2021

High prevalence of long-term olfactory dysfunction confirmed by olfactory testing after a community COVID-19 outbreak.

Gudziol H, Kirschstein T, Pletz MW, Weis S, Guntinas-Lichius O, Bitter T; CoNAN study group. HNO. 2021 Dec 23:1-8. doi: 10.1007/s00106-021-01129-7. Online ahead of print.

Complicated Long Term Vaccine Induced Thrombotic Immune Thrombocytopenia-A Case Report.

Günther A, Brämer D, Pletz MW, Kamradt T, Baumgart S, Mayer TE, Baier M, Autsch A, Mawrin C, Schönborn L, Greinacher A, Thiele T. Vaccines (Basel). 2021 Nov 17;9(11):1344. doi: 10.3390/vaccines9111344.

Identification of a highly efficient dual type I/II FMS-like tyrosine kinase inhibitor that disrupts the growth of leukemic cells.

Beyer M, Henninger SJ, Haehnel PS, Mustafa AM, Gurdal E, Schubert B, Christmann M, Sellmer A, Mahboobi S, Drube S, Sippl W, Kindler T, Krämer OH. Cell Chem Biol. 2021 Nov 9:S2451-9456(21)00475-X. doi: 10.1016/j.chembiol.2021.10.011. Online ahead of print.

Incidence and severity of G6PI-induced arthritis are not increased in genetically distinct mouse strains upon aging.

Andreas N, Müller S, Templin N, Jordan PM, Schuhwerk H, Müller M, Gerstmeier J, Miek L, Andreas S, Werz O, Kamradt T. Arthritis Res Ther. 2021 Aug 24;23(1):222. doi: 10.1186/s13075-021-02596-7.

T cell response after SARS-CoV-2 vaccination in immunocompromised patients with inflammatory bowel disease.

Reuken PA, Andreas N, Grunert PC, Glöckner S, Kamradt T, Stallmach A. J Crohns Colitis. 2021 Aug 11:jjab147. doi: 10.1093/ecco-jcc/jjab147. Online ahead of print.

ATP/IL-33-triggered hyperactivation of mast cells results in an amplified production of pro-inflammatory cytokines and eicosanoids.

Jordan PM, Andreas N, Groth M, Wegner P, Weber F, Jäger U, Küchler C, Werz O, Serfling E, Kamradt T, Dudeck A, Drube S. Immunology. 2021 Nov;164(3):541-554. doi: 10.1111/imm.13386. Epub 2021 Jun 30.

Lasp1 regulates adherens junction dynamics and fibroblast transformation in destructive arthritis.

Beckmann D, Römer-Hillmann A, Krause A, Hansen U, Wehmeyer C, Intemann J, de Gorter DJJ, Dankbar B, Hillen J, Heitzmann M, Begemann I, Galic M, Weinhage T, Foell D, Ai R, Kremerskothen J, Kiener HP, Müller S, Kamradt T, Schröder C, Leitão E, Horsthemke B, Rosenstiel P, Nordström K, Gasparoni G, Gasparoni N, Walter J, Li N, Yang X, Chung HR, Pavenstädt H, Lindemann N, Schnittler HJ, Wang W, Firestein GS, Pap T, Korb-Pap A. Nat Commun. 2021 Jun 15;12(1):3624. doi: 10.1038/s41467-021-23706-8.

Tim-3 is dispensable for allergic inflammation and respiratory tolerance in experimental asthma.

Boehne C, Behrendt AK, Meyer-Bahlburg A, Boettcher M, Drube S, Kamradt T, Hansen G. PLoS One. 2021 Apr 6;16(4):e0249605. doi: 10.1371/journal.pone.0249605. eCollection 2021.

Candida pathogens induce protective mitochondria-associated type I interferon signalling and a damage-driven response in vaginal epithelial cells.

Pekmezovic M, Hovhannisyan H, Gresnigt MS, Iracane E, Oliveira-Pacheco J, Siscar-Lewin S, Seemann E, Qualmann B, Kalkreuter T, Müller S, Kamradt T, Mogavero S, Brunke S, Butler G, Gabaldón T, Hube B. Nat Microbiol. 2021 May;6(5):643-657. doi: 10.1038/s41564-021-00875-2. Epub 2021 Mar 22.

Severe clinical relapse in an immunocompromised host with persistent SARS-CoV-2 infection.

Reuken PA, Stallmach A, Pletz MW, Brandt C, Andreas N, Hahnfeld S, Löffler B, Baumgart S, Kamradt T, Bauer M. Leukemia. 2021 Mar;35(3):920-923. doi: 10.1038/s41375-021-01175-8. Epub 2021 Feb 19.

Targeting transdifferentiated hepatic stellate cells and monitoring the hepatic fibrogenic process by means of IGF2R-specific peptides designed in silico.

Weber F, Casalini T, Valentino G, Brülisauer L, Andreas N, Koeberle A, Kamradt T, Contini A, Luciani P. J Mater Chem B. 2021 Mar 4;9(8):2092-2106. doi: 10.1039/d0tb02372h.

Inhibition of Inducible Nitric Oxide Synthase Prevents IL-1β-Induced Mitochondrial Dysfunction in Human Chondrocytes.

Eitner A, Müller S, König C, Wilharm A, Raab R, Hofmann GO, Kamradt T, Schaible HG. Int J Mol Sci. 2021 Mar 1;22(5):2477. doi: 10.3390/ijms22052477.

IL-3 is essential for ICOS-L stabilization on mast cells, and sustains the IL-33-induced RORγt+ Treg generation via enhanced IL-6 induction.

Drube S, Müller S, Weber F, Wegner P, Böttcher-Loschinski R, Gaestel M, Hutloff A, Kamradt T, Andreas N. Immunology. 2021 May;163(1):86-97. doi: 10.1111/imm.13305. Epub 2021 Jan 27.

Antibody response using six different serological assays in a completely PCR-tested community after a coronavirus disease 2019 outbreak-the CoNAN study.

Weis S, Scherag A, Baier M, Kiehntopf M, Kamradt T, Kolanos S, Ankert J, Glöckner S, Makarewicz O, Hagel S, Bahrs C, Kimmig A, Proquitté H, Guerra J, Rimek D, Löffler B, Pletz MW; CoNAN Study Group. Clin Microbiol Infect. 2021 Mar;27(3):470.e1-470.e9. doi: 10.1016/j.cmi.2020.11.009. Epub 2020 Nov 20.