Publikationen

1992-1995

Berndt A., Kosmehl H., Voigt A., Zintl F.
Zelluläre Differenzierung, Rezeptorstatus und Formierung der extrazellulären Matrix in neuroektodermalen Tumoren des Kindesalters (Primärtumor, Zellkultur, Xenotransplantat) erste Ergebnisse.
Wissenschaftliche Beiträge Festsymposium (Zintl F., ed.) Druckhaus Mayer Verlag Erlangen 1992
Berndt A., Kosmehl H., Katenkamp D., Tauchmann V.
The Appearance of the myofibroblastic phenotype in Dupuytren´s disease is associated with a fibronectin, laminin, collagen type IV and tenascin extracellular matrix.
Pathobiology 1994,62(2):55-58
Berndt A., Kosmehl H., Mandel U., Gabler U., Luo X., Celeda D., Zardi L., Katenkamp D.
TGFß and bFGF synthesis and localization in nodular palmar fibromatosis (Morbus Dupuytren) relative to cellular activity, myofibroblast phenotype and oncofetal variants of fibronectin.
Histochemical J. 1995,27:1014-1020
Kosmehl H., Berndt A., Katenkamp D., Hyckel P., Stiller K.-J., Gabler U., Langbein L., Reh T.
Integrin receptors and their relationship to cellular proliferation and differentiation of oral squamous cell carcinoma. A quantitative immunhistochemical study.
Oral Pathol. Med. 1995, 24(8):343-348
Kosmehl H., Berndt A., Katenkamp D., Mandel U., Bohle R., Gabler U., Celeda D.
Differential expression of fibronectin splice variants, oncofetal glycosylated fibronectin and laminin isoforms in nodular palmarfibromatosis.
Path. Res. Pract. 1995, 191:1105-1113
Celeda D., Mühlig P., Berndt A., Kosmehl H., Löber G., Greulich K. O.
Cell specific differences on isolated nuclei of two cell types regarding transcription as well as hybridization pattern of a specific gene.
Cell Mol. Biol. 1995, 41(8):1025-1032
Hyckel P., Kosmehl H., Berndt A., Hesse J., Stiller K.-J., Robotta C. Immunhistochemische Demonstration von CD 44 H, CD 44 v3 und CD 44 v6 im oralen Plattenepithelkarzinom. Quantifizierung und Korrelation zum morphologischen Malignitätsgrad sowie zum TNM-Status.
Dtsch. Z. Mund Kiefer GesichtsChir. 1995,19(6):284-289
Kosmehl H., Langbein L., Katenkamp D., Vogel W., Berndt A.
Laminin matrix formation and S-100 protein and/or desmin-positive cells in malignant fibrous histiocytoma (MFH).
Histol. Histopath. 1993; 8:425-428

1996-2000

Berndt A., Kosmehl H., Celeda D., Katenkamp D.
Reduced formamide content and hybridization temperature results in increased non-radioactive mRNA in situ hybridization signals.
Acta Histochem. 1996,98:79-87
Berndt A., Hyckel P., Könneker A., Katenkamp D., Kosmehl H.
Oral squamous cell carcinoma is associated with a laminin-5 matrix re-organization but independent of basement membrane and hemidesmosome formation. Clues from an in vitro invasion model.
Invas. Metast. 1997, 17:251-258
Berndt A., Kosmehl H., Borsi L., Luo XM., Zardi L. Katenkamp D.
Evidence of ED-B+ fibronectin synthesis in human tissues by non radioactive RNA in situ hybridization. Investigations on carcinoma (oral squamous cell and breast carcinoma), chronic inflammation (rheumatoid synovitis) and fibromatosis (Morbus Dupuytren).
Histochem. Cell Biol. 1998, 109:249-255
Berndt A., Hyckel P., Könneker A., Kosmehl H.
Dreidimensionales In-vitro-Invasionsmodell für orale Plattenepithelkarzinome.
Mund Kiefer GesichtsChir. 1998;2:256-260
Berndt A., Luo X., Böhmer F.-D., Kosmehl H.
Expression of the transmembrane proteine tyrosine phosphatase RPTPa in human oral squamous cell carcinoma.
Histochem. Cell Biol. 1999, 111:399-403
Berndt A., Johannesson J, Haas M., Arkona C., Katenkamp D., Wiederanders B., Hyckel P., Kosmehl H.
Simultaneous enzyme overlay membranes (EOM´s) based in situ zymography and immunofluorescence technique reveals cathepsin B-like activity in a subset of tumour vessels.
Histochem. Cell Biol. 2000, 114(1):63-68
Berndt A., Borsi L., Hyckel P., Kosmehl H.
Fibrillar co-deposition of laminin-5 and large unspliced tenascin-C in invasive front of oral squamous cell carcinoma in vivo and in vitro.
Cancer. Res. Clinical Oncol. 2001, 127:286-292
Kosmehl H., Berndt A., Katenkamp D.
Molecular variants of fibronectin and Laminin. Structure, physiological occurrence and pathohistological aspects.
Virch. Arch. 1996, 429:311-322
Kosmehl H., Berndt A., Straßburger S., Hyckel P., Katenkamp D.
Modulation of the laminin (lam) chain deposition in basement membrane region and the deposition of fibronectin (fn) variants in the stroma of normal, hyperplastic and malignant oral epithelium.
Pathol. Int. 1996;46,Suppl.1
Gabler U., Berndt A., Kosmehl H., Mandel U., Zardi L., Müller S., Stelzner A., Katenkamp D.
Matrix remodelling in dilated cardiomyopathy includs the occurrence of oncofetal fibronectin molecular variants.
British Heart Journal 1996,75:358-362
Hindermann W., Berndt A., Wunderlich H., Katenkamp D., Kosmehl H.
Quantitative evaluation of apoptosis and proliferation in renal cell carcinoma. Correlation to tumor subtype, cytological grade according Thoenes-classification and the occurrence of metastasis.
Path. Res. Pract. 1997, 193:1-7
Voigt A., Berndt A., Lauterbach H., Carlson C., Hüller M., Stiller K.-J., Gottschild D., Zintl F.
Radioimmunodetection of neuroblastoma cells with I-131-radiolabelled antibodies.
Cancer Biotherapy & Radiopharmaceuticals 1997, 12(3):187-194
Wilutzky B., Berndt A., Katenkamp D., Kosmehl H.
Programmed cell death in nodular palmar fibromatosis (Morbus Dupuytren).
Histol. Histopathol. 1998;13:67-72
Strassburger S., Berndt A., Hyckel P., Katenkamp D., Kosmehl H.
Differential expression of laminin chains in the human major salivary gland.
Histochem. J. 1998, 30:81-89
Junghänel A., Berndt A., Kosmehl H., Hyckel P.
Zellkinetik oraler Plattenepithelkarzinome.
Mund Kiefer GesichtsChir. 1998, 2:250-255
Löffler U., Berndt A., Kosmehl H., Beintker M., Werner W., Schubert J.
Ein ungewöhnlicher Fall von Genitaltuberkulose: Ein Fallbericht.
Der Urologe A 1999, 38(1):60-64
Henning K., Berndt A., Katenkamp D., Kosmehl H.
Loss of laminin-5 in the epithelium stroma interface. An immunohistochemical marker of malignancy in epithelial tumourous lesions of the breast.
Histopathol. 1999, 34:305-309
Hindermann H., Berndt A., Borsi L., Luo X., Hyckel P., Katenkamp D., Kosmehl H.
Synthesis and protein distribution of the unspliced large tenascin-C isoform in oral squamous cell carcinoma.
J. Pathol. 1999, 189:475-480
Kosmehl H., Berndt A., Strassburger S., Borsi L., Rousselle P., Mandel U., Hyckel P., Zardi L., Katenkamp D.
Distribution of laminin and fibronectin isoforms in oral mucosa and oral squamous cell carcinoma.
Brit. J. Cancer 1999, 81(6):1071-1079
Haas M., Berndt A., Hyckel P., Stiller KJ., Kosmehl H.
Laminin-5 bei Erkrankungen der Mundhöhle.
Dtsch. Z. Mund Kiefer GesichtsChir. 2000, 4:25-29
Luo X., Celler J.W., Berndt A.
LacSwitchTM inducible mammalian expression system in mouse Swiss 3T3 fibroblasts.
Molecular and Cellular Biochemistry 1999, 200(1-2):127-132
Ebhardt H., Eidner T., Berndt A., Katenkamp D., Kosmehl H.
Das POEMS Syndrom - Ein Fallbericht.
Pathologe 2000, 21:255-259
Häkkinen L., Hildebrand H.C., Berndt A., Kosmehl H., Larjava H.
Immunolocalization of tenascin-C, a 9 integrin subunit, and a vb 6 integrin during wound healing in human oral mucosa.
J Histochem Cytochem 2000, 48:985-998
Straßburger S., Hyckel P., Schumann D., Berndt A., Kosmehl H.
Basaloides Plattenepithelkarzinom (basaloid-squamöses Karzinom) des Mundbodens. Fallbericht, Differentialdiagnose und Beeinflußbarkeit durch neoadjuvante Chemotherapie.
Mund Kiefer GesichtsChir 1997; 1:239-243
Herbst C., Kosmehl H., Stiller K.-J., Berndt A., Eiselt M., Schubert J., Katenkamp D.
Evaluation of microvessel density by computerised image analysis in human renal cell carcinoma. Correlation to tumor size, nuclear grade, proliferative activity and occurrence of metastasis.
Journal of Cancer Research and Clinical Oncology 1998; 124:141-147
Vogel W., Kanz L., Brugger W., Berndt A., Kosmehl H.
Expression of laminin ß2 chain in normal human bone marrow.
Blood 1999; 94:1143-1145

2001

Hyckel P., Berndt A., Wutzler P., Kosmehl H.
Tumoren des Gesichtes bei organtransplantierten Patienten.
Dtsch. Z. Mund Kiefer GesichtsChir. 2001, 5:94-97
Schleier P., Berndt A., Berndt A., Dahse R., Zenk W., Hyckel P., Kosmehl H.
Experimentelle 5-Aminolävulinsäure - induzierte Photodynamische Therapie (ALA-PDT) oraler Karzinome: Ein Verfahren zur Therapie solider Tumoren und Aufklärung des Zelltodes.
Dtsch. Z. Mund Kiefer GesichtsChir. 2001, 5:98-104
Haas KM., Berndt A., Stiller K.J., Hyckel P., Kosmehl H.
Quantitative analysis of laminin-5 in basement membrane of normal, hyperlastic oral mucosa and oral squamous cell carcinoma by confocal immunofluorescence imaging.
J. Histochem. Cytochem. 2001, 49(10):1261-1268
Reissig D., Clement J., Sänger J., Berndt A., Kosmehl H., Böhmer FD.
Elevated activity and expression of Src-family kinases in human breast carcinoma tissue versus matched non-tumor tissue.
J. Cancer Res. Clin. Oncol. 2001; 127:226-230
Wunderlich H., Reichelt O., Zermann DH., Schubert J., Berndt A., Kosmehl H.
Fetal fibronectin: A new screening-marker for bladder cancer?
Oncology Reports 2001; 8:669-672
Keilhack H., Müller M., Böhmer S.-A., Frank C., Weidner K. M., Birchmeier W., Ligensa T., Berndt A., Kosmehl H., Günther B., Müller T., Birchmeier C., Böhmer F. D.
Negative regulation of Ros receptor tyrosine kinase signaling: An epithelial function of the SH2 domain protein tyrosine phosphatase SHP-1.
J Cell Biol 2001; 152:325-334

2002

Dahse R., Berndt A., Kosmehl H.
Total-RNA-based target design for microarray analysis of defined tumor areas.
Biotechniques 2002, 32(4):744-748
Dahse R., Berndt A., Haas KM., Hyckel P., Böhmer F. D., Claussen U., Kosmehl H.
Coculture-LCM: Laser capture microdissection in 2-D coculture models as a novel tool to study tumor-stroma-interactions.
Biotechniques 2002, 33(3):476-480
Kosmehl H., Berndt A., Haas KM., Hyckel P.
Laminin-5. A potential tool in diagnosis of head neck squamons cell carcinoma.
Journal of Slovene Medical Association (ZDRAV VESTN) 2002, 71:III-45 - III-47
Halin C., Rondini S., Nilsson F., Berndt A., Kosmehl H., Zardi L., Neri D.
Enhancement of the anti-tumor activity of interleukin 12 by targeted delivery to neo-vasculature.
Nature Biotech. 2002;20(3):264-269
Carnemolla B., Borsi L., Balza E., Castellani P., Meazza R., Berndt A., Ferrini S., Kosmehl H., Neri D., Zardi L.
Enhancement of the anti-tumor properties of interleukin-2 by its targeted delivery to the tumor blood vessel extracellular matrix.
Blood 2002; 99(5):1659-1665

2003

Hindermann W., Berndt A., Haas KM., Wunderlich H., Katenkamp D., Kosmehl H.
Immunohistochemical demonstration of the g 2 chain of laminin-5 in urinary bladder urothelial carcinoma (UC). Impact for diagnosis and prognosis.
Journal of Cancer Detection and Prevention 2003, 27(2):109-115
Vogel W., Berndt A., Müller A., Dahse R., Haas KM., Borsi L., Zardi L., KosmehlH.
Differential in vivo and in vitro expression of ED-B+ fibronectin in adult human haematopoiesis.
International Journal of Molecular Medicine 2003, 12(6):831-837
Kriegsmann J., Berndt A., Hansen T., Borsi L., Zardi L., Bräuer R., Petrow P.K., Otto M., Kirkpatrick C.J., Gay S., Kosmehl H.
Expression of fibronectin splice variants and oncofetal glycosylated fibronectin in the synovial membranes of patients with rheumatoid arthritis and osteoarthritis.
Rheumatology International 2003, DOI 10.1007/s00296-003-0316-1
Hyckel P., Schleier P., Meerbach A., Berndt A., Kosmehl H., Wutzler P.
The therapy of virus-associated epithelial tumors of the face and the lips in organ transplant recipients.
Medical Microbiology and Immunology 2003; 192(3):171-176
Borsi L., Balza E., Carnemolla B., Sassi F., Castellani P., Berndt A., Kosmehl H., Biro A., Siri A., Orecchia P., Grassi J., Neri D., Zardi L.
Selective targeted delivery of TNFa to tumor blood vessels.
Blood 2003, 102(13): 4384-4392
Halin C., Gafner V., Villani ME., Borsi L., Berndt A., Kosmehl H., Zardi L., Neri D.
Synergistic therapeutic effects of a tumor targetting antibody fragment, fused to interleukin-12 and to tumor necrosis factor alpha.
Cancer Research 2003; 63:3202-3210

2004

Katenkamp K., Berndt A., Hindermann W., Wunderlich H., Haas KM., Borsi L., Zardi L., Kosmehl H.
Synthesis and protein distribution of the unspliced tenascin-C isoform in prostatic adenocarcinoma.
J Pathol 2004, 203:771-779
Schleier P., Berndt A., Voth M., Herzau M., Koloßa S., Zenk W., Dietel W., Gawellek M., Kosmehl H.
Möglichkeiten und Grenzen der Fluoreszenzdiagnostik und photodynamischen Therapie des Mundhöhlenkarzinoms.
Deutsche Zahnärztliche Zeitschrift 2004, 59(5)
Schleier P., Hyckel P., Berndt A., Bode H.P., Albrecht V., Hindermann W., Kosmehl H., Zenk W., Schumann D.
Photodynamic therapy of virus-associated epithelial tumours of the face in organ transplant recipients.
Cancer Research and Clinical Oncology 2004, 130:29-284
Hilger I., Leistner Y., Berndt A., Fritsche C., Haas K.M., Kosmehl H., Kaiser W.A.
Near-infrared fluorescence imaging of HER-2 protein over-expression in tumour cells.
Eur Radiol 2004, 14:1124-1129
Hakim S.G., Lauer I., Nadrowitz R., Berndt A., Kosmehl H., Sieg P.
Re-distribution of tenascin-C in the parotid acinar cells. An early marker of radiation-induced damage of salivary glands?
Anticancer Res 2004, 24:2841-2846
Beetz C., Brodhun M., Moutzouris K., Kientopf M., Berndt A., Lehnert D., Deufel T., Bastmeyer M., Schickel J.
Identification of nuclear localisation sequences in spastin (SPG4) using a novel Tetra-GFP reporter system.
Biochemical and Biophysical Research Communications 2004, 319: 1079-1084
Kriegsmann J, Berndt A, Hansen T, Borsi L, Zardi L, Brauer R, Petrow PK, Otto M, Kirkpatrick CJ, Gay S, Kosmehl H.
Expression of fibronectin splice variants and oncofetal glycosylated fibronectin in the synovial membranes of patients with rheumatoid arthritis and osteoarthritis.
(2004) Rheumatol Int 24:25-33

2005

Hyckel P., Berndt A., Schleier P., Clement J., Beensen V., Peters H., Kosmehl H.
Cherubism - new hypotheses on pathogenesis and consequences.
Journal of Cranio-Maxillofacial Surgery 2005, 33:61-68
Grün K., Markova B., Böhmer F.D., Berndt A., Tsai Y.J., Blüthmann H., Leipner C.
Elevated expression of PDGF-C in Coxsackievirus B3 (CVB3) - induced chronic myocarditis.
(2005) Eur Heart J 26:728-739
Ebbinghaus C., Ronca R., Kaspar M., Grabulovski D., Berndt A., Kosmehl H., Zardi L., Neri D.
An engineered vascular-targeting antibody-interferon g fusion protein for cancer therapy.
(2005) Int J Cancer 116:304-313
Katenkamp K., Richter P., Slatosch T., Katenkamp D., Berndt A.
Simultane t(X;18) FISH - und SYT/SSX RT-PCR - Analyse in der Diagnostik des Synovialsarkoms.
(2005) Pathologe 26:111-116
Richter P., Böhmer F.D., Hindermann W., Borsi L., Hyckel P., Schleier P., Katenkamp D., Kosmehl H., Berndt A.
Analysis of activated EGFR signalling pathways and their relation to laminin-5 g 2 chain expression in oral squamous cell carcinoma (OSCC).
(2005) Histochem Cell Biol 124:151-160

2006

Franz M., Hansen T., Richter P., Borsi L., Böhmer FD., Hyckel P., Schleier P., Katenkamp D., Zardi L., Kosmehl H., Berndt A.
Complex formation of the laminin-5 gamma2 chain and large unspliced tenascin-C in oral squamous cell carcinoma in vitro and in situ: implications for sequential modulation of extracellular matrix in the invasive tumor front.
(2006) Histochem Cell 126(1):125-31.
Schleier P., Wolf C., Siebert H., Berndt A., Schumann D.
Bidirektionale und unidirektionale Distraktion von Alveolarfortsatzdefekten: Vergleichende klinische Studie.
(2006) Dtsch. Z. Mund Kiefer GesichtsChir. 10(2):95-101
Berndt A., Anger K., Richter P., Borsi L., Brack S., Silacci M., Franz M., Wunderlich H., Gajda M., Zardi L., Neri D., Kosmehl H.
mRNA expression and protein distribution of tenascin-C splicing domains in human urinary bladder carcinomas.
(2007) J Cancer Res Clin Oncol 2006 132 (8):537-46
Driemel O, Berndt A, Hartmann A, Mueller-Richter UD, Bauer R, Reichert TE, Kosmehl H.
Clinical and immunohistochemical findings of intra- and extraoral angiosarcomas.
(2007) Mund Kiefer Gesichtschir 10:239-247
Driemel O, Dahse R, Berndt A, Pistner H, Hakim SG, Zardi L, Reichert TE, Kosmehl H.
High-molecular tenascin-C as an indicator of atypical cells in oral brush biopsies. (2007) Clin Oral Investig 11:93-99

2007

Franz M., Hansen T., Borsi L., Geier C., Hyckel P., Schleier P., Richter P., Altendorf-Hofmann A., Kosmehl H., Berndt A.
A quantitative colocalization anaysis of large unspliced Tenascin-CL and Laminin-5 / gamma2-chain in basement membranes of oral squamous cell carcinoma by confocal laser scanning microscopy.
(2007) J Oral Pathol 36(1):6-11.
Franz M., Berndt A., Wehrhan F., Schleier P., Clement J., Hyckel P.
Ectopic bone formation as a complication of surgical rehabilitation in patients with Moebius syndrome.
(2007) J Craniomaxillofac Surg 35 (4-5): 252-257
Driemel O, Dahse R, Berndt A, Pistner H, Hakim SG, Zardi L, Reichert TE, Kosmehl H
High-molecular tenascin-C as an indicator of atypical cells in oral brush biopsies.(2007) Clin Oral Investig 11:93-99
Driemel O, Kosmehl H, Rosenhahn J, Berndt A, Reichert TE, Zardi L, Dahse R
Expression analysis of extracellular matrix components in brush biopsies of oral lesions.
(2007) Anticancer Res 27:1565-1570
Schleier P, Berndt A, Kolossa S, Zenk W, Hyckel P, Schultze-Mosgau S
Comparison of aminolevulinic acid (ALA)-thermogel-PDT with methyl-ALA-thermogel-PDT in basal cell carcinoma.
(2007) Photodiag Photodyn Ther 4:197-20
Schleier P, Wolf C, Siebert H, Shafer D, Freilich M, Berndt A, Schumann D
Treatment options in distraction osteogenesis therapy using a new bidirectional distractor system
Int J Oral Maxillofac Implants (2007); 22(3):408-16

2008

Franz M., Bahrmann P., Berndt A., Isecke A., Gummert J., Figulla H.R., Brehm, B.R.
Indikationen zur herzchirurgischen Therapie bei Endokarditis: Fallbeschreibung und Allgemeine Aspekte.
Med Klinik 2008;103:349-55 (Nr.5)
Richter P, Junker K, Franz M, Berndt A, Geyer C, Gajda M, Kosmehl H, Berndt A, Wunderlich H.
IIICS de novo glycosylated fibronectin as a marker for invasiveness in urothelial carcinoma of the urinary bladder (UBC).
(2008) J Cancer Res Clin Oncol 134:1059-1065
Leipner C, Grun K, Muller A, Buchdunger E, Borsi L, Kosmehl H, Berndt A, Janik T, Uecker A, Kiehntopf M, Bohmer FD
Imatinib mesylate attenuates fibrosis in coxsackievirus B3 (CVB3)- induced chronic myocarditis.
Cardiovasc Res. 2008; 79, 118-126
Dahse C, Berndt A, Kosmehl K
PCR-based testing for therapy-related EGFR mutations with Non-small Cell Lung Cancer.
Anticancer research 2008; 28(4B): 2265-70
Dahse R, Berndt A, Dahse AK, Kosmehl H
Two allele-specific PCR assays for screening epidemal growth factor receptor gene hotspot mutations in lung adenocarcinoma.
(2008)Molecular Medicine Reports [in press]
Berndt An, Mueller J, Borsi L, Kosmehl H, Methner U, Berndt Al
Reorganisation of the caceal extracellular matrix upon Salmonella infection - relation between bacterial invasiveness and expression of virulence genes.
(2008) Vet Microbiol 133:123-137
Driemel O, Müller-Richter UDA, Hakim SG, Bauer R, Berndt A, Kleinheinz J, Reichert TE, Kosmehl H
Oral acantholytic squamous cell carcinoma shares clinical and histological features with angiosarcoma.
(2008) Head Face Med 4:17

2009

Jandt E, Mutschke O, Mahboobi S, Uecker A, Platz R, Berndt A, Böhmer FD, Figulla HR, Werner GS
Stent-based release of a selective PDGF-receptor blocker from the bis-indolylmethanon class inhibits restenosis in the rabbit animal model. Vascul Pharmacol.
2009 Nov 29. [Epub ahead of print] PubMed PMID: 19951743.
Cesca M, Frapolli R, Berndt A, Scarlato V, Richter P, Kosmehl H, D'Incalci M, Ryan AJ, Giavazzi R
The effects of vandetanib on paclitaxel tumor distribution and antitumor activity in a xenograft model of human ovarian carcinoma.
(2009) Neoplasia 11:1155-64
Franz M, Berndt A, Altendorf-Hofmann A, Fiedler N, Richter P, Schumm J, Fritzenwanger M, Figulla HR, Brehm BR
Serum levels of large tenascin-C variants, matrix metalloproteinase-9, and tissue inhibitors of matrix metalloproteinases in concentric versus eccentric left ventricular hypertrophy.
(2009) Eur J Heart Fail 11:1057-1062
Dahse R, Kromeyer-Hauschild K, Berndt A, Kosmehl H
No incidence of BRAF mutations in salivary gland carcinomas--implications for anti-EGFR therapies.
(2009) J Biomed Biotechnol 2009:501736
Dahse R, Driemel O, Schwarz S, Kromeyer-Hauschild K, Berndt A, Kosmehl H
KRAS status and epidermal growth factor receptor expression as determinants for anti-EGFR therapies in salivary gland carcinomas.
(2009) Oral Oncol 45:826-829
Richter P, Tost M, Franz M, Altendorf-Hofmann A, Junker K, Borsi L, Neri D, Kosmehl H, Wunderlich H, Berndt A
B and C domain containing tenascin-C: urinary markers for invasiveness of urothelial carcinoma of the urinary bladder?
(2009) J Cancer Res Clin Oncol 135:1351-1358
Franz M, Spiegel K, Umbreit C, Richter P, Codina-Canet C, Berndt A, Altendorf-Hofmann A, Koscielny S, Hyckel P, Kosmehl H, Virtanen I, Berndt A
Expression of Snail is associated with myofibroblast phenotype development in oral squamous cell carcinoma.
(2009) Histochem Cell Biol 131:651-660
Dahse R, Driemel O, Schwarz S, Dahse J, Kromeyer-Hauschild K, Berndt A, Kosmehl H
Epidermal growth factor receptor kinase domain mutations are rare in salivary gland carcinomas.
(2009) Br J Cancer 100:623-625

2010

Berndt A, Kollner R, Richter P, Franz M, Voigt A, Borsi L, Giavazzi R, Neri D, Kosmehl H
A comparative analysis of oncofetal fibronectin and tenascin-C incorporation in tumour vessels using human recombinant SIP format antibodies.
(2010) Histochem Cell Biol 133:467-475
Johannsen M, Spitaleri G, Curigliano G, Roigas J, Weikert S, Kempkensteffen C, Roemer A, Kloeters C, Rogalla P, Pecher G, Miller K, Berndt A, Kosmehl H, Trachsel E, Kaspar M, Lovato V, Gonzalez-Iglesias R, Giovannoni L, Menssen HD, Neri D, de Braud F
The tumour-targeting human L19-IL2 immunocytokine: Preclinical safety studies, phase I clinical trial in patients with solid tumours and expansion into patients with advanced renal cell carcinoma.
(2010) Eur J Cancer
Franz M, Brehm BR, Richter P, Gruen K, Neri D, Kosmehl H, Hekmat K, Renner A, Gummert J, Figulla HR, Berndt A
Changes in extra cellular matrix remodelling and re-expression of fibronectin and tenascin-C splicing variants in human myocardial tissue of the right atrial auricle: implications for a targeted therapy of cardiovascular diseases using human SIP format antibodies.
(2010) J Mol Histol 41:39-50
Escher N, Ernst G, Melle C, Berndt A, Clement JH, Junker K, Friedrich K, Guntinas-Lichius O, von Eggeling F
Comparative proteomic analysis of normal and tumor stromal cells by tissue on chip based mass spectrometry (toc-MS).
(2010) Diagn Pathol 5:10
Knosel T, Heretsch S, Altendorf-Hofmann A, Richter P, Katenkamp K, Katenkamp D, Berndt A, Petersen I
TLE1 is a robust diagnostic biomarker for synovial sarcomas and correlates with t(X;18): analysis of 319 cases.
(2010) Eur J Cancer 46:1170-1176
Jandt E, Mutschke O, Mahboobi S, Uecker A, Platz R, Berndt A, Bohmer FD, Figulla HR, Werner GS
Stent-based release of a selective PDGF-receptor blocker from the bis-indolylmethanon class inhibits restenosis in the rabbit animal model.
(2010) Vascul Pharmacol 52:55-62
Franz M, Wolheim A, Richter P, Umbreit C, Dahse R, Driemel O, Hyckel P, Virtanen I, Kosmehl H, Berndt A
Stromal laminin chain distribution in normal, hyperplastic and malignant oral mucosa: relation to myofibroblast occurrence and vessel formation.
(2010) J Oral Pathol Med 39:290-298
Franz M, Grun K, Richter P, Brehm BR, Fritzenwanger M, Hekmat K, Neri D, Gummert J, Figulla HR, Kosmehl H, Berndt A, Renner A
Extra cellular matrix remodelling after heterotopic rat heart transplantation: gene expression profiling and involvement of ED-A+ fibronectin, alpha-smooth muscle actin and B+ tenascin-C in chronic cardiac allograft rejection.
(2010) Histochem Cell Biol 134:503-517

2011

Baldinger A, Brehm BR, Richter P, Bossert T, Gruen K, Hekmat K, Kosmehl H, Neri D, Figulla HR, Berndt A, Franz M
Comparative analysis of oncofetal fibronectin and tenascin-C expression in right atrial auricular and left ventricular human cardiac tissue from patients with coronary artery disease and aortic valve stenosis.
(2011) Histochem Cell Biol 135:427-441
Cui T, Chen Y, Knosel T, Yang L, Zoller K, Galler K, Berndt A, Mihlan M, Zipfel PF, Petersen I
Human complement factor H is a novel diagnostic marker for lung adenocarcinoma. (2011) Int J Oncol 39:161-168
Enkelmann A, Heinzelmann J, von Eggeling F, Walter M, Berndt A, Wunderlich H, Junker K
Specific protein and miRNA patterns characterise tumour-associated fibroblasts in bladder cancer.
(2011) J Cancer Res Clin Oncol 137:751-759
Franz M, Berndt A, Grun K, Richter P, Kosmehl H, Neri D, Gummert J, Figulla HR, Brehm BR, Renner A
Expression of extra domain A containing fibronectin in chronic cardiac allograft rejection.
(2011) J Heart Lung Transplant 30:86-94
Gecks T, Junker K, Franz M, Richter P, Walther M, Voigt A, Neri D, Kosmehl H, Wunderlich H, Kiehntopf M, Berndt A
B domain containing Tenascin-C: A new urine marker for surveillance of patients with urothelial carcinoma of the urinary bladder?
(2011) Clin Chim Acta
Richter P, Umbreit C, Franz M, Berndt A, Grimm S, Uecker A, Bohmer FD, Kosmehl H
EGF/TGFbeta1 co-stimulation of oral squamous cell carcinoma cells causes an epithelial-mesenchymal transition cell phenotype expressing laminin 332.
(2011) J Oral Pathol Med 40:46-54
Weisheit S, Schafer C, Mertens C, Berndt A, Liebmann C
PKCepsilon acts as negative allosteric modulator of EGF receptor signalling.
(2011) Cell Signal 23:436-44

2012

Briest F, Berndt A, Clement J, Junker K, Eggeling F, Grimm S, Friedrich K
Tumor-stroma interactions in tumorigenesis: lessons from stem cell biology.
(2012) Front Biosci (Elite Ed) 4:1871-1887
Franz M, Neri D, Berndt A
Chronic cardiac allograft rejection: critical role of ED-A(+) fibronectin and implications for targeted therapy strategies.
(2012) J Pathol 226:557-561
Galler K, Junker K, Franz M, Hentschel J, Richter P, Gajda M, Gohlert A, von Eggeling F, Heller R, Giavazzi R, Neri D, Kosmehl H, Wunderlich H, Berndt A
Differential vascular expression and regulation of oncofetal tenascin-C and fibronectin variants in renal cell carcinoma (RCC): implications for an individualized angiogenesis-related targeted drug delivery.
(2012) Histochem Cell Biol 137:195-204
Bello E, Taraboletti G, Colella G, Zucchetti M, Forestieri D, Licandro SA, Berndt A, Richter P, D'Incalci M, Cavalletti E, Giavazzi R, Camboni G, Damia G
The tyrosine kinase inhibitor E-3810 combined with paclitaxel inhibits the growth of advanced-stage triple-negative breast cancer xenografts.
(2012) Mol Cancer Ther 12:131-140
Moschetta M, Pretto F, Berndt A, Galler K, Richter P, Bassi A, Oliva P, Micotti E, Valbusa G, Schwager K, Kaspar M, Trachsel E, Kosmehl H, Bani MR, Neri D, Giavazzi R
Paclitaxel enhances therapeutic efficacy of the F8-IL2 immunocytokine to EDA-fibronectin-positive metastatic human melanoma xenografts.
(2012) Cancer Res 72:1814-1824
Schulte J, Weidig M, Balzer P, Richter P, Franz M, Junker K, Gajda M, Friedrich K, Wunderlich H, Ostman A, Petersen I, Berndt A
Expression of the E-cadherin repressors Snail, Slug and Zeb1 in urothelial carcinoma of the urinary bladder: relation to stromal fibroblast activation and invasive behaviour of carcinoma cells.
(2012) Histochem Cell Biol 138:847-860

2013

Franz M, Berndt A, Neri D, Galler K, Grun K, Porrmann C, Reinbothe F, Mall G, Schlattmann P, Renner A, Figulla HR, Jung C, Kuthe F
Matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1, B(+) tenascin-C and ED-A(+) fibronectin in dilated cardiomyopathy: Potential impact on disease progression and patients' prognosis.
(2013) International journal of cardiology 168:5344-5351
Franz M, Hilger I, Grun K, Kossatz S, Richter P, Petersen I, Jung C, Gummert J, Figulla HR, Kosmehl H, Neri D, Berndt A, Renner A
Selective imaging of chronic cardiac rejection using a human antibody specific to the alternatively spliced EDA domain of fibronectin.
(2013) The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 32:641-650

2014

Berndt A, Büttner R, Gühne S, Gleinig A, Richter P, Chen Y, Franz M, Liebmann C.
Effects of activated fibroblasts on phenotype modulation, EGFR signalling and cell cycle regulation in OSCC cells.
Exp Cell Res. 2014 Apr 1;322(2):402-14
Franz M, Matusiak-Brückner M, Richter P, Grün K, Ziffels B, Neri D, Maschek H, Schulz U, Pfeil A, Jung C, Figulla HR, Gummert J, Berndt A, Renner A.
De novo expression of fetal ED-A(+) fibronectin and B (+) tenascin-C splicing variants in human cardiac allografts: potential impact for targeted therapy of rejection.
J Mol Histol. 2014 Oct;45(5):519-32

2015

Franz M, Jung C, Lauten A, Figulla HR, Berndt A.
Tenascin-C in cardiovascular remodeling: potential impact for diagnosis, prognosis estimation and targeted therapy.
Cell Adh Migr. 2015;9(1-2):90-5
Berndt A, Richter P, Kosmehl H, Franz M.
Tenascin-C and carcinoma cell invasion in oral and urinary bladder cancer.
Cell Adh Migr. 2015;9(1-2):105-11
Grimm S, Jennek S, Singh R, Enkelmann A, Junker K, Rippaus N, Berndt A, Friedrich K.
Malignancy of bladder cancer cells is enhanced by tumor-associated fibroblasts through a multifaceted cytokine-chemokine loop.
Exp Cell Res. 2015 Jul 1;335(1):1-11
Franz M, Doll F, Grün K, Richter P, Köse N, Ziffels B, Schubert H, Figulla HR, Jung C, Gummert J, Renner A, Neri D, Berndt A.
Targeted delivery of interleukin-10 to chronic cardiac allograft rejection using a human antibody specific to the extra domain A of fibronectin.
Int J Cardiol. 2015 Sep 15;195:311-22

2016

Cesca M, Morosi L, Berndt A, Fuso Nerini I, Frapolli R, Richter P, Decio A, Dirsch O, Micotti E, Giordano S, D'Incalci M, Davoli E, Zucchetti M, Giavazzi R.
Bevacizumab-Induced Inhibition of Angiogenesis Promotes a More Homogeneous Intratumoral Distribution of Paclitaxel, Improving the Antitumor Response.
Mol Cancer Ther. 2016 Jan;15(1):125-35
Büttner R, Berndt A, Valkova C, Richter P, Korn A, Kosan C, Liebmann C.
Myofibroblasts have an impact on expression, dimerization and signaling of different ErbB receptors in OSCC cells.
J Recept Signal Transduct Res. 2016 Apr 6:1-13
Geweiler J, Inhestern J, Berndt A, Guntinas-Lichius O.
Parameters of Stromal Activation and Epithelial to Mesenchymal Transition as Predictive Biomarkers for Induction Chemotherapy in Patients With Locally Advanced Oral Cavity and Oropharyngeal Squamous Cell Cancer.
Clin Exp Otorhinolaryngol. 2016 Jul 2
Ziffels B, Ospel J, Grün K, Neri D, Pfeil A, Fritzenwanger M, Figulla HR, Jung C, Berndt A, Franz M
Detection of Soluble ED-A+ Fibronectin and Evaluation as Novel Serum Biomarker for Cardiac Tissue Remodeling
Disease Markers (2016), Article ID 3695454, doi.org/10.1155/2016/3695454
Franz M, Grün K, Betge S, Rohm I, Ndongson-Dongmo B, Bauer R, Schulze PC, Lichtenauer M, Petersen I, Neri D, Berndt A, Jung C. Lung tissue remodelling in MCT-induced pulmonary hypertension: a proposal for a novel scoring system and changes in extracellular matrix and fibrosis associated gene expression. Oncotarget. 2016 Dec 6;7(49):81241-81254. doi: 10.18632/oncotarget.13220.

2017

Jung C, Grün K, Betge S, Pernow J, Kelm M, Muessig J, Masyuk M, Kuethe F, Ndongson-Dongmo B, Bauer R, Lauten A, Schulze PC, Berndt A, Franz M. Arginase Inhibition Reverses Monocrotaline-Induced Pulmonary Hypertension. Int J Mol Sci. 2017 Jul 25;18(8). pii: E1609. doi: 10.3390/ijms18081609.
Rohm I, Grün K, Müller LM, Kretzschmar D, Fritzenwanger M, Yilmaz A, Lauten A, Jung C, Schulze PC, Berndt A, Franz M. Increased Serum Levels of Fetal Tenascin-C Variants in Patients with Pulmonary Hypertension: Novel Biomarkers Reflecting Vascular Remodeling and Right Ventricular Dysfunction? Int J Mol Sci. 2017 Nov 8;18(11). pii: E2371. doi: 10.3390/ijms18112371.