CV
| 1994 | University-entrance diploma in Neubrandenburg |
| 1994-1999 | Biology studies at the Friedrich-Schiller University Jena |
| 1998-1999 | Diploma thesis at the Clinics of Neurology of the University Hospital Jena |
| 1999-2004 | PhD student at the Institute of Physiology II of the University Hospital Jena |
| 2003 | Dissertation |
| since 2004 | Research associate at the Institute of Physiology II of the University Hospital Jena |
Research
- Ligand binding and activation gating in HCN pacemaker channels
- Structure-function relation in CNG channels
- Ligand binding and activation gating in nicotinic acetylcholine receptors
Skills
- Patch-clamp and voltage-clamp technique
- Confocal Patch-Clamp Fluorometry (confocal PCF)
- Live-cell imaging / immunocytochemistry
Collaborations
- Dominik Wiemuth, Axel Schmidt, Stefan Gründer, Uniklinik RWTH Aachen, Institut für Physiologie
- Chris Ulens, KU Leuven, Laboratory of Structural Neurobiology
- Andrew Plested, Leibnitz Institute for Molecular Pharmacology Berlin, research group for Molecular Neuroscience and Biophysics
- Lucia Sivilotti, University College London, Department of Neuroscience, Physiology & Pharmacology
Publications
Kesters, D., Brams, M., Nys, M., Wijckmans, E., Spurny, R., Voets, T., Tytgat, J., Kusch, J., and Ulens, C. (2015)
PloS one 10, e0116369
Schmidt, A., Lenzig, P., Oslender-Bujotzek, A., Kusch, J., Dias Lucas, S., and Gründer, S. (2014)
PLoS one 9, e111549
Brams, M., Kusch, J., Spurny, R., Benndorf, K., and Ulens, C. (2014)
Proc. Natl. Acad. Sci. USA 111, 7855-7860
Kusch, J., and Zifarelli, G. (2014)
Biophys. J. 18, 1250-7
Nache, V., Zimmer, T., Wongsamitkul, N., Schmauder, R., Kusch, J., Reinhardt, L., Bonigk, W., Seifert, R., Biskup, C., Schwede, F., and Benndorf, K. (2012)
Sci. Signal. 5, ra48
Kusch, J., Thon, S., Schulz, E., Biskup, C., Nache, V., Zimmer, T., Seifert, R., Schwede, F., and Benndorf, K. (2012)
Nat. Chem. Biol. 8, 162-169
Kusch, J., Biskup, C., Thon, S., Schulz, E., Nache, V., Zimmer, T., Schwede, F., and Benndorf, K. (2010)
Neuron 67, 75-85
Kusch, J., Zimmer, T., Holschuh, J., Biskup, C., Schulz, E., Nache, V., and Benndorf, K. (2010)
Biophys. J. 99, 2488-96
Biskup, C., Kusch, J., Schulz, E., Nache, V., Schwede, F., Lehmann, F., Hagen, V., and Benndorf, K. (2007)
Nature 446, 440-443
Kusch, J., Nache, V., and Benndorf, K. (2004)
J. Physiol. 560, 605-16
Funding and Awards
- Project P2 "Scrutinizing the function of the cyclic-nucleotide binding domain in the activation of HCN channels" of the Research Unit 2518 DynIon funded by the DFG (2017)
- Project B7 "Relating ligand binding and activation gating in nicotinic acetylcholine receptors" of the SFB/TRR 166 ReceptorLight funded by the DFG (2015)
- Poster Award at the Meeting of the German Physiological Society 2013
- DFG grant "Relating ligand binding and activation gating in nicotinic acetylcholine receptors" (2013-2015)
- Travel grant of the GlaxoSmithKline-Stiftung
- Project „ProChance 2008 - Förderung der Chancengleichheit der Frau in der Wissenschaft“
- Award for best exam 2000 at the Biological-Pharmaceutical Faculty of the Friedrich-Schiller University Jena
- First Poster Award at the 33rd Meeting of the EWGCCE 2009 in Cologne
Teaching
- Lecture "ECG, kidney physiology, acid-base metabolism, electrolyte metabolism"
- Seminar „Physiology for human medicine“
- Seminar „Clinical Physiology: Diving and Climbing“
- Seminar "Clinical Physiology: ECG"
- Practical courses „Physiology for human medicine, dentistry und pharmacy“
- Practical course "Ion channels: Physiology, Pathophysiology and Pharmacology"
- Supervising of the diploma project „Interaction of intracellular regions during the gating process of cyclic-nucleotide gated channels” (2009)
- Supervising of the diploma project "cAMP- and voltage dependent gating of heterotetrameric HCN2/HCN4 pacemaker channels” (2011-2012)
- SciCoach in the Opsis program of the University Jena (Optimization of Professional Support for International Students)