2024
Ambrożek-Latecka M, Kozlowski P, Hoser G, Bandyszewska M, Hanusek K, Nowis D, Gołąb J, Grzanka M, Piekiełko-Witkowska A, Schulz L, Hornung F, Deinhardt-Emmer S, Kozlowska E, Skirecki T. SARS-CoV-2 and its ORF3a, E and M viroporins activate inflammasome in human macrophages and induce of IL-1α in pulmonary epithelial and endothelial cells. Cell Death Discov. 2024 Apr 25;10(1):191. doi: 10.1038/s41420-024-01966-9. PMID: 38664396; PMCID: PMC11045860.
Boattini M, Bianco G, Llorente LI, Acero LA, Nunes D, Seruca M, Mendes VS, Almeida A, Bastos P, Rodríguez-Villodres Á, Gascón AG, Halperin AV, Cantón R, Escartín MNL, González-López JJ, Floch P, Massip C, Chainier D, Barraud O, Dortet L, Cuzon G, Zancanaro C, Mizrahi A, Schade R, Rasmussen AN, Schønning K, Hamprecht A, Schaffarczyk L, Glöckner S, Rödel J, Kristóf K, Balonyi Á, Mancini S, Quiblier C, Fasciana T, Giammanco A, Paglietti B, Rubino S, Budimir A, Bedenić B, Rubic Z, Marinović J, Gartzonika K, Christaki E, Mavromanolaki VE, Maraki S, Yalçın TY, Azap ÖK, Licker M, Musuroi C, Talapan D, Vrancianu CO, Comini S, Zalas-Więcek P, Michalska A, Cavallo R, Melo Cristino J, Costa C. Enterobacterales carrying chromosomal AmpC β-lactamases in Europe (EuESCPM): Epidemiology and antimicrobial resistance burden from a cohort of 27 hospitals, 2020-2022. Int J Antimicrob Agents. 2024 May;63(5):107115. doi: 10.1016/j.ijantimicag.2024.107115. Epub 2024 Feb 16. PMID: 38367844.
Deinhardt-Emmer S, Deshpande S, Kitazawa K, Herman AB, Bons J, Rose JP, Kumar PA, Anerillas C, Neri F, Ciotlos S, Perez K, Köse-Vogel N, Häder A, Abdelmohsen K, Löffler B, Gorospe M, Desprez PY, Melov S, Furman D, Schilling B, Campisi J. Role of the Senescence-Associated Factor Dipeptidyl Peptidase 4 in the Pathogenesis of SARS-CoV-2 Infection. Aging Dis. 2024 May 7;15(3):1398-1415. doi: 10.14336/AD.2023.0812. PMID: 37728586; PMCID: PMC11081172.
Iffland A, Zechel M, Lewejohann JC, Edel B, Hagel S, Hartmann M, Löffler B, Rödel J. Experience with PCR Testing for Enteric Bacteria and Viruses of Emergency Department Patients with Acute Gastroenteritis: Are There Implications for the Early Treatment of Clostridioides difficile Infection? Antibiotics (Basel). 2024 Mar 6;13(3):243. doi: 10.3390/antibiotics13030243. PMID: 38534678; PMCID: PMC10967468.
König S, Schroeder J, Nietzsche S, Heinekamp T, Brakhage AA, Zell R, Löffler B, Ehrhardt C. The influenza A virus promotes fungal growth of Aspergillus fumigatus via direct interaction in vitro. Microbes Infect. 2024 Mar-Apr;26(3):105264. doi: 10.1016/j.micinf.2023.105264. Epub 2023 Nov 24. PMID: 38008399.
Mandal S, Tannert A, Löffler B, Neugebauer U, Silva LB. Findaureus: An open-source application for locating Staphylococcus aureus in fluorescence-labelled infected bone tissue slices. PLoS One. 2024 Jan 31;19(1):e0296854. doi: 10.1371/journal.pone.0296854. PMID: 38295056; PMCID: PMC10830009.
Timme S, Wendler S, Klassert TE, Saraiva JP, da Rocha UN, Wittchen M, Schramm S, Ehricht R, Monecke S, Edel B, Rödel J, Löffler B, Ramirez MS, Slevogt H, Figge MT, Tuchscherr L. Competitive inhibition and mutualistic growth in co-infections: deciphering Staphylococcus aureus-Acinetobacter baumannii interaction dynamics. ISME Commun. 2024 Jun 10;4(1):ycae077. doi: 10.1093/ismeco/ycae077. PMID: 38962494; PMCID: PMC11221087.
Kremser M, Weiss N, Kaufmann-Stoeck A, Vierbaum L, Kappler S, Schellenberg I, Hiergeist A, Fingerle V, Baier M, Reischl U. Longitudinal analysis of 20 Years of external quality assurance schemes for PCR/NAAT-based bacterial genome detection in diagnostic testing. Front Mol Biosci. 2024 Mar 27;11:1373114. doi: 10.3389/fmolb.2024.1373114. PMID: 38601324; PMCID: PMC11004257.
Kosenkow J, Ankert J, Baier M, Kesselmeier M, Pletz MW. COVID-19 outbreak among employees of a German hospital: risk factor analysis based on a follow-up questionnaire and seroprevalence. Infection. 2024 Mar 15. doi: 10.1007/s15010-024-02220-1. Epub ahead of print. PMID: 38488974.
Bandyszewska M, Ambrożek-Latecka M, Hoser G, Grzanka M, Hornung F, Deinhardt-Emmer S, Skirecki T. SARS-CoV-2 virus-like particle variants alpha and delta mimic the native viruses in their differential inflammasome activating potential. Antiviral Res. 2024 Apr;224:105857. doi: 10.1016/j.antiviral.2024.105857. Epub 2024 Mar 5. PMID: 38453031.
Schellong P, Wennek-Klose J, Spiegel C, Rödel J, Hagel S. Successful outpatient parenteral antibiotic therapy with cefiderocol for osteomyelitis caused by multi-drug resistant Gram-negative bacteria: a case report. JAC Antimicrob Resist. 2024 Feb 7;6(1):dlae015. doi: 10.1093/jacamr/dlae015. PMID: 38328266; PMCID: PMC10848891.
Tuchscherr L, Wendler S, Santhanam R, Priese J, Reissig A, Müller E, Ali R, Müller S, Löffler B, Monecke S, Ehricht R, Guntinas-Lichius O. Reduced Glycolysis and Cytotoxicity in Staphylococcus aureus Isolates from Chronic Rhinosinusitis as Strategies for Host Adaptation. Int J Mol Sci. 2024 Feb 13;25(4):2229. doi: 10.3390/ijms25042229. PMID: 38396905; PMCID: PMC10888669.
Wahl A, Fischer MA, Klaper K, Müller A, Borgmann S, Friesen J, Hunfeld KP, Ilmberger A, Kolbe-Busch S, Kresken M, Lippmann N, Lübbert C, Marschner M, Neumann B, Pfennigwerth N, Probst-Kepper M, Rödel J, Schulze MH, Zautner AE, Werner G, Pfeifer Y. Presence of hypervirulence-associated determinants in Klebsiella pneumoniae from hospitalised patients in Germany. Int J Med Microbiol. 2024 Mar;314:151601. doi: 10.1016/j.ijmm.2024.151601. Epub 2024 Feb 8. PMID: 38359735.
Jordan PM, Günther K, Nischang V, Ning Y, Deinhardt-Emmer S, Ehrhardt C, Werz O. Influenza A virus selectively elevates prostaglandin E2 formation in pro-resolving macrophages. iScience. 2023 Dec 26;27(1):108775. doi: 10.1016/j.isci.2023.108775. PMID: 38261967; PMCID: PMC10797193.
2023
Schaumburg F, Löffler B, Becker K. Closer Interdisciplinary Networking Is Important. Dtsch Arztebl Int. 2023 May 30;120(21):375. doi: 10.3238/arztebl.m2023.0022. PMID: 37530053.
Egerer R, Edel B, Hornung F, Deinhardt-Emmer S, Baier M, Lewejohann JC, Pfister W, Löffler B, Rödel J. SARS-CoV-2 Testing of Emergency Department Patients Using cobas® Liat® and eazyplex® Rapid Molecular Assays. Diagnostics (Basel). 2023 Jul 1;13(13):2245. doi: 10.3390/diagnostics13132245. PMID: 37443639; PMCID: PMC10341290.
Rödel J, Pfeifer Y, Fischer MA, Edel B, Stoll S, Pfister W, Löffler B. Screening of Klebsiella pneumoniae Isolates for Carbapenemase and Hypervirulence-Associated Genes by Combining the Eazyplex® Superbug CRE and hvKp Assays. Antibiotics (Basel). 2023 May 25;12(6):959. doi: 10.3390/antibiotics12060959. PMID: 37370278; PMCID: PMC10294845.
Pahlow S, Richard-Lacroix M, Hornung F, Köse-Vogel N, Mayerhöfer TG, Hniopek J, Ryabchykov O, Bocklitz T, Weber K, Ehricht R, Löffler B, Deinhardt-Emmer S, Popp J. Simple, Fast and Convenient Magnetic Bead-Based Sample Preparation for Detecting Viruses via Raman-Spectroscopy. Biosensors (Basel). 2023 May 30;13(6):594. doi: 10.3390/bios13060594. PMID: 37366959; PMCID: PMC10296004.
Mandal S, Tannert A, Ebert C, Guliev RR, Ozegowski Y, Carvalho L, Wildemann B, Eiserloh S, Coldewey SM, Löffler B, Bastião Silva L, Hoerr V, Tuchscherr L, Neugebauer U. Insights into S. aureus-Induced Bone Deformation in a Mouse Model of Chronic Osteomyelitis Using Fluorescence and Raman Imaging. Int J Mol Sci. 2023 Jun 5;24(11):9762. doi: 10.3390/ijms24119762. PMID: 37298718; PMCID: PMC10254067.
Häder A, Köse-Vogel N, Schulz L, Mlynska L, Hornung F, Hagel S, Teichgräber U, Lang SM, Pletz MW, Saux CJL, Löffler B, Deinhardt-Emmer S. Respiratory Infections in the Aging Lung: Implications for Diagnosis, Therapy, and Prevention. Aging Dis. 2023 Aug 1;14(4):1091-1104. doi: 10.14336/AD.2023.0329. PMID: 37163442; PMCID: PMC10389836.
Schulz L, Hornung F, Häder A, Radosa L, Brakhage AA, Löffler B, Deinhardt-Emmer S. Influenza Virus-Induced Paracrine Cellular Senescence of the Lung Contributes to Enhanced Viral Load. Aging Dis. 2023 Aug 1;14(4):1331-1348. doi: 10.14336/AD.2023.0310. PMID: 37163429; PMCID: PMC10389813.
Maurer M, Klassert TE, Löffler B, Slevogt H, Tuchscherr L. Extraction of High-Quality RNA from S. aureus Internalized by Endothelial Cells. Microorganisms. 2023 Apr 13;11(4):1020. doi: 10.3390/microorganisms11041020. PMID: 37110443; PMCID: PMC10143013.
Pletz MW, Steiner A, Kesselmeier M, Löffler B, Maschmann J, Stallmach A, Trommer S. Introduction of mandatory masking in health care and community: experience from Jena, Germany. Infection. 2023 Apr 3:1–4. doi: 10.1007/s15010-023-02015-w. Epub ahead of print. PMID: 37010806; PMCID: PMC10068697.
Jia LJ, Rafiq M, Radosa L, Hortschansky P, Cunha C, Cseresnyés Z, Krüger T, Schmidt F, Heinekamp T, Straßburger M, Löffler B, Doenst T, Lacerda JF, Campos A Jr, Figge MT, Carvalho A, Kniemeyer O, Brakhage AA. Aspergillus fumigatus hijacks human p11 to redirect fungal-containing phagosomes to non-degradative pathway. Cell Host Microbe. 2023 Mar 8;31(3):373-388.e10. doi: 10.1016/j.chom.2023.02.002. PMID: 36893734; PMCID: PMC10016320.
Edel B, Glöckner S, Stoll S, Lindig N, Boden K, Wassill L, Simon S, Löffler B, Rödel J. Development of a rapid diagnostic test based on loop-mediated isothermal amplification to identify the most frequent non-typhoidal Salmonella serovars from culture. Eur J Clin Microbiol Infect Dis. 2023 Apr;42(4):461-470. doi: 10.1007/s10096-023-04571-3. Epub 2023 Feb 22. PMID: 36810725; PMCID: PMC9998568.
Bahrs C, Weis S, Kesselmeier M, Ankert J, Hagel S, Beier S, Maschmann J, Stallmach A, Steiner A, Bauer M, Behringer W, Baier M, Richert C, Zepf F, Walter M, Scherag A, Kiehntopf M, Löffler B, Pletz MW. Non-patient-related SARS-CoV-2 exposure from colleagues and household members poses the highest infection risk for hospital employees in a German university hospital: follow-up of the prospective Co-HCW seroprevalence study. Infection. 2023 Aug;51(4):1051-1059. doi: 10.1007/s15010-023-01995-z. Epub 2023 Feb 15. PMID: 36788173; PMCID: PMC9928590.
Schnizer C, Andreas N, Vivas W, Kamradt T, Baier M, Kiehntopf M, Glöckner S, Scherag A, Löffler B, Kolanos S, Guerra J, Pletz MW, Weis S. Persistent humoral and CD4+ TH cell immunity after mild SARS-COV-2 infection-The CoNAN long-term study. Front Immunol. 2023 Jan 13;13:1095129. doi: 10.3389/fimmu.2022.1095129. PMID: 36713390; PMCID: PMC9880277.
Oberbach A, Schlichting N, Hagl C, Lehmann S, Kullnick Y, Friedrich M, Köhl U, Horn F, Kumbhari V, Löffler B, Schmidt F, Joskowiak D, Born F, Saha S, Bagaev E. Four decades of experience of prosthetic valve endocarditis reflect a high variety of diverse pathogens. Cardiovasc Res. 2023 Mar 31;119(2):410-428. doi: 10.1093/cvr/cvac055. PMID: 35420122.
2022
Pistiki A, Hornung F, Silge A, Ramoji A, Ryabchykov O, Bocklitz TW, Weber K, Löffler B, Popp J, Deinhardt-Emmer S. Raman spectroscopic cellomics for the detection of SARS-CoV-2-associated neutrophil activation after TNF-α stimulation. Clin Transl Med. 2022 Dec;12(12):e1139. doi: 10.1002/ctm2.1139. PMID: 36536489; PMCID: PMC9763540.
Grebe T, Rudolf V, Gouleu CS, Löffler B, Adegnika AA, Shittu AO, Deinhardt-Emmer S, Niemann S, Schaumburg F. Neutralization of the Staphylococcus aureus Panton-Valentine leukocidin by African and Caucasian sera. BMC Microbiol. 2022 Sep 17;22(1):219. doi: 10.1186/s12866-022-02636-5. PMID: 36115948; PMCID: PMC9482280.
Garcia-Moreno M, Jordan PM, Günther K, Dau T, Fritzsch C, Vermes M, Schoppa A, Ignatius A, Wildemann B, Werz O, Löffler B, Tuchscherr L. Osteocytes Serve as a Reservoir for Intracellular Persisting Staphylococcus aureus Due to the Lack of Defense Mechanisms. Front Microbiol. 2022 Jul 22;13:937466. doi: 10.3389/fmicb.2022.937466. PMID: 35935196; PMCID: PMC9355688.
Jungwirth J, Häring C, König S, Giebeler L, Doshi H, Brandt C, Deinhardt-Emmer S, Löffler B, Ehrhardt C. D,L-Lysine-Acetylsalicylate + Glycine (LASAG) Reduces SARS-CoV-2 Replication and Shows an Additive Effect with Remdesivir. Int J Mol Sci. 2022 Jun 21;23(13):6880. doi: 10.3390/ijms23136880. PMID: 35805887; PMCID: PMC9266999.
Weis S, Hagel S, Palm J, Scherag A, Kolanos S, Bahrs C, Löffler B, Schmitz RPH, Rißner F, Brunkhorst FM, Pletz MW; SUPPORT Study Group. Effect of Automated Telephone Infectious Disease Consultations to Nonacademic Hospitals on 30-Day Mortality Among Patients With Staphylococcus aureus Bacteremia: The SUPPORT Cluster Randomized Clinical Trial. JAMA Netw Open. 2022 Jun 1;5(6):e2218515. doi: 10.1001/jamanetworkopen.2022.18515. PMID: 35749114; PMCID: PMC9233240.
Siwczak F, Cseresnyes Z, Hassan MIA, Aina KO, Carlstedt S, Sigmund A, Groger M, Surewaard BGJ, Werz O, Figge MT, Tuchscherr L, Loffler B, Mosig AS. Human macrophage polarization determines bacterial persistence of Staphylococcus aureus in a liver-on-chip-based infection model. Biomaterials. 2022 Jun 16;287:121632. doi: 10.1016/j.biomaterials.2022.121632. Epub ahead of print. PMID: 35728409.
Stallmach A, Grunert P, Stallhofer J, Löffler B, Baier M, Rödel J, Kiehntopf M, Neugebauer S, Pieper DH, Junca H, Tannapfel A, Merkel U, Schumacher U, Breternitz-Gruhne M, Heller T, Schauer A, Hartmann M, Steube A. Transfer of FRozen Encapsulated multi-donor Stool filtrate for active ulcerative Colitis (FRESCO): study protocol for a prospective, multicenter, double-blind, randomized, controlled trial. Trials. 2022 Feb 22;23(1):173. doi: 10.1186/s13063-022-06095-1. PMID: 35193638; PMCID: PMC8861997.
Miek L, Jordan PM, Günther K, Pace S, Beyer T, Kowalak D, Hoerr V, Löffler B, Tuchscherr L, Serhan CN, Gerstmeier J, Werz O. Staphylococcus aureus controls eicosanoid and specialized pro-resolving mediator production via lipoteichoic acid. Immunology. 2022 May;166(1):47-67. doi: 10.1111/imm.13449. Epub 2022 Mar 9. PMID: 35143048; PMCID: PMC9426618.
Bach K, Edel B, Höring S, Bartoničkova L, Glöckner S, Löffler B, Bahrs C, Rödel J. Performance of the eazyplex® BloodScreen GN as a simple and rapid molecular test for identification of Gram-negative bacteria from positive blood cultures. Eur J Clin Microbiol Infect Dis. 2022 Mar;41(3):489-494. doi: 10.1007/s10096-021-04383-3. Epub 2021 Nov 22. PMID: 34807364; PMCID: PMC8831353.
Bahrs C, Kimmig A, Weis S, Ankert J, Hagel S, Maschmann J, Stallmach A, Steiner A, Bauer M, Behringer W, Baier M, Kesselmeier M, Richert C, Zepf F, Walter M, Scherag A, Kiehntopf M, Löffler B, Pletz MW. Prospective surveillance study in a 1,400-bed university hospital: COVID-19 exposure at home was the main risk factor for SARS-CoV-2 point seroprevalence among hospital staff. Transbound Emerg Dis. 2022 Mar;69(2):720-730. doi: 10.1111/tbed.14041. Epub 2021 Mar 9. PMID: 33605549; PMCID: PMC8014017.
2021
Glöckner S, Hornung F, Baier M, Weis S, Pletz MW, Deinhardt-Emmer S, Löffler B, The CoNAN Study Group. Robust Neutralizing Antibody Levels Detected after Either SARS-CoV-2 Vaccination or One Year after Infection. Viruses. 2021 Oct 5;13(10):2003. doi: 10.3390/v13102003. PMID: 34696428; PMCID: PMC8537517.
Schöneweck F, Schmitz RPH, Rißner F, Scherag A, Löffler B, Pletz MW, Weis S, Brunkhorst FM, Hagel S. The epidemiology of bloodstream infections and antimicrobial susceptibility patterns in Thuringia, Germany: a five-year prospective, state-wide surveillance study (AlertsNet). Antimicrob Resist Infect Control. 2021 Sep 8;10(1):132. doi: 10.1186/s13756-021-00997-6. PMID: 34493334; PMCID: PMC8424790.
Michelson K, Löffler B, Höring S. Time to positivity as a prognostic factor in bloodstream infections with Enterococcus spp. Diagn Microbiol Infect Dis. 2021 Nov;101(3):115396. doi: 10.1016/j.diagmicrobio.2021.115396. Epub 2021 Apr 20. PMID: 34325178.
Deinhardt-Emmer S, Jäckel L, Häring C, Böttcher S, Wilden JJ, Glück B, Heller R, Schmidtke M, Koch M, Löffler B, Ludwig S, Ehrhardt C. Inhibition of Phosphatidylinositol 3-Kinase by Pictilisib Blocks Influenza Virus Propagation in Cells and in Lungs of Infected Mice. Biomolecules. 2021 May 29;11(6):808. doi: 10.3390/biom11060808. PMID: 34072389; PMCID: PMC8228449.
Löffler B, Tuchscherr L. Staphylococcus aureus Toxins: Promoter or Handicap during Infection? Toxins (Basel). 2021 Apr 19;13(4):287. doi: 10.3390/toxins13040287. PMID: 33921743; PMCID: PMC8072895.
Bühler S, Rödel J, Löffler B, Bauer M, Busch A. Draft Genome Sequence of Persistent Klebsiella grimontii AT013-Mero-001, Isolated from Human Feces. Microbiol Resour Announc. 2021 Apr 22;10(16):e00054-21. doi: 10.1128/MRA.00054-21. PMID: 33888494; PMCID: PMC8063637.
Kaluza M, Färber G, May B, Dobermann U, Pletz MW, Edel B, Löffler B, Doenst T. Heater-Cooler Devices and Risk of Contamination during Cardiac Surgery. Thorac Cardiovasc Surg. 2021 Dec;69(8):703-709. doi: 10.1055/s-0040-1721745. Epub 2021 Apr 21. PMID: 33882611.
Steiner A, Pletz M, Löffler B, Baier M. A novel SARS-CoV-2 IgG line-blot for evaluating discrepant IgG test results - Observations in pre-pandemic and follow-up samples of five patients. J Microbiol Immunol Infect. 2021 Oct;54(5):979-982. doi: 10.1016/j.jmii.2021.03.004. Epub 2021 Mar 31. PMID: 33849809; PMCID: PMC8011307.
Siegmund A, Afzal MA, Tetzlaff F, Keinhörster D, Gratani F, Paprotka K, Westermann M, Nietzsche S, Wolz C, Fraunholz M, Hübner CA, Löffler B, Tuchscherr L. Intracellular persistence of Staphylococcus aureus in endothelial cells is promoted by the absence of phenol-soluble modulins. Virulence. 2021 Dec;12(1):1186-1198. doi: 10.1080/21505594.2021.1910455. PMID: 33843450; PMCID: PMC8043190.
Egerer R, Edel B, Löffler B, Henke A, Rödel J. Performance of the RT-LAMP-based eazyplex® SARS-CoV-2 as a novel rapid diagnostic test. J Clin Virol. 2021 May;138:104817. doi: 10.1016/j.jcv.2021.104817. Epub 2021 Apr 1. PMID: 33836452; PMCID: PMC8015392.
Hornung F, Rogal J, Loskill P, Löffler B, Deinhardt-Emmer S. The Inflammatory Profile of Obesity and the Role on Pulmonary Bacterial and Viral Infections. Int J Mol Sci. 2021 Mar 26;22(7):3456. doi: 10.3390/ijms22073456. PMID: 33810619; PMCID: PMC8037155.
Deinhardt-Emmer S, Wittschieber D, Sanft J, Kleemann S, Elschner S, Haupt KF, Vau V, Häring C, Rödel J, Henke A, Ehrhardt C, Bauer M, Philipp M, Gaßler N, Nietzsche S, Löffler B, Mall G. Early postmortem mapping of SARS-CoV-2 RNA in patients with COVID-19 and the correlation with tissue damage. Elife. 2021 Mar 30;10:e60361. doi: 10.7554/eLife.60361. PMID: 33781385; PMCID: PMC8009677.
Kimmig A, Hagel S, Weis S, Bahrs C, Löffler B, Pletz MW. Management of Staphylococcus aureus Bloodstream Infections. Front Med (Lausanne). 2021 Mar 5;7:616524. doi: 10.3389/fmed.2020.616524. PMID: 33748151; PMCID: PMC7973019.
Deinhardt-Emmer S, Böttcher S, Häring C, Giebeler L, Henke A, Zell R, Jungwirth J, Jordan PM, Werz O, Hornung F, Brandt C, Marquet M, Mosig AS, Pletz MW, Schacke M, Rödel J, Heller R, Nietzsche S, Löffler B, Ehrhardt C. SARS-CoV-2 causes severe epithelial inflammation and barrier dysfunction. J Virol. 2021 Apr 26;95(10):e00110-21. doi: 10.1128/JVI.00110-21. Epub 2021 Feb 26. PMID: 33637603; PMCID: PMC8139673.
Reuken PA, Stallmach A, Pletz MW, Brandt C, Andreas N, Hahnfeld S, Löffler B, Baumgart S, Kamradt T, Bauer M. Severe clinical relapse in an immunocompromised host with persistent SARS-CoV-2 infection. Leukemia. 2021 Mar;35(3):920-923. doi: 10.1038/s41375-021-01175-8. Epub 2021 Feb 19. PMID: 33608636; PMCID: PMC7893131.
Teichgräber U, Malouhi A, Ingwersen M, Neumann R, Reljic M, Deinhardt-Emmer S, Löffler B, Behringer W, Lewejohann JC, Stallmach A, Reuken P. Ruling out COVID-19 by chest CT at emergency admission when prevalence is low: the prospective, observational SCOUT study. Respir Res. 2021 Jan 12;22(1):13. doi: 10.1186/s12931-020-01611-w. PMID: 33435973; PMCID: PMC7802980.
Tang D, Tao S, Chen Z, Koliesnik IO, Calmes PG, Hoerr V, Han B, Gebert N, Zörnig M, Löffler B, Morita Y, Rudolph KL. Correction: Dietary restriction improves repopulation but impairs lymphoid differentiation capacity of hematopoietic stem cells in early aging. J Exp Med. 2021 Jan 4;218(1):jem.2015110012042020C. doi: 10.1084/jem.2015110012042020C. Erratum for: J Exp Med. 2016 Apr 4;213(4):535-53. PMID: 33331868; PMCID: PMC7754676.
Weis S, Scherag A, Baier M, Kiehntopf M, Kamradt T, Kolanos S, Ankert J, Glöckner S, Makarewicz O, Hagel S, Bahrs C, Kimmig A, Proquitté H, Guerra J, Rimek D, Löffler B, Pletz MW; CoNAN Study Group. Antibody response using six different serological assays in a completely PCR-tested community after a coronavirus disease 2019 outbreak-the CoNAN study. Clin Microbiol Infect. 2021 Mar;27(3):470.e1-470.e9. doi: 10.1016/j.cmi.2020.11.009. Epub 2020 Nov 20. PMID: 33221432; PMCID: PMC7677041.
2020
Wilden JJ, Hrincius ER, Niemann S, Boergeling Y, Löffler B, Ludwig S, Ehrhardt C. Impact of Staphylococcus aureus Small Colony Variants on Human Lung Epithelial Cells with Subsequent Influenza Virus Infection. Microorganisms. 2020 Dec 15;8(12):1998. doi: 10.3390/microorganisms8121998. PMID: 33333815; PMCID: PMC7765246.
Reuken PA, Wüst M, Löffler B, Bauer M, Stallmach A. Letter: SARS-CoV-2-induced gastrointestinal inflammation. Aliment Pharmacol Ther. 2020 Dec;52(11-12):1748-1749. doi: 10.1111/apt.16087. PMID: 33205881; PMCID: PMC7753794.
Jordan PM, Gerstmeier J, Pace S, Bilancia R, Rao Z, Börner F, Miek L, Gutiérrez-Gutiérrez Ó, Arakandy V, Rossi A, Ialenti A, González-Estévez C, Löffler B, Tuchscherr L, Serhan CN, Werz O. Staphylococcus aureus-Derived α-Hemolysin Evokes Generation of Specialized Pro-resolving Mediators Promoting Inflammation Resolution. Cell Rep. 2020 Oct 13;33(2):108247. doi: 10.1016/j.celrep.2020.108247. PMID: 33053344; PMCID: PMC7729929.
Rödel J, Egerer R, Suleyman A, Sommer-Schmid B, Baier M, Henke A, Edel B, Löffler B. Use of the variplex™ SARS-CoV-2 RT-LAMP as a rapid molecular assay to complement RT-PCR for COVID-19 diagnosis. J Clin Virol. 2020 Nov;132:104616. doi: 10.1016/j.jcv.2020.104616. Epub 2020 Aug 31. PMID: 32891938; PMCID: PMC7457909.
Suligoy CM, Díaz RE, Gehrke AK, Ring N, Yebra G, Alves J, Gómez MI, Wendler S, Fitzgerald JR, Tuchscherr L, Löffler B, Sordelli DO, Llana MN, Buzzola FR. Acapsular Staphylococcus aureus with a non-functional agr regains capsule expression after passage through the bloodstream in a bacteremia mouse model. Sci Rep. 2020 Aug 24;10(1):14108. doi: 10.1038/s41598-020-70671-1. PMID: 32839485; PMCID: PMC7445255.
Tuchscherr L, Löffler B, Proctor RA. Persistence of Staphylococcus aureus: Multiple Metabolic Pathways Impact the Expression of Virulence Factors in Small-Colony Variants (SCVs). Front Microbiol. 2020 May 21;11:1028. doi: 10.3389/fmicb.2020.01028. PMID: 32508801; PMCID: PMC7253646.
Rödel J, Edel B, Braun SD, Ehricht R, Simon S, Fruth A, Löffler B. Simple differentiation of Salmonella Typhi, Paratyphi and Choleraesuis from Salmonella species using the eazyplex TyphiTyper LAMP assay. J Med Microbiol. 2020 Jun;69(6):817-823. doi: 10.1099/jmm.0.001201. Epub 2020 May 27. PMID: 32459614.
Schicke E, Cseresnyés Z, Rennert K, Vau V, Haupt KF, Hornung F, Nietzsche S, Swiczak F, Schmidtke M, Glück B, Koch M, Schacke M, Heller R, Mosig AS, Figge MT, Ehrhardt C, Löffler B, Deinhardt-Emmer S. Staphylococcus aureus Lung Infection Results in Down-Regulation of Surfactant Protein-A Mainly Caused by Pro-Inflammatory Macrophages. Microorganisms. 2020 Apr 16;8(4):577. doi: 10.3390/microorganisms8040577. PMID: 32316261; PMCID: PMC7232181.
Deinhardt-Emmer S, Rennert K, Schicke E, Cseresnyés Z, Windolph M, Nietzsche S, Heller R, Siwczak F, Haupt KF, Carlstedt S, Schacke M, Figge MT, Ehrhardt C, Löffler B, Mosig AS. Co-infection with Staphylococcus aureus after primary influenza virus infection leads to damage of the endothelium in a human alveolus-on-a-chip model. Biofabrication. 2020 Feb 19;12(2):025012. doi: 10.1088/1758-5090/ab7073. PMID: 31994489.
Leikeim RSM, Kesselmeier M, Löffler B, Rödel J, Höring S. Diagnostic accuracy and clinical impact of loop-mediated isothermal amplification for rapid detection of Staphylococcus aureus bacteremia: a retrospective observational study. Eur J Clin Microbiol Infect Dis. 2020 Apr;39(4):679-688. doi: 10.1007/s10096-019-03773-y. Epub 2019 Dec 10. PMID: 31823147.
Romp E, Arakandy V, Fischer J, Wolz C, Siegmund A, Löffler B, Tuchscherr L, Werz O, Garscha U. Exotoxins from Staphylococcus aureus activate 5-lipoxygenase and induce leukotriene biosynthesis. Cell Mol Life Sci. 2020 Oct;77(19):3841-3858. doi: 10.1007/s00018-019-03393-x. Epub 2019 Dec 5. PMID: 31807813.
Penzel A, Schützler K, Dröge J, Mellmann A, Ehricht R, Engelmann I, Braun SD, Schleenvoigt BT, Löffler B, Rödel J. Rapid culture-based identification of Shiga toxin-producing Escherichia coli and Shigella spp./Enteroinvasive E. coli using the eazyplex® EHEC complete assay. Eur J Clin Microbiol Infect Dis. 2020 Jan;39(1):151-158. doi: 10.1007/s10096-019-03704-x. Epub 2019 Sep 16. PMID: 31529306.
2019
Deinhardt-Emmer S, Haupt KF, Garcia-Moreno M, Geraci J, Forstner C, Pletz M, Ehrhardt C, Löffler B. Staphylococcus aureus Pneumonia: Preceding Influenza Infection Paves the Way for Low-Virulent Strains. Toxins (Basel). 2019 Dec 17;11(12):734. doi: 10.3390/toxins11120734. PMID: 31861176; PMCID: PMC6950557.
Zimmermann S, Klinger-Strobel M, Bohnert JA, Wendler S, Rödel J, Pletz MW, Löffler B, Tuchscherr L. Clinically Approved Drugs Inhibit the Staphylococcus aureus Multidrug NorA Efflux Pump and Reduce Biofilm Formation. Front Microbiol. 2019 Dec 3;10:2762. doi: 10.3389/fmicb.2019.02762. PMID: 31849901; PMCID: PMC6901667.
Reichardt E, Geraci J, Sachse S, Rödel J, Pfister W, Löffler B, Wagner Y, Eigenthaler M, Wolf M. Qualitative and quantitative changes in the oral bacterial flora occur shortly after implementation of fixed orthodontic appliances. Am J Orthod Dentofacial Orthop. 2019 Dec;156(6):735-744. doi: 10.1016/j.ajodo.2018.12.018. PMID: 31784007.
Gunaratnam G, Tuchscherr L, Elhawy MI, Bertram R, Eisenbeis J, Spengler C, Tschernig T, Löffler B, Somerville GA, Jacobs K, Herrmann M, Bischoff M. ClpC affects the intracellular survival capacity of Staphylococcus aureus in non-professional phagocytic cells. Sci Rep. 2019 Nov 7;9(1):16267. doi: 10.1038/s41598-019-52731-3. PMID: 31700127; PMCID: PMC6838064.
Kalinin DV, Agoglitta O, Van de Vyver H, Melesina J, Wagner S, Riemann B, Schäfers M, Sippl W, Löffler B, Holl R. Proline-based hydroxamates targeting the zinc-dependent deacetylase LpxC: Synthesis, antibacterial properties, and docking studies. Bioorg Med Chem. 2019 May 15;27(10):1997-2018. doi: 10.1016/j.bmc.2019.03.056. Epub 2019 Mar 30. PMID: 30954331.
Höring S, Sobotta K, Schneider S, Löffler B, Rödel J. Dwarfs in disguise: multiple spinal abscesses and spondylodiscitis caused by an Enterococcus faecium small-colony variant. Access Microbiol. 2019 Mar 27;1(1):e000012. doi: 10.1099/acmi.0.000012. PMID: 32974494; PMCID: PMC7470356.
Tuchscherr L, Pöllath C, Siegmund A, Deinhardt-Emmer S, Hoerr V, Svensson CM, Thilo Figge M, Monecke S, Löffler B. Clinical S. aureus Isolates Vary in Their Virulence to Promote Adaptation to the Host. Toxins (Basel). 2019 Mar 1;11(3):135. doi: 10.3390/toxins11030135. PMID: 30823631; PMCID: PMC6468552.
Wang J, Morita Y, Han B, Niemann S, Löffler B, Rudolph KL. Author Correction: Per2 induction limits lymphoid-biased haematopoietic stem cells and lymphopoiesis in the context of DNA damage and ageing. Nat Cell Biol. 2019 Jun;21(6):791-792. doi: 10.1038/s41556-019-0279-4. Erratum for: Nat Cell Biol. 2016 May;18(5):480-90. PMID: 30808996.
Rödel J, Mellmann A, Stein C, Alexi M, Kipp F, Edel B, Dawczynski K, Brandt C, Seidel L, Pfister W, Löffler B, Straube E. Use of MALDI-TOF mass spectrometry to detect nosocomial outbreaks of Serratia marcescens and Citrobacter freundii. Eur J Clin Microbiol Infect Dis. 2019 Mar;38(3):581-591. doi: 10.1007/s10096-018-03462-2. Epub 2019 Jan 24. PMID: 30680577.
Höring S, Massarani AS, Löffler B, Rödel J. Rapid antibiotic susceptibility testing in blood culture diagnostics performed by direct inoculation using the VITEK®-2 and BD Phoenix™ platforms. Eur J Clin Microbiol Infect Dis. 2019 Mar;38(3):471-478. doi: 10.1007/s10096-018-03445-3. Epub 2019 Jan 24. PMID: 30680555.
Schaumburg F, Witten A, Flamen A, Stoll M, Alabi AS, Kremsner PG, Löffler B, Zipfel PF, Velavan TP, Peters G. Complement 5a Receptor Polymorphisms Are Associated With Panton-Valentine Leukocidin-positive Staphylococcus aureus Colonization in African Pygmies. Clin Infect Dis. 2019 Feb 15;68(5):854-856. doi: 10.1093/cid/ciy666. PMID: 30192927.
2018
Bauer M, Coldewey SM, Leitner M, Löffler B, Weis S, Wetzker R. Deterioration of Organ Function As a Hallmark in Sepsis: The Cellular Perspective. Front Immunol. 2018 Jun 26;9:1460. doi: 10.3389/fimmu.2018.01460. PMID: 29997622; PMCID: PMC6028602.
Tuchscherr L, Korpos È, van de Vyver H, Findeisen C, Kherkheulidze S, Siegmund A, Deinhardt-Emmer S, Bach O, Rindert M, Mellmann A, Sunderkötter C, Peters G, Sorokin L, Löffler B. Staphylococcus aureus requires less virulence to establish an infection in diabetic hosts. Int J Med Microbiol. 2018 Oct;308(7):761-769. doi: 10.1016/j.ijmm.2018.05.004. Epub 2018 May 22. PMID: 29843979.
Geraci J, Neubauer S, Pöllath C, Hansen U, Rizzo F, Krafft C, Westermann M, Hussain M, Peters G, Pletz MW, Löffler B, Makarewicz O, Tuchscherr L. Author Correction: The Staphylococcus aureus extracellular matrix protein (Emp) has a fibrous structure and binds to different extracellular matrices. Sci Rep. 2018 May 25;8(1):8396. doi: 10.1038/s41598-018-26315-6. Erratum for: Sci Rep. 2017 Oct 20;7(1):13665. PMID: 29802334; PMCID: PMC5970134.
Karrasch M, Geraci J, Sachse S, Rödel J, Löffler B, Bauer M, Thomas-Rüddel D, Hagel S, Aschenbach R, Bloos F. Early adjustment of antimicrobial therapy after PCR/electrospray ionization mass spectrometry-based pathogen detection in critically ill patients with suspected sepsis. Clin Chem Lab Med. 2018 Jul 26;56(8):e207-e209. doi: 10.1515/cclm-2017-1110. PMID: 29626413.
van Krüchten A, Wilden JJ, Niemann S, Peters G, Löffler B, Ludwig S, Ehrhardt C. Staphylococcus aureus triggers a shift from influenza virus-induced apoptosis to necrotic cell death. FASEB J. 2018 May;32(5):2779-2793. doi: 10.1096/fj.201701006R. Epub 2018 Jan 11. PMID: 29401589.
Mödinger Y, Löffler B, Huber-Lang M, Ignatius A. Complement involvement in bone homeostasis and bone disorders. Semin Immunol. 2018 Jun;37:53-65. doi: 10.1016/j.smim.2018.01.001. Epub 2018 Feb 1. PMID: 29395681.
Niemann S, Bertling A, Brodde MF, Fender AC, Van de Vyver H, Hussain M, Holzinger D, Reinhardt D, Peters G, Heilmann C, Löffler B, Kehrel BE. Panton-Valentine Leukocidin associated with S. aureus osteomyelitis activates platelets via neutrophil secretion products. Sci Rep. 2018 Feb 1;8(1):2185. doi: 10.1038/s41598-018-20582-z. PMID: 29391581; PMCID: PMC5794969.
Deinhardt-Emmer S, Höring S, Mura C, Hillemann D, Hermann B, Sachse S, Bohnert J, Löffler B. First Time Isolation of Mycobacterium hassiacum From a Respiratory Sample. Clin Med Insights Circ Respir Pulm Med. 2018 Jan 3;12:1179548417747529. doi: 10.1177/1179548417747529. PMID: 29326536; PMCID: PMC5757423.
2017
Saupe A, Edel B, Pfister W, Löffler B, Ehricht R, Rödel J. Acute diarrhoea due to a Shiga toxin 2e-producing Escherichia coli O8 : H19. JMM Case Rep. 2017 Jun 14;4(6):e005099. doi: 10.1099/jmmcr.0.005099. PMID: 29026626; PMCID: PMC5630968.
Zimmermann S, Tuchscherr L, Rödel J, Löffler B, Bohnert JA. Optimized efflux assay for the NorA multidrug efflux pump in Staphylococcus aureus. J Microbiol Methods. 2017 Nov;142:39-40. doi: 10.1016/j.mimet.2017.09.001. Epub 2017 Sep 5. PMID: 28887002.
Tuchscherr L, Geraci J, Löffler B. Staphylococcus aureus Regulator Sigma B is Important to Develop Chronic Infections in Hematogenous Murine Osteomyelitis Model. Pathogens. 2017 Jul 15;6(3):31. doi: 10.3390/pathogens6030031. PMID: 28714889; PMCID: PMC5617988.
Kentrup D, Bovenkamp P, Busch A, Schuette-Nuetgen K, Pawelski H, Pavenstädt H, Schlatter E, Herrmann KH, Reichenbach JR, Löffler B, Heitplatz B, Van Marck V, Yadav NN, Liu G, van Zijl PCM, Reuter S, Hoerr V. GlucoCEST magnetic resonance imaging in vivo may be diagnostic of acute renal allograft rejection. Kidney Int. 2017 Sep;92(3):757-764. doi: 10.1016/j.kint.2017.04.015. Epub 2017 Jul 12. PMID: 28709641.
Deinhardt-Emmer S, Hoerr V, Löffler B. Vascular graft infection: a new model for treatment management? Future Microbiol. 2017 Jun;12:651-654. doi: 10.2217/fmb-2017-0068. Epub 2017 May 25. PMID: 28541093.
Klemm C, Bruchhagen C, van Krüchten A, Niemann S, Löffler B, Peters G, Ludwig S, Ehrhardt C. Mitogen-activated protein kinases (MAPKs) regulate IL-6 over-production during concomitant influenza virus and Staphylococcus aureus infection. Sci Rep. 2017 Feb 14;7:42473. doi: 10.1038/srep42473. PMID: 28195157; PMCID: PMC5307969.
Reuken PA, Torres D, Baier M, Löffler B, Lübbert C, Lippmann N, Stallmach A, Bruns T. Correction: Risk Factors for Multi-Drug Resistant Pathogens and Failure of Empiric First-Line Therapy in Acute Cholangitis. PLoS One. 2017 Feb 13;12(2):e0172373. doi: 10.1371/journal.pone.0172373. Erratum for: PLoS One. 2017 Jan 11;12 (1):e0169900. PMID: 28192501; PMCID: PMC5305072.
Van de Vyver H, Bovenkamp PR, Hoerr V, Schwegmann K, Tuchscherr L, Niemann S, Kursawe L, Grosse C, Moter A, Hansen U, Neugebauer U, Kuhlmann MT, Peters G, Hermann S, Löffler B. A Novel Mouse Model of Staphylococcus aureus Vascular Graft Infection: Noninvasive Imaging of Biofilm Development in Vivo. Am J Pathol. 2017 Feb;187(2):268-279. doi: 10.1016/j.ajpath.2016.10.005. Epub 2017 Jan 11. PMID: 28088288.
Reuken PA, Torres D, Baier M, Löffler B, Lübbert C, Lippmann N, Stallmach A, Bruns T. Risk Factors for Multi-Drug Resistant Pathogens and Failure of Empiric First-Line Therapy in Acute Cholangitis. PLoS One. 2017 Jan 11;12(1):e0169900. doi: 10.1371/journal.pone.0169900. Erratum in: PLoS One. 2017 Feb 13;12 (2):e0172373. PMID: 28076388; PMCID: PMC5226732.
Idelevich EA, Kreis C, Löffler B, Peters G. Staphylococcus aureus-Associated Musculoskeletal Infections. Curr Top Microbiol Immunol. 2017;409:229-261. doi: 10.1007/82_2016_19. PMID: 27380269.
2016
Hagel S, Ludewig K, Moeser A, Baier M, Löffler B, Schleenvoigt B, Forstner C, Pletz MW. Characteristics and management of patients with influenza in a German hospital during the 2014/2015 influenza season. Infection. 2016 Oct;44(5):667-72. doi: 10.1007/s15010-016-0920-0. Epub 2016 Jul 5. PMID: 27380386.
Galstyan A, Block D, Niemann S, Grüner MC, Abbruzzetti S, Oneto M, Daniliuc CG, Hermann S, Viappiani C, Schäfers M, Löffler B, Strassert CA, Faust A. Corrigendum: Labeling and Selective Inactivation of Gram-Positive Bacteria Employing Bimodal Photoprobes with Dual Readouts. Chemistry. 2016 Jun 27;22(27):9051. doi: 10.1002/chem.201601576. Epub 2016 Jun 1. Erratum for: Chemistry. 2016 Apr 4;22(15):5243-52. PMID: 27334237.
Weis S, Kaasch AJ, Rieg S, Löffler B, Hagel S, Forstner C, Brunkhorst FM, Pletz MW. Behandlung bei Penicillin-sensiblem S. aureus - Erwiderung [Treatment of penicillin-sensitive staphylococcus aureus - in reply]. Dtsch Med Wochenschr. 2016 May;141(10):675. German. doi: 10.1055/s-0041-108937. Epub 2016 May 13. PMID: 27176056.
Weis S, Kaasch AJ, Rieg S, Löffler B, Hagel S, Forstner C, Brunkhorst FM, Pletz MW. Wann welches Antibiotikum einsetzen? - Erwiderung [Which antibiotic to choose? - in reply]. Dtsch Med Wochenschr. 2016 May;141(10):675-6. German. doi: 10.1055/s-0041-108934. Epub 2016 May 13. PMID: 27176055.
Hoerr V, Duggan GE, Zbytnuik L, Poon KK, Große C, Neugebauer U, Methling K, Löffler B, Vogel HJ. Characterization and prediction of the mechanism of action of antibiotics through NMR metabolomics. BMC Microbiol. 2016 May 10;16:82. doi: 10.1186/s12866-016-0696-5. PMID: 27159970; PMCID: PMC4862084.
Wang J, Morita Y, Han B, Niemann S, Löffler B, Rudolph KL. Per2 induction limits lymphoid-biased haematopoietic stem cells and lymphopoiesis in the context of DNA damage and ageing. Nat Cell Biol. 2016 May;18(5):480-90. doi: 10.1038/ncb3342. Epub 2016 Apr 18. Erratum in: Nat Cell Biol. 2019 Jun;21(6):791-792. PMID: 27088856.
Kahl BC, Becker K, Löffler B. Clinical Significance and Pathogenesis of Staphylococcal Small Colony Variants in Persistent Infections. Clin Microbiol Rev. 2016 Apr;29(2):401-27. doi: 10.1128/CMR.00069-15. PMID: 26960941; PMCID: PMC4786882.
Tang D, Tao S, Chen Z, Koliesnik IO, Calmes PG, Hoerr V, Han B, Gebert N, Zörnig M, Löffler B, Morita Y, Rudolph KL. Dietary restriction improves repopulation but impairs lymphoid differentiation capacity of hematopoietic stem cells in early aging. J Exp Med. 2016 Apr 4;213(4):535-53. doi: 10.1084/jem.20151100. Epub 2016 Mar 7. Erratum in: J Exp Med. 2021 Jan 4;218(1): PMID: 26951333; PMCID: PMC4821645.
Galstyan A, Block D, Niemann S, Grüner MC, Abbruzzetti S, Oneto M, Daniliuc CG, Hermann S, Viappiani C, Schäfers M, Löffler B, Strassert CA, Faust A. Labeling and Selective Inactivation of Gram-Positive Bacteria Employing Bimodal Photoprobes with Dual Readouts. Chemistry. 2016 Apr 4;22(15):5243-52. doi: 10.1002/chem.201504935. Epub 2016 Mar 1. Erratum in: Chemistry. 2016 Jun 27;22(27):9051. PMID: 26929124.
Rödel J, Karrasch M, Edel B, Stoll S, Bohnert J, Löffler B, Saupe A, Pfister W. Antibiotic treatment algorithm development based on a microarray nucleic acid assay for rapid bacterial identification and resistance determination from positive blood cultures. Diagn Microbiol Infect Dis. 2016 Mar;84(3):252-7. doi: 10.1016/j.diagmicrobio.2015.10.021. Epub 2015 Nov 14. PMID: 26712265.
Elschner T, Lüdecke C, Kalden D, Roth M, Löffler B, Jandt KD, Heinze T. Zwitterionic Cellulose Carbamate with Regioselective Substitution Pattern: A Coating Material Possessing Antimicrobial Activity. Macromol Biosci. 2016 Apr;16(4):522-34. doi: 10.1002/mabi.201500349. Epub 2015 Dec 3. PMID: 26632022.
Tuchscherr L, Löffler B. Staphylococcus aureus dynamically adapts global regulators and virulence factor expression in the course from acute to chronic infection. Curr Genet. 2016 Feb;62(1):15-7. doi: 10.1007/s00294-015-0503-0. Epub 2015 Jun 30. PMID: 26123224.
2015
Grüner M, Tuchscherr L, Löffler B, Gonnissen D, Riehemann K, Staniford MC, Kynast U, Strassert CA. Selective Inactivation of Resistant Gram-Positive Pathogens with a Light-Driven Hybrid Nanomaterial. ACS Appl Mater Interfaces. 2015 Sep 23;7(37):20965-71. doi: 10.1021/acsami.5b06742. Epub 2015 Sep 11. PMID: 26360157.
Weis S, Kaasch AJ, Rieg S, Löffler B, Hagel S, Forstner C, Brunkhorst FM, Pletz MW. Staphylococcus-aureus-Bakteriämie - eine eigene Entität [Staphylococcus aureus bacteremia - a distinct entity]. Dtsch Med Wochenschr. 2015 Jun;140(13):982-9. German. doi: 10.1055/s-0041-102453. Epub 2015 Jun 26. PMID: 26115133.
Tuchscherr L, Bischoff M, Lattar SM, Noto Llana M, Pförtner H, Niemann S, Geraci J, Van de Vyver H, Fraunholz MJ, Cheung AL, Herrmann M, Völker U, Sordelli DO, Peters G, Löffler B. Sigma Factor SigB Is Crucial to Mediate Staphylococcus aureus Adaptation during Chronic Infections. PLoS Pathog. 2015 Apr 29;11(4):e1004870. doi: 10.1371/journal.ppat.1004870. PMID: 25923704; PMCID: PMC4414502.
Warnking K, Klemm C, Löffler B, Niemann S, van Krüchten A, Peters G, Ludwig S, Ehrhardt C. Super-infection with Staphylococcus aureus inhibits influenza virus-induced type I IFN signalling through impaired STAT1-STAT2 dimerization. Cell Microbiol. 2015 Mar;17(3):303-17. doi: 10.1111/cmi.12375. Epub 2014 Nov 19. PMID: 25293394.
2014
Szafranska AK, Oxley AP, Chaves-Moreno D, Horst SA, Roßlenbroich S, Peters G, Goldmann O, Rohde M, Sinha B, Pieper DH, Löffler B, Jauregui R, Wos-Oxley ML, Medina E. High-resolution transcriptomic analysis of the adaptive response of Staphylococcus aureus during acute and chronic phases of osteomyelitis. mBio. 2014 Dec 23;5(6):e01775-14. doi: 10.1128/mBio.01775-14. PMID: 25538190; PMCID: PMC4278534.