In dieser monatlichen Seminarreihe werden unsere Forschenden zusammen mit KollegInnen einen spannenden Einblick in ihre laufenden Projekte und Lieblingsthemen geben.
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Natürlich sind alle MitarbeiterInnen, Studierenden und andere Interessenten herzlich willkommen!
nächster Vortrag:
Do., 13.06.2024
16:00 - 18:00 Uhr
Prof. Dr. Veronika Engert, Prof. Dr. Nicolas Rohleder
Ort: Hörsaal der Klinik für Psychiatrie und Psychotherapie, Philosophenweg 3, 07743 Jena
Title: Stress Pathways to Disease: Traditional and Digital Biomarkers of Stress
Abstract:
Psychosocial stress is an important precursor of disease and reduced quality of life in humans. The biological pathways between stress exposure and pathophysiological processes underlying disease have received substantial attention, primarily focusing on the role of the hypothalamus pituitary adrenal (HPA) axis and sympathetic nervous system (SNS). How activation of these stress systems translates into physiological disease, however, remains insufficiently understood. Recent research has therefore focused on systemic inflammation as a pathway, because (a) stress systems are known to control the inflammatory system, (b) elevated inflammatory system activity often accompanies chronic psychosocial distress, and (c) inflammation plays a key role in the pathophysiology of diseases such as cardiovascular disease, type2 diabetes, and cancer. As quantification of these biological processes is often invasive, expensive, and labor-intensive, we are currently increasing our efforts aimed at permitting more non-invasive, non-intervening, noninterfering biobehavioral research. Data will be presented addressing different aspects of stress system control of inflammatory mechanisms in the context of chronic and acute psychosocial stress, followed by initial results of our aim to reduce invasiveness of our research, including digital biomarkers of stress.