Molecular Pharmacology

Our research focuses on the following topics:

- Neurogenesis in the olfactory system

- Detection and processing of chemosensory signals

- Cilia in olfactory neurons

- "Ectopic" olfactory receptors

Contact

Tel: +49 3641 93 25 670

Fax. +49 3641 93 25 652

Colleagues

Katja Bornkessel; Ph. D. student	93 25 659
Julia Karius; technican	93 25 659

Funded Projects

DFG: Integrative analysis of olfaction (SPP 1392) Projekt: Role of the scaffolding protein SC9A3R1 in the vomeronasal organ; from protein interactions to the physiology of pheromone detection.
DFG: Significance of chemokines during neurogenesis in the olfactory system.

Pelz T, Drose DR, Fleck D, Henkel B, Ackels T, Spehr M, Neuhaus EM: An ancestral TMEM16 homolog from Dictyostelium discoideum forms a scramblase. ; PLoS One. 2018 Feb 14;13(2):e0191219
Kurtenbach S, Gießl A, Strömberg S, Kremers J, Atorf J, Rasche S, Neuhaus EM, Hervé D, Brandstätter JH, Asan E, Hatt H, Kilimann MW: The BEACH Protein LRBA Promotes the Localization of the Heterotrimeric G-protein Golf to Olfactory Cilia. Sci Rep. 16;7(1):8409, 2017
Henkel, B, Bintig, W, Bhat, SS, Spehr, M, Neuhaus, EM: NHERF1 in Microvilli of Vomeronasal sensory neurons. Chem. Senses 42(1); 25-35, 2017
Gelis L, Jovancevic N, Bechara F, Neuhaus EM, Hatt H: Functional expression of olfactory receptors in human primary melanoma and melanoma metastasis. Exp Dermatol. 26(7); 569-576, 2017
Untiet V, Moeller LM, Ibarra-Soria X, Sánchez-Andrade G, Stricker M, Neuhaus EM, Logan DW, Gensch T, Spehr M: Elevated cytosolic Cl-concentrations in dendritic knobs of mouse vomeronasal sensory neurons. Chem Senses. 41(8), 669-676, 2016
Gelis L, Jovancevik N, Veitinger S, Mandal B, Arndt H-D, Neuhaus EM, Hatt H: Functional characterization of the odorant receptor 51E2 in human melanocytes. J. Biol. Chem. 291(34), 17772-17786; 2016