cardiac allograft rejection using a human antibody specific to the alternatively spliced ED-A domain of fibronectin. Journal of Heart and Lung Transplantation 32: 641-650.

F Dietzel, MK Boettger, K Dahlke, F Lehmann, M Gajda, R Bräuer, HG Schaible, WA Kaiser, I Hilger (2013). Assessment of rat antigen-induced arthritis and its suppression during glucocorticoid therapy by near-infrared fluorescence (NIRF) optical imaging. Investigative Radiology 48: 729-737.

S Kossatz, M Béhé, R Mansi, D Saur, P Czerney, WA Kaiser, I Hilger (2013). Multifactorial diagnostic NIR imaging of CCK2R expressing tumors. Biomaterials 34: 5172-5180.

K Franke, M Kettering, K Lange, WA Kaiser, I Hilger (2013). The exposure of cancer cells to hyperthermia, iron oxide nanoparticles, and mitomycin C influences membrane multidrug resistance protein (MRP) expression levels. International Journal of Nanomedicine 8: 351-363.

A Boländer, D Kieser, C Voss, S Bauer, C Schön, S Burgold, T Bittner, J Hölzer, R Heyny-von Haußen, G Mall, V Goetschy, C Czech, H Knust, R Berger, J Herms, I Hilger, B Schmidt (2012). Bis(arylvinyl)pyrazines, -pyrimidines and -pyridazines as Imaging Agents for Tau Fibrils and β-Amyloid Plaques in Alzheimer’s Disease Models. J Med Chem 55: 9170-9180.

C Busch, T Schröter, M Grabolle, M Wenzel, H Kempe, WA Kaiser, U Resch-Genger, I Hilger (2012). An In Vivo Spectral Multiplexing Approach for the Cooperative Imaging of Different Disease-Related Biomarkers with Near-Infrared Fluorescent Förster Resonance Energy Transfer Probes. J Nucl Med 53: 638-646.

S Dutz, M Kettering, I Hilger, R Müller, M Zeisberger (2012). Magnetic particle hyperthermia - Properties of magnetic multicore nanoparticles administered to tumor tissue. Konferenzpaper BMT 17.-19.09.2012, Jena, D; Biomed Tech 57: 76.

M Grabolle, R Brehm, J Pauli, FM Hamann, I Hilger, U Resch-Genger (2012). Determination of the Labeling Density of Fluorophore-Biomolecule Conjugates with Absorption Spectroscopy. Bioconjugate Chemistry 23: 287-292.

J Gu, UR Anumala, FL Monte, T Kramer, R Heyny-von Haußen, J Hölzer, V Goetschy-Meyer, G Mall, I Hilger, C Czech, B Schmidt (2012). 2-Styrylindolium based fluorescent probes visualize neurofibrillary tangles in Alzheimer's disease. Bioorganic & Medicinal Chemistry Letters 22: 7667-7671.

M Helbig, K Dahlke, I Hilger, M Kmec, J Sachs (2012). UWB microwave imaging of heterogeneous breast phantoms. Conference Paper 46. GDBMT Jahrestagung, Biomed Tech 57: 486-489.

I Hilger , WA Kaiser (2012). Iron oxide-based nanostructures for MRI and magnetic hyperthermia. Nanomedicine 7: 1443-1459.

I Hilger, WA Kaiser (2012). Potential of near infrared fluorescence optical imaging in diagnostic radiology. European Journal of Radiology 81: 61-62.

G Rimkus, C Grüttner, S Bremer-Streck, KH Herrmann, I Krumbein, JR Reichenbach, M Förster, WA Kaiser, I Hilger (2012). mVCAM-1 specific iron oxide nanoparticle based probes for multimodal imaging purposes. Conference Paper 46. GDBMT Jahrestagung, Biomed Tech 57: 77-80.

M Helbig, K Dahlke, I Hilger, M Kmec, J Sachs (2012). Design and test of an imaging system for UWB breast cancer detection. FREQUENZ DOI 10.1515/freq-2012-0103.

P Recknagel, FA Gonnert, M Westermann, S Lambeck, A Lupp, A Rudiger, A Dyson, JE Carre´, A Kortgen, C Krafft, J Popp, C Sponholz, V Fuhrmann, I Hilger, RA Claus, NC Riedemann, R Wetzker, M Singer, M Trauner, M Bauer (2012). Liver Dysfunction and Phosphatidylinositol-3-Kinase Signalling in Early Sepsis: Experimental Studies in Rodent Models of Peritonitis. PLosMedicine 9: e1001338.

I Hilger (2012). Present and future applicability of magnetic nanoparticles in radiology. In: Nanotechnology, Ed: JN Govil, Vol 7: Diagnostics and Therapeutics (ES Sinha and NK Navani), Studium Press LLC, P.O. Box 722 200, Houston USA, ISBN: 1-62699-007-7.

I Hilger, K Dahlke, G Rimkus, C Geyer, F Seifert, O Kosch, F Thiel, M Hein, FS di Clemente, U Schwarz, M Helbig, J Sachs (2012). ultraMEDIS - Ultra-Wideband Sensing in Medicine. In: Dr.-Ing. RS Thomä, Dr.-Ing. HI Willms, Dr.-Ing. T Zwick, Dr.-Ing. R Knöchel, Dr.-Ing. J Sachs (2012). UKoLoS Ultra-Wideband Radio Technologies for Communications, Localization and Sensor Applications, ISBN 979-953-307-275-2.

C Busch, M Passon, M Wenzel, I Socher, WA Kaiser, I Hilger (2011). Detection of Leukotriene Receptor CysLT1R in Inflammatory Diseases by Molecular Imaging with Near-Infrared Fluorescence (NIRF) Based Contrast Agents. Molecular Imaging 10: 81-90.

S Dutz, M Kettering, I Hilger, R Müller, M Zeisberger (2011). Magnetic multicore nanoparticles for hyperthermia - influence of particle immobilization in tumour tissue on magnetic properties. Nanotechnology 22: 265102.

FM Hamann, R Brehm, J Pauli, M Grabolle, W Frank, WA Kaiser, D Fischer, U Resch-Genger, I Hilger (2011). Controlled modulation of serum protein binding and biodistribution of asymmetric cyanine dyes by variation of the number of sulfonate groups. Molecular Imaging 10: 258-69.

I Hilger, WA Kaiser (2011). Parameters Influencing the Efficacy of Magnetic Heating of Small Breast Tumors. In: C Alexiou: Nanomedicine - Basic and Clinical Applications in Diagnostics and Therapy. Else Kröner-Fresenius Symp. Basel, Karger 2: 165-176.

H Jha, F Schmidt-Stein, NK Shrestha, M Kettering, I Hilger, P Schmuki (2011). Formation of Magnetic Aluminium Oxyhydroxide Nanorods and Use for Hyperthermal Effects. Nanotechnology 22: 115601.

M Kettering, H Richter, F Wiekhorst, S Bremer-Streck, L Trahms, WA Kaiser, I Hilger (2011). Minimal-invasive magnetic heating of tumors does not alter intra-tumoral nanoparticle accumulation, allowing for repeated therapy sessions: An in vivo study in mice. Nanotechnology 22: 505102.

E Laabs, M Béhé, S Kossatz, W Frank, WA Kaiser, I Hilger (2011). Optical Imaging of CCK2/Gastrin Receptor-Positive Tumors With a Minigastrin Near-Intrared Probe. Investigative Radiology 46: 196-201.

J Pauli, M Grabolle, R Brehm, M Spieles, FM Hamann, M Wenzel, I Hilger, U Resch-Genger (2011). Suitable Labels for Molecular Imaging - Influence of Dye Structure and Hydrophilicity of the Spectroscopic Properties of IgG Conjugates. Bioconjugate Chemistry 22: 1298-1308.

J Pauli, R Brehm, M Grabolle, T Behnke, J Mathejczyk, FM Hamann, F Alves, I Hilger, U Resch-Genger (2011). Dye-Biomolecule Conjugates and NIR-Fluorescent Particles for Targeting of Disease-related Biomarkers. Proc. SPIE 7910: 791014.

G Rimkus, S Bremer-Streck, C Grüttner, WA Kaiser, I Hilger (2011). Can we accurately quantify nanoparticle associated proteins when constructing high-affinity MRI molecular imaging probes? CMMI 6: 119-25.

H Berg, B Günther, I Hilger, M Radeva, N Traitcheva, L Wollweber (2010). Bioelectromagnetic Field Effects on Cancer Cells and Mice Tumors. Electromagnetic Biology and Medicine 29: 1-12.

D Eberbeck, M Kettering, C Bergemann, P Zirpel, I Hilger, L Trahms (2010). Quantification of the aggregation of magnetic nanoparticles with different polymeric coatings in cell culture medium. Journal of Physics D: Applied Physics 43: 405002.

M Gottschaldt, US Schubert, S Rau, S Yano, JG Vos, T Kroll, J Clement, I Hilger (2010). Sugar-Selective Enrichment of a D-Glucose-Substituted Ruthenium Bipyridyl Complex Inside HepG2 Cancer Cells. Chembiochem 11: 649-652.

J Pauli, R Brehm, M Spieles, WA Kaiser, I Hilger, U Resch-Genger (2010). Novel Fluorophores as Building Blocks for Optical Probes for In Vivo Near Infrared Fluorescence (NIRF) Imaging. Journal of Fluorescence 20: 681-693.

H Richter, M Kettering, F Wiekhorst, U Steinhoff, I Hilger, L Trahms (2010). Magnetorelaxometry for localization and quantification of magnetic nanoparticles for thermal ablation studies. Phy. Med. Bio. 55: 623-633.

J Pauli, T Vag, R Haag, M Spieles, M Wentzel, WA Kaiser, U Resch-Genger, I Hilger (2009). An in vitro characterization study of new near infrared dyes for molecular imaging. European Journal of Medicinal Chemistry 44: 3496-3503.

T Vag, T Schramm, WA Kaiser, I Hilger (2009). Proliferating and Quiescent Human Umbilical Vein Endothelial Cells (HUVECs): A potential in vitro Model to Evaluate Contrast Agents for Molecular Imaging of Angiogenesis. Contrast Media and Molecular Imaging 4: 192-198.

M Kettering, H Zorn, S Bremer-Streck, H Oehring, M Zeisberger, C Bergemann, R Hergt, KJ Halbhuber, WA Kaiser, I Hilger (2009). Characterization of iron oxide nanoparticles adsorbed with cisplatin for biomedical applications. Phys Med Biol 54: 5109-5121.

I Hilger, C Geyer, U Schwarz, M Helbig, G Rimkus, M Hein, J Sachs, WA Kaiser (2009). Ultra-wideband technology - What is it and could it be used for breast cancer detection? European Radiology 19: 835-841.

F Thiel, M Helbig, U Schwarz, C Geyer, G Rimkus, WA Kaiser, I Hilger, M Hein, J Sachs, F Seifert (2009). Implementation of ultra-wideband sensors for biomedical applications. Frequenz, Journal of RF-Engineering and Telecommunications 63: 221-224.

MR Lisy, A Görmar, J Pauli, U Resch-Genger, WA Kaiser, I Hilger (2008). In vivo near infrared fluorescence imaging of carcinoembryonic antigen expressing tumor cells. Radiology 247: 779-787.

V Deissler, R Rüger, W Frank, A Fahr, WA Kaiser, I Hilger (2008). Fluorescent liposomes as novel contrast agent for in vivo optical imaging of edemas in mice. Small 4: 1240-1246.

KH Herrmann, E Wagner, A Deistung, I Hilger, JR Reichenbach (2008). A robust optical respiratory trigger for small rodents in clinical whole-body MR systems / Ein robuster optischer Atemtrigger für Kleinsäuger in klinischen Ganzkörper-MR-Scannern. Biomed Tech (Berl) 53:138-44.

M Kettering, J Winter, M Zeisberger, S Bremer-Streck, H Oehring, C Bergemann, C Alexiou, R Hergt, KJ Halbhuber, WA Kaiser, I Hilger (2007) Magnetic nanoparticles as bimodal tools in magnetically induced labelling and magnetic heating of tumor cells: an in vitro study. Nanotechnology 18: 175101.

I Hilger, R Trost, JR Reichenbach, W Linss, MR Lisy, A Berndt, WA Kaiser (2007). MR imaging of Her-2/neu protein binding using magnetic nanoparticles. Nanotechnology 18: 135103.

MR Lisy, A Hartung, C Lang, D. Schüler, W Richter; JR Reichenbach, WA Kaiser, I Hilger (2007). Fluorescent bacterial magnetic nanoparticles as bimodal contrast agents. Investigative Radiology 42: 235-241.

A Hartung, MR Lisy, KH Herrmann, I Hilger, D Schüler, C Lang, ME Bellemann, WA Kaiser, JR Reichenbach (2007). Labeling of macrophages using bacterial magnetosomes and their characterization by magnetic resonance imaging. JMMM 311: 454-459.

I Hilger, E Dietmar, W. Linß, S Streck, WA Kaiser (2006). Developments for the minimally invasive treatment of tumours by targeted heating. Journal of Physics: Condensed Matter 18: 2951-2958.

O Brunke, S Odenbach, R Jurgons, C Alexiou, I Hilger, F Beckmann (2006). Determination of the magnetic particle distribution in tumour tissue by means of X-ray tomography. Journal of Physics: Condensed Matter 18: 2903-2917.

MR Lisy, E Schüler, F Lehmann, R Czerney, WA Kaiser, I Hilger (2006). Diagnosis of peritonits using near infrared optical imaging of in vivo labeled monocytes-macrophages. Journal of Biomedical Optics 11: 064014.

M Kettering, J Winter, R Hergt, M Zeisberger, C Alexiou, S Streck, C Bergemann, WA Kaiser, I Hilger (2006). Magnetisch basierte Steigerung der Nanopartikelaufnahme in Tumorzellen: Kombination von magnetisch induzierter Zellmarkierung und magnetischer Wärmebehandlung. RöFo 178: 1255-1260.

I Hilger, WA Kaiser (2006). Molecular imaging of breast cancer. European Radiology 16: E45.

I Hilger, WA Kaiser (2006). Magnetic Thermoablation. European Radiology 16: E47.

O Brunke, S Odenbach, C Fritsche, I Hilger, WA Kaiser (2005). Determination of magnetic particle distribution in biomedical applications by X-ray microtomography. JMMM 289:428-430.

I Hilger, R Hergt, WA Kaiser (2005). Towards breast cancer treatment by magnetic heating. JMMM 293: 314-319.

R Hergt, R Hiergeist, M Zeissberger, D Schüler, U Heyen, I Hilger, WA Kaiser (2005). Magnetic properties of bacterial magnetosomes as potential diagnostic and therapeutic tools. JMMM 293: 80-86.

I Hilger, W Andrä, R Hergt, R Hiergeist, WA Kaiser (2005). Magnetische Thermotherapie der Brust: ein experimenteller Therapieansatz. Fortschr. Röntgenstr. 177: 507-515.

I Hilger, W Andrä, R Hergt, R Hiergeist, WA Kaiser (2004). Review: Magnetic Nanoparticles for Cancer Therapy. In: Inorganic Materials, Recent Advances, D Bahadur, S Vitta, O Prakash (Eds.), New Delhi: Narosa Publishing House, 516-521.

A Hansch, O Frey, D Sauner, I Hilger, M Haas, A Malich, R Bräuer, WA Kaiser (2004). In vivo imaging of experimental arthritis with near-infrared fluorescence (NIRF). Arthritis and Rheumatism 50: 961-967.

R Hergt, R Hiergeist, I Hilger, WA Kaiser, Y Lapatnikov, S Margel, U Richter (2004). Maghemite Nanoparticles with very high ac-losses for application in RF-magnetic hyperthermia. JMMM 270: 345-347.

I Hilger, Y Leistner, A Berndt, C Fritsche, KM Haas, H Kosmehl, WA Kaiser (2004). NIRF-imaging of the HER-2 protein overexpression in tumor cells. European Radiology 14: 1124-1129.

I Hilger, A Kießling, E Romanus, R Hiergeist, R Hergt, W Andrä, M Roskos, W Linss, P Weber, W Weitschies, WA Kaiser (2004). Magnetic nanoparticles for selective detection and heating of magnetically labeled cells in culture. Nanotechnology 15: 1027-1032.

R Hergt, R Hiergeist, M Zeisberger, G Glöckl, W Weitschies, LP Ramirez, I Hilger, WA Kaiser (2004). Enhancement of AC-losses of magnetic nanoparticles for heating applications. J. Magn. Magn. Mater. 280: 358-368.

I Hilger, S Frühauf, W Linß, R Hiergeist, W Andrä, R Hergt, WA Kaiser (2003). Cytotoxicity of selected magnetic ferrofluids on human adenocarcinoma cells. JMMM 261: 7-12.

D May, I Hilger (2003). Magnetische Wärmetherapie bei Brustkrebs. In-vivo-Studien an Mäusen. MTA Dialog 6: 515-517.

A Hansch, D Sauner, I Hilger, O Frey, M Haas, R Bräuer, WA Kaiser (2003). Non-invasive diagnosis of arthritis by autofluorescence. Inv. Radiol. 38: 578-583.

I Hilger, W Andrä, R Hergt, R Hiergeist, WA Kaiser (2003). Minimal-invasive elimination of small tumours in the breast by magnetic heating. Rev. Rec. Res. Radiol 1: 109-125.

I Hilger, K Frühauf, W Andrä, R Hiergeist, R Hergt, WA Kaiser (2002). Heating potential of iron oxides for therapeutic purposes in interventional radiology. Academic Radiology 9: 198-202.

I Hilger, F Hofmann, JR Reichenbach, C Bergemann, R Hiergeist, W Andrä, R Hergt, WA Kaiser (2002). Bildgebende Darstellung von Magnetiten in vitro. Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren 174: 1-3.

I Hilger, R Hiergeist, R Hergt, K Winnefeld, H Schubert, WA Kaiser (2002). Thermoablation of tumors using magnetic nanoparticles: an in vivo feasibility study. Investigative Radiology 37: 580-586.

T Boehm, A Malich, SN Goldberg, JR Reichenbach, I Hilger, M Fleck, WA Kaiser (2002). Radiofrequency tumor ablation: internally-cooled electrode versus saline enhanced technique in a highly aggressive animal tumor model. Radiology 222: 805-813.

R Hergt, R Hiergeist, I Hilger, WA Kaiser (2002). Review: Magnetic Nanoparticles for Thermoablation. Rec Res Devel Mat Sci. 3: 723-742.

I Hilger, W Andrä, R Hergt, R Hiergeist, H Schubert, WA Kaiser (2001). Electromagnetic heating of breast tumors in interventional radiology: in vitro and in vivo studies in human cadavers and mice. Radiology 218: 570-575.

I Hilger, W Andrä, R Hergt, R Hiergeist, WA Kaiser (2001). Treatment of breast cancers by magnetic thermoablation: in vivo experiments in mice. Magnetohydrodynamics 3: 323-327.

I Hilger, S Frühauf, W Andrä, R Hiergeist, R Hergt, WA Kaiser (2001). Magnetic heating as a therapeutic tool. Thermology International 11: 130-131.

T Böhm, A Malich, SN Goldberg, JR Reichenbach, I Hilger, M Fleck, WA Kaiser (2001). Vacuum-assisted resection of malignant tumors with and without subsequent radiofrequency ablation: feasibility of complete tumor treatment tested in an animal model. Journal of Vascular Interventional Radiology 12: 1086-1093.

I Hilger, R Hergt, WA Kaiser (2000). Effects of magnetic thermoablation in muscle tissue using iron oxide particles: an in vitro study. Investigative Radiology 35: 170-179.

T Böhm, I Hilger, W Müller, JR Reichenbach, M Fleck, WA Kaiser (2000). Saline-enhanced radiofrequency ablation of breast tissue: an in vitro feasibility study. Investigative Radiology 35: 149-157.

A Hochmuth, M Fleck, P Hauff, M Reinhardt, H Kosmehl, I Hilger, L Dinkelborg, WA Kaiser (2000). First experiences in using a new ultrasound mode and ultrasound contrast agent in the diagnosis of blunt renal trauma: a feasibility study in an animal model. Investigative Radiology 35: 205-211.

W Andrä, CG d´Ambly, R Hergt, I Hilger, WA Kaiser (1999). Temperature distribution as function of time around a small spherical heat source of local magnetic hyperthermia. Journal of Magnetism and Magnetic Materials 194: 197-203.

R Hiergeist, W Andrä, N Buske, R Hergt, I Hilger, U Richter, WA Kaiser (1999). Application of magnetic ferrofluids for hyperthermia. Journal of Magnetism and Magnetic Materials 201: 420-422.

R Hergt, W Andrä, CG d`Ambly, I Hilger, WA Kaiser, U Richter, HG Schmidt (1998). Physical Limitations of Hyperthermia Using Magnetite Fine Particles. IEEE Transactions on Magnetics 34: 3745-3754.

 Hilger, W Andrä, R Bähring, A Daum, C Grosser, R Hergt, WA Kaiser (1997). Evaluation of temperature increase with different amounts of magnetite in liver tissue samples. Investigative Radiology 32: 705-712.

I Hilger, W Andrä, R Bähring, R Hergt, WA Kaiser (1997). Untersuchungen zur hyperthermischen Behandlung von Tumorgewebe mit Hilfe von Eisen(II,III)-oxid. Biomedizinische Technik 42: 383-384.