Zepf, F. D., König, L., Kaiser, A., Ligges, C., Ligges, M., Roessner, V., Banaschewski, T., & Holtmann, M. Beyond NICE: Aktualisierte systematische Übersicht zur Evidenzlage der Pubertätsblockade und Hormongabe bei Minderjährigen mit Geschlechtsdysphorie. Hogrefe eContent Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie, 0(0), null. https://doi.org/10.1024/1422-4917/a000972

Rakers, F., Schleussner, E., Cornelius, A., Kluckow, S., Muth, I., Hoyer, D., Rupprecht, S., Schultze, T., Schiecke, K., Ligges, C., Schwab, M., & Hoyer, H. (2024). Association between prenatal glucocorticoid exposure and adolescent neurodevelopment: An observational follow-up study [Article; Early Access]. Acta Obstetricia et Gynecologica Scandinavica, 11. https://doi.org/10.1111/aogs.14885

Bahrs, C., Weis, S., Kesselmeier, M., Ankert, J., Hagel, S., Beier, S., Maschmann, J., Stallmach, A., Steiner, A., Bauer, M., Behringer, W., Baier, M., Richert, C., Zepf, F., Walter, M., Scherag, A., Kiehntopf, M., Löffler, B., & Pletz, M. W. (2023). Non-patient-related SARS-CoV-2 exposure from colleagues and household members poses the highest infection risk for hospital employees in a German university hospital: follow-up of the prospective Co-HCW seroprevalence study. Infection. https://doi.org/10.1007/s15010-023-01995-z

Jecke, L., & Zepf, F. D. (2023). Delivering transgender-specific knowledge and skills into health and allied health studies and training: a systematic review. European Child & Adolescent Psychiatry. https://doi.org/10.1007/s00787-023-02195-8

Mahfouda, S., Maybery, M., Moore, J., Perry, Y., Strauss, P., Zepf, F., & Lin, A. (2023). Gender non-conformity in childhood and adolescence and mental health through to adulthood: a longitudinal cohort study, 1995–2018. Psychological Medicine, 1-10. doi:10.1017/S0033291723001721

Morandini, H. A. E., Watson, P., Stewart, R. M., Wong, J. W. Y., Rao, P., & Zepf, F. D. (2022). Implication of saturated fats in the aetiology of childhood attention deficit/hyperactivity disorder – A narrative review. Clinical Nutrition ESPEN, 52, 78-85. https://doi.org/https://doi.org/10.1016/j.clnesp.2022.10.004

Ligges. C. & Lehmann, T. (2022). Multiple Case Studies in German Children with Dyslexia: Characterization of Phonological, Auditory, Visual, and Cerebellar Processing on the Group and Individual Levels. Brain Sciences. 12(10):1292. https://doi.org/10.3390/brainsci12101292

Pester, B., Russig, B., Winke, O., Ligges, C., Dachselt, R., & Gumhold, S. (2022). Understanding multi-modal brain network data: an immersive 3D visualization approach. Computers & Graphics. 106, 88-97. https://doi.org/10.1016/j.cag.2022.05.024.

Rakers, F., Schleußner, E., Muth, I., Hoyer, D., Rupprecht, S., Schiecke, K., . . . Ligges, C. (2022). Association between antenatal glucocorticoid exposure and the activity of the stress system, cognition, and behavior in 8 to 9-year-old children: a prospective observational study. Acta Obstetricia et Gynecologica Scandinavica. doi:10.1111/aogs.14386

Boehm, I., Steding, J., Ritschel, F., Geisler, F., King, J.A., Lesch, I., Roessner, V., Zepf, F.D., Ehrlich, S. Acute tryptophan depletion balances altered resting state functional connectivity of the salience network in female patients recovered from anorexia nervosa (accepted for publication). Journal of Psychiatry and Neuroscience.

Ligges, C., Ligges, M., & Gaser, C. (2022). Cross-Sectional Investigation of Brain Volume in Dyslexia. Frontiers in Neurology, 13. doi:10.3389/fneur.2022.847919

Steding, J., Ritschel, F., Boehm, I., Geisler, D., King, J.A., Roessner, V., Smolka, M.N., Zepf, F.D., Ehrlich. S. (2022). The effects of acute tryptophan depletion on instrumental reward learning in anorexia nervosa - an fMRI study. Psychol Med. Mar 28:1-11. doi: 10.1017/S0033291721005493. Epub ahead of print. PMID: 35343412.

Morandini, H.A.E., Rao, P., Hood, S.D., Zepf, F.D., Silk, T.J., Griffiths, K.R. (2021). Age-related resting-state functional connectivity of the Vigilant Attention network in children and adolescents. Brain Cogn. Nov;154:105791. doi: 10.1016/j.bandc.2021.105791. Epub 2021 Sep 9. PMID: 34509772.Copy

Morandini, H.A.E., Rao, P., Hood, S.D., Griffiths, K., Silk, T.J., Zepf, F.D. (2021). Effects of dietary omega-3 intake on vigilant attention and resting-state functional connectivity in neurotypical children and adolescents. Nutr Neurosci. 2021 Aug 9:1-10. doi: 10.1080/1028415X.2021.1955434. Epub ahead of print. PMID: 34369315.

Revet A, Hebebrand J, Anagnostopoulos D, Kehoe LA; COVID-19 Child and Adolescent Psychiatry Consortium, Klauser P. ESCAP CovCAP survey of heads of academic departments to assess the perceived initial (April/May 2020) impact of the COVID-19 pandemic on child and adolescent psychiatry services. Eur Child Adolesc Psychiatry. 2021 Jan 20:1–10. doi: 10.1007/s00787-020-01699-x. Epub ahead of print. PMID: 33474653; PMCID: PMC7816838.

Bahrs C, Kimmig A, Weis S, Ankert J, Hagel S, Maschmann J, Stallmach A, Steiner A, Bauer M, Behringer W, Baier M, Kesselmeier M, Richert C, Zepf F, Walter M, Scherag A, Kiehntopf M, Löffler B, Pletz MW. Prospective surveillance study in a 1,400-bed university hospital: COVID-19 exposure at home was the main risk factor for SARS-CoV-2 point seroprevalence among hospital staff. Transbound Emerg Dis. 2021 Feb 19:10.1111/tbed.14041. doi: 10.1111/tbed.14041. Epub ahead of print. PMID: 33605549; PMCID: PMC8014017.

Yu X, Liu L, Chen W, Cao Q, Zepf FD, Ji G, Wu Z, An L, Wang P, Qian Q, Zang Y, Sun L, Wang Y. Integrity of Amygdala Subregion-Based Functional Networks and Emotional Lability in Drug-Naïve Boys With ADHD. J Atten Disord. 2020 Oct;24(12):1661-1673. doi: 10.1177/1087054716661419. Epub 2016 Aug 8. PMID: 27503948.

Rao P, Caunt JN, Wong JWY, Moore JK, Zepf FD. Child and adolescent psychiatry training in Australia and New Zealand. Eur Child Adolesc Psychiatry. 2020 Jan;29(1):95-103. doi: 10.1007/s00787-019-01422-5. Epub 2019 Oct 22. PubMed PMID: 31641901.

Bär KJ, Köhler S, Cruz F, Schumann A, Zepf FD, Wagner G. Functional consequences of acute tryptophan depletion on raphe nuclei connectivity and network organization in healthy women. Neuroimage. 2020 Feb 15;207:116362. doi:10.1016/j.neuroimage.2019.116362. Epub 2019 Nov 16. PubMed PMID: 31743788.

Stewart RM, Wong JWY, Mahfouda S, Morandini HAE, Rao P, Runions KC, Zepf, FD (2020). Acute Tryptophan Depletion Moja-De: A Method to Study Central Nervous Serotonin Function in Children and Adolescents. Frontiers in Psychiatry, 10(1007). doi: 10.3389/fpsyt.2019.01007

Morandini, HAE, Silk, TJ, Griffiths, K, Rao, P, Hood, S & Zepf, FD (2020). Meta-analysis of the neural correlates of vigilant attention in children and adolescents. Cortex. doi:https://doi.org/10.1016/j.cortex.2020.08.008

Zepf, FD (2020). Thema: Kinder- und Jugendpsychiatrie, Psychosomatik und Psychotherapie. Thüringer Ärzteblatt, 9, 13.

Zepf, FD, Ligges, C, & Ligges, M (2020). Kinder- und Jugendpsychiatrie, Psychosomatik und Psychotherapie in Zeiten der Corona-Pandemie. Thüringer Ärzteblatt, 14-17.

Ligges, M, Ligges, C, Schönberg, A, & Zepf, FD (2020). Darstellung eines Spezialambulanzkonzeptes für Kinder und Jugendliche, die sich als TransGender identifizieren: das Spannungsfeld zwischen Entpathologisierung, klinischer Versorgungsrealität und rechtlichen Vorgaben. Thüringer Ärzteblatt, 9, 18-22.

Ligges, C, & Zepf, FD (2020). Lese-Rechtschreibstörung (LRS): der Weg zur Diagnose in Thüringen, und was kommt danach? Familien im Spannungsfeld der Krankenkassen, schulischen sowie sozialrechtlichen Regelungen. Thüringer Ärzteblatt, 9, 23-26.

Bockhorn, N, Walter, M, & Zepf, FD (2020). Das Konzept der Adoleszenzpsychiatrie – eine Perspektive für die Zukunft. Thüringer Ärzteblatt, 9.

Runions, K. C., Morandini, H. A. E., Rao, P., Wong, J. W. Y., Kolla, N. J., Pace, G., Mahfouda, S., Hildebrandt, C. S., Stewart, R., Zepf, F. D. (2019). Serotonin and aggressive behaviour in children and adolescents: a systematic review. Acta Psychiatr Scand, 139(2), 117-144. doi: 10.1111/acps.12986

Stewart, R. M., Wong, J. W., Mahfouda, S., Morandini, H. A., Runions, K. C., & Zepf, F. D. (2019). Acute Tryptophan Depletion Moja-De: A method to study central nervous serotonin function. Frontiers in Psychiatry: Child and Adolescent Psychiatry. doi: doi: 10.3389/fpsyt.2019.01007

Manchia, M., Booij, L., Pinna, F., Wong, J., Zepf, F., & Comai, St. (2019). Neurobiology of Violence. In B. Carpiniello, A. Vita & C. Mencacci (Eds.), Violence and Mental Disorders (pp. 25-47): Springer International Publishing.

Mahfouda, Simone, Panos, Christina, Whitehouse, Andrew J.O., Thomas, Cati S., Maybery, Murray, Strauss, Penelope, Zepf, Florian D., O’Donovan, Amanda, van Hall, Hans-Willem, Saunders, Liz A., Moore, Julia K., Lin, Ashleigh. (2019). Mental Health Correlates of Autism Spectrum Disorder in Gender Diverse Young People: Evidence from a Specialised Child and Adolescent Gender Clinic in Australia. Journal of Clinical Medicine, 8(10), 1503.

Königschulte, E., Civai, C., Hildebrand, P., Gaber, T. J., Fink, G. R. & F. D. Zepf (2019): Effects of serotonin depletion and dopamine depletion on bimodal divided attention, The World Journal of Biological Psychiatry, DOI: 10.1080/15622975.2018.1532110

Zepf FD, Bubenzer-Busch S, Runions KC, Rao P, Wong JWY, Mahfouda S, Morandini HAE, Stewart RM, Moore JK, Biskup CS, Eickhoff SB, Fink GR, Langner R. Functional connectivity of the vigilant-attention network in children and adolescents with attention-deficit/hyperactivity disorder. Brain Cogn. 2019 Apr;131:56-65. doi: 10.1016/j.bandc.2017.10.005. Epub 2017 Nov 14. PubMed PMID: 29150311; PubMed Central PMCID: PMC6432906.

Hildebrandt CS, Helmbold K, Linden M, Langen KJ, Filss CP, Runions KC, Stewart RM, Rao P, Moore JK, Mahfouda S, Morandini HAE, Wong JWY, Rink L, Zepf FD. No detectable effects of acute tryptophan depletion on short-term immune system cytokine levels in healthy adults. World J Biol Psychiatry. 2019 Jun;20(5):416-423. doi: 10.1080/15622975.2018.1428357. Epub 2018 Apr 26. PubMed PMID: 29353534.

Gensthaler, A., Dieter, J., Raisig, S., Hartmann, B., Ligges, M., Kaess, M., Freitag, C. M., & Schwenck, C. (2018). Evaluation of a Novel Parent-Rated Scale for Selective Mutism. Assessment. doi:10.1177/1073191118787328

Hildebrandt, C. S., Helmbold, K., Linden, M., Langen, K. J., Filss, C. P., Runions, K. C., Stewart, R. M., Rao, P., Moore, J. K., Mahfouda, S., Morandini, H. A. E., Wong, J. W. Y., Rink, L., & Zepf, F. D. (2018). No detectable effects of acute tryptophan depletion on short-term immune system cytokine levels in healthy adults. World J Biol Psychiatry, 1-8. doi:10.1080/15622975.2018.1428357

Klasen, M., Wolf, D., Eisner, P. D., Habel, U., Repple, J., Vernaleken, I., Schluter, T., Eggermann, T., Zerres, K., Zepf, F. D., & Mathiak, K. (2018). Neural networks underlying trait aggression depend on MAOA gene alleles. Brain Structure & Function, 223(2), 873-881. doi:10.1007/s00429-017-1528-6

Konigschulte, W., Civai, C., Hildebrand, P., Gaber, T. J., Fink, G. R., & Zepf, F. D. (2018). Effects of serotonin depletion and dopamine depletion on bimodal divided attention. World J Biol Psychiatry, 1-37. doi:10.1080/15622975.2018.1532110

Leistritz, L., & Ligges, C. (2018). Signal-Adaptive Denoising Of Event-Related Potentials. Conf Proc IEEE Eng Med Biol Soc, 2018, 3096-3099. doi:10.1109/embc.2018.8512940

Mahfouda, S., Moore, J. K., Siafarikas, A., Hewitt, T., Ganti, U., Lin, A., & Zepf, F. D. (2018). Gender-affirming hormones and surgery in transgender children and adolescents. Lancet Diabetes Endocrinol. doi:10.1016/s2213-8587(18)30305-x

Pester, B., Lehmann, T., Leistritz, L., Witte, H., & Ligges, C. (2018). Influence of imputation strategies on the identification of brain functional connectivity networks. J Neurosci Methods, 309, 199-207. doi:10.1016/j.jneumeth.2018.09.021

Pester, B., & Ligges, C. (2018, 18-21 July 2018). Does independent component analysis influence EEG connectivity analyses? Paper presented at the 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

Stewart, R. M., Hood, S. D., Rao, P., Moore, J. K., Runions, K. C., Murphy, S. E., Wong, J. W. Y., & Zepf, F. D. (2018). Using acute tryptophan depletion to investigate predictors of treatment response in adolescents with major depressive disorder: study protocol for a randomised controlled trial. Trials, 19, 9. doi:10.1186/s13063-018-2791-4

Wang, B., Eastwood, P. R., Becker, A., Isensee, C., Wong, J. W. Y., Huang, R. C., Runions, K. C., Stewart, R. M., Meyer, T., Bruni, L. G., Rothenberger, A., & Zepf, F. D. (2018). Concurrent Developmental Course of Sleep Problems and Emotional/behavioral Problems in Childhood and Adolescence as Reflected by the Dysregulation Profile. Sleep. doi:10.1093/sleep/zsy243

Wolf, D., Klasen, M., Eisner, P., Zepf, F. D., Zvyagintsev, M., Palomero-Gallagher, N., Weber, R., Eisert, A., & Mathiak, K. (2018). Central serotonin modulates neural responses to virtual violent actions in emotion regulation networks. Brain Structure & Function, 223(7), 3327-3345. doi:10.1007/s00429-018-1693-2

Wong, J. W. Y., Morandini, H. A. E., Dingerkus, V. L. S., Gaber, T. J., Runions, K. C., Rao, P., Mahfouda, S., Helmbold, K., Bubenzer-Busch, S., Koenemann, R., Stewart, R. M., & Zepf, F. D. (2018). Effects of Dietary Acute Tryptophan Depletion (ATD) on NPY Serum Levels in Healthy Adult Humans Whilst Controlling for Methionine SupplyA Pilot Study. Nutrients, 10(5), 12. doi:10.3390/nu10050594

Schüler, I., Bock, B., Heinrich-Weltzien, R., Bekes, K., Rudovsky, M., Filz, C., & Ligges, C. (2017). Status and perception of oral health in 6–17-year-old psychiatric inpatients—randomized controlled trial. Clinical Oral Investigations, 1-11. doi:10.1007/s00784-017-2077-3

Gensthaler, A., Khalaf, S., Ligges, M., Kaess, M., Freitag, Ch., & Schwenck, Ch. (2016). Selective mutism and temperament: the silence and behavioral inhibition to the unfamiliar. European Child & Adolescent Psychiatry, 1-8. doi: 10.1007/s00787-016-0835-4

Gensthaler A., Maichrowitz V., Kaess M., Ligges M., Freitag C.M., Schwenck C. (2016): Selective Mutism: The Fraternal Twin of Childhood Social Phobia. Selective Mutism: The Fraternal Twin of Childhood Social Phobia. Psychopathology. doi: 10.1159/000444882

Gerhard U.-J., Schönberg A. (2016). Die Anfänge einer differenzierten Neuropsychopharmakotherapie bei Kindern und Jugendlichen. Untersuchung zur Psycho- und Neuropharmakologie in den 40er und 50er Jahren des vorigen Jahrhunderts. Die Anfänge einer differenzierten Neuropsychopharmakotherapie bei Kindern und Jugendlichen. Untersuchung zur Psycho- und Neuropharmakologie in den 40er und 50er Jahren des vorigen Jahrhunderts. Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie. DOI: 10.1024/1422-4917/a000414.

* Pester, B., Ligges, C., Leistritz, L., Witte, H., & Schiecke, K. (2015). Advanced Insights into Functional Brain Connectivity by Combining Tensor Decomposition and Partial Directed Coherence. PLoS One, 10(6), e0129293. doi: 10.1371/journal.pone.0129293

Inhalt

Inhalt

Burkhardt, J., Kirsten, H., Holland, H., Krupp, W., Ligges, C., Quente, E., Boltze, J., Ahnert, P. & Wilcke, A. (2012). Association of rs2069459 in the CDK5 gene with dyslexia in a German cohort. Psychiatric Genetics, 22(6), 307-308.

Halbleib, A., Gratkowski, M., Schwab, K., Ligges, C., Witte, H. & Haueisen, J. (2012). Topographic Analysis of Engagement and Disengagement of Neural Oscillators in Photic Driving: A Combined Electroencephalogram/Magnetoencephalogram Study. Journal of Clinical Neurophysiology, 29(1), 33-41.

Kirsten, H., Wilcke, A., Ligges, C., Boltze, J. & Ahnert, P. (2012). Association study of a functional genetic variant in KIAA0319 in German dyslexics. Psychiatric Genetics, 22(4), 216-217.

* Wilcke, A., Ligges, C., Burkhardt, J., Alexander, M., Wolf, C., Quente, E., Ahnert, P., Hoffmann, P., Becker, A., Muller-Myhsok, B., Cichon, S., Boltze, J. & Kirsten, H. (2012). Imaging genetics of FOXP2 in dyslexia. European Journal of Human Genetics, 20(2), 224-229.

Wacker, M., Galicki, M., Putsche, P., Milde, T., Schwab, K., Haueisen, J., Ligges, C. & Witte, H. (2011). A Time-Variant Processing Approach for the Analysis of Alpha and Gamma MEG Oscillations During Flicker Stimulus Generated Entrainment. Ieee Transactions on Biomedical Engineering, 58(11), 3069-3077.

* Ligges, C., Ungureanu, M., Ligges, M., Blanz, B. & Witte, H. (2010). Understanding the time variant connectivity of the language network in developmental dyslexia: new insights using Granger causality. Journal of Neural Transmission, 117(4), 529-543.

Witte, H., Ungureanu, M., Ligges, C., Hemmelmann, D., Wustenberg, T., Reichenbach, J., Astolfi, L., Babiloni, F. & Leistritz, L. (2009). Signal Informatics as an Advanced Integrative Concept in the Framework of Medical Informatics New Trends Demonstrated by Examples Derived from Neuroscience. Methods of Information in Medicine, 48(1), 18-28.

Inhalt

Ligges, C. & Blanz, B. (2007). Survey of fMRI results regarding a phonological deficit in children and adults with dyslexia: Fundamental deficit or indication of compensation? Zeitschrift Fur Kinder-Und Jugendpsychiatrie Und Psychotherapie, 35(2), 107-117.

Schwab, K., Ligges, C., Jungmann, T., Hilgenfeld, B., Haueisen, J. & Witte, H. (2006). Alpha entrainment in human electroencephalogram and magnetoencephalogram recordings. Neuroreport, 17(17), 1829-1833.

Schönberg, A., Gerhard, U-J, Klemm; S., Ligges, M., Ligges, C. & Blanz, B. (2005). Aktuelle Hirnforschung in der Kinder- und Jugendpsychiatrie - Mögliche Konsequenzen für die Praxis. Ärzteblatt Thüringen. 16 (10): 476-480.

Grünling, C., Ligges, M., Huonker, R., Klingert, M., Witte, H. & Blanz, B. (2004) Dyslexia: the benefit of multimodal integration of fMRI- and EEG-data. Journal of Neural Transmission - Biological Child and Adolescent Psychiatry. 111 (7): 951-969.

Georgiewa, P., Grünling, C., Ligges, M., Filz, C., Moller, U. & Blanz, B. (2004). Age dependent changes in phonological reading in dyslexia. Zeitschrift für Klinische Psychologie und Psychotherapie, 33 (4): 281-289.

Ligges, M., Grünling, C., Rothe, E. & Blanz, B. (2004): Symptomatik, Ursachen und Therapie der Lese-Rechtschreibstörung. Thüringer Ärzteblatt, 15 (3): 118-124.

Rothe, E., Grünling, C., Ligges, M., Fackelmann, J. & Blanz, B. (2004). First effects of training phonological awareness in two age cohorts of kindergarten children. Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie. 32 (3): 167-176.

Inhalt

Möller, U., Ligges, M., Georgiewa, P., Grünling, C., Kaiser, W. A., Blanz, B. & Witte, H. (2002). How to avoid spurious cluster validation? A methodological investigation on simulated and fMRI data. NeuroImage. 17 (1): 431-446.

Möller, U., Ligges, M., Grünling, C., Georgiewa, P., Kaiser, W.A., Witte, H., Blanz, B. (2001): Pitfalls in the clustering of neuroimage data and improvements by global optimization strategies. NeuroImage. 14 (1): 206-218.

Möller, U., Ligges, M., Grünling, C., Georgiewa, P., Blanz, B., Witte, H.: Vorteile globaler Optimierungsstrategien bei der unüberwachten Auswertung medizinischer Bilddaten mittels Clusteranalyse am Beispiel des fMRI. In: Handels, H, Horsch, A., Lehmann, T., Meinzer, H.-P. (Hrsg.): Bildverarbeitung für die Medizin 2001. Algorithmen, Systeme, Anwendungen. Reihe Informatik aktuell, Springer-Verlag Berlin, 2001, S. 247-251.

Ligges, C. (2011). Neuronale Netzwerkaktivität bei der Lese-Rechtschreibstörung. In G. Schulte-Körne (Ed.), Legasthenie und Dyskalkulie: Stärken erkennen - Stärken fördern (pp. 77-86). Bochum: Verlag Dr. Dieter Winkler.

Ligges, C. (2007). Die Bedeutung der Phonologie für die Lese-Rechtschreibstörung. In G. Schulte-Körne (Ed.), Legasthenie und Dyskalkulie: Aktuelle Entwicklungen in Wissenschaft, Schule und Gesellschaft. Bochum: Verlag Dr. Dieter Winkler.

Hellrung, H., Weiler, H.-T., Grünling, C., Ligges, M. & Blanz, B. (2003). Exekutive Funktionen bei Kindern mit einer Aufmerksamkeitsdefizit-/ Hyperaktivitätsstörung - eine fMRT-Studie. In U. Lehmkuhl (Hrsg.). Psychotherapie und Psychopharmakotherapie im Kindes- und Jugendalter. Indikation, Effekte, Verlauf. Berlin: Vandenhoeck & Ruprecht.

Möller, U., Ligges, M., Grünling, C., Georgiewa, P., Blanz, B., Witte, H.: Zur Objektivität explorativer Bildstrukturerkennung mittels Clustering: Fehlerquellen und deren Vermeidung. In: Bildverarbeitung für die Medizin 2002. Algorithmen, Systeme, Anwendungen. Reihe Informatik aktuell, Springer-Verlag Berlin, 342-345.