Mercator
Prof. Dr. med. Josep Dalmau
Prof. Dr. med Masaki Fukata
Principal Investigators
Prof. Dr. med. Christian Geis
Speaker and Principal Investigator of projects P1, P6 and PZ
P1: Direct and acute effects of human monoclonal anti-GluN1 autoantibodies on NMDA receptor channel function
P6: Molecular mechanisms and in-vivo functional effects of antibodies in GABAB receptor autoimmune encephalitis
Prof. Dr. med. Stefan Hallermann
Deputy Speaker and Principal Investigator of projects P2 and P8
P2: LGI1 antibody induced pathophysiology at axon initial segments and presynaptic nerve terminals
P8: Antibody neutralization for treatment of autoimmune encephalitis
Carl-Ludwig-Institute for Physiology
University Leipzig
Liebigstr. 27
04103 Leipzig
Germany
Phone: +49 (0) 341 9 71 55 00
Fax: +49 (0) 341 9 71 55 09
Email:
Web:http://physiologie.medizin.uni-leipzig.de
Prof. Dr. med. Manfred Heckmann
Principal Investigator of project P1
P1: Direct and acute effects of human monoclonal anti-GluN1 autoantibodies on NMDA receptor channel function
Institute for Physiology (focus: Neurophysiology)
University of Würzburg
Röntgenring 9,
97070 Würzburg
Assoc.Prof. PD Dr. med. Romana Höftberger
Principal Investigator of project P4
P4: Impact of IgLON5 autoantibodies on cerebellar circuits and neuronal pathology in human patients and mouse models
Division of Neuropathology and Neurochemistry
Department of Neurology
Medical University of Vienna, 4J
Waehringer Guertel 18-20
1090 Vienna
Phone: +4314040055000
Fax: +43140400455110
EMail:
Web: www.meduniwien.ac.at/npc
Prof. Dr. rer. nat. Michael Hust
Principal Investigator of project P8
P8: Antibody neutralization for treatment of autoimmune encephalitis
Institute for Biochemistry,
Biotechnology and Bioinformatics, Department Biotechnology,
Technische Universität Braunschweig
Spielmannstr. 7
38106 Braunschweig
Germany
Prof. Dr. med. Angela Kaindl
Principal Investigator of project P7
P7: Developmental defects caused by transplacental transmission of autoantibodies against NMDA receptors and further neuronal antigens
Department of Pediatric Neurology and Center for Chronically Sick Children
Charité – Universitatsmedizin Berlin
Augustenburger Platz 1
13353 Berlin
Germany
Prof. Dr. med. Knut Kirmse
Principal Investigator of project P7
P7: Developmental defects caused by transplacental transmission of autoantibodies against NMDA receptors and further neuronal antigens
Institute of Physiology
Department of Neurophysiology
University of Würzburg
Röntgenring 9
97070 Würzburg
Germany
Dr. rer. nat. Hans-Christian Kornau
Principal Investigator of project P6
P6: Molecular mechanisms and in-vivo functional effects of antibodies in GABAB receptor autoimmune encephalitis
CharitéCrossOver,
Deutsches Zentrum für Neurodegenerative
Erkrankungen e.V. (DZNE)
Charitéplatz 1, 10117 Berlin
Germany
Dr. med. Jakob Kreye
Principal Investigator of project P7
P7: Developmental defects caused by transplacental transmission of autoantibodies against NMDA receptors and further neuronal antigens
Charité – University Medicine Berlin, Department of Pediatric Neurology
and Center for Chronically Sick Children, and German Center for
Neurodegenerative Diseases (DZNE) Berlin
Augustenburger Platz 1, 13353 Berlin
Germany
Dr. Dr. med. Sabine Liebscher
Principal Investigator of project P4
P4: Impact of IgLON5 autoantibodies on cerebellar circuits and neuronal pathology in human patients and mouse models
Cellular Neurophysiology
Klinik für Neurologie, Universitätsklinik Köln
FLEX Gebäude
Weyertal 115C, 50931 Köln
Germany
&
Emmy Noether Research Group leader
Institute of Clinical Neuroimmunology
Klinikum der Universität München
Ludwig-Maximilians University Munich
Grosshaderner Str. 9, D-82152 Martinsried
Phone: +49 89 2180 71659
EMail:
Web: https://www.neuroimmunology-munich.de/our-labs/liebscher-lab/62208d74399bdb46
PD Dr. med. Harald Pruess
Principal Investigator of projects P3
P3: Origin and Diversity of Pathogenic Human Monoclonal Antibodies and T cells in Tumor-associated Autoimmune Neurological Disorders
German Center for Neurodegenerative Diseases (DZNE) Berlin
Charité – Universitatsmedizin Berlin
Chariteplatz 1
10117 Berlin
Germany
Prof. Dr. rer. nat. Britta Qualmann
Principal Investigator of project P5
P5: Glycine receptor autoantibodies and spinal disinhibition
Jena University Hospital
Institute for Biochemistry I
Nonnenplan 2-4, 07743 Jena
Germany
Prof. Dr. rer. nat. Markus Sauer
Principal Investigator of project P2
P2: LGI1 antibody induced pathophysiology at axon initial segments and presynaptic nerve terminals
Department of Biotechnology and Biophysics
Biocenter
University of Würzburg
Am Hubland
97074 Würzburg
Germany
Phone: +49 931 3188687
EMail:
Web: www.super-resolution.de
Prof. Dr. med. Christoph Schmidt-Hieber
Principal Investigator of project P6
P6: Molecular mechanisms and in-vivo functional effects of antibodies in GABAB receptor autoimmune encephalitis
Institut für Physiologie I
Am Teichgraben 8
07743 Jena
Germany
Phone: +49 (0) 3641 9 39 76 01
Fax: +49 (0) 3641 9 39 76 02
Email:
Web: https://www.uniklinikum-jena.de/physiologie1/
Prof. Dr. med. Ryuichi Shigemoto
Principal Investigator of project P2
P2: LGI1 antibody induced pathophysiology at axon initial segments and presynaptic nerve terminals
Institute of Science and Technology Austria (IST Austria)
Am Campus 1
A – 3400 Klosterneuburg
Austria
Prof. Dr. rer. nat. Carmen Villmann
Principal Investigator of project P5
P5: Glycine receptor autoantibodies and spinal disinhibition
Institute of Clinical Neurobiology
University Hospital Würzburg,
Versbacherstr. 5
97078 Würzburg
Germany
Prof. Dr. rer. nat. Hedda Wardemann
Principal Investigator of project P3
P3: Origin and Diversity of Pathogenic Human Monoclonal Antibodies and T cells in Tumor-associated Autoimmune Neurological Disorders
B Cell Immunology, Head of Division
German Cancer Research Center (DKFZ)
Im Neuenheimer Feld 280
69120 Heidelberg
Germany
Phone: +49 6221 42 12 70
Email:
Web: www.dkfz.de
Former Principal investigators (1st funding period)
Prof. Dr. med. Dietmar Schmitz
Principal Investigator of project P6
P6: Effects of GABAB receptor antibodies on neuronal signalling and hippocampal function
Neuroscience Research Center (NWFZ)
Charité - Universitatsmedizin Berlin
Chariteplatz 1
10117 Berlin
Germany
Prof. Dr. med. Claudia Sommer
Young Researcher
Dr. Isabel Bünger
Member of project P7
P7: Developmental defects caused by transplacental transmission of autoantibodies against NMDA receptors and further neuronal antigens
Charité – University Medicine Berlin, Department of Pediatric Neurology
and Center for Chronically Sick Children, and German Center for
Neurodegenerative Diseases (DZNE) Berlin
Augustenburger Platz 1, 13353 Berlin
Germany
Dianne Gnann
Member of project P8
P8: Antibody neutralization as a potential treatment for NMDA receptor encephalitis
Institute for Biochemistry,
Biotechnology and Bioinformatics, Department Biotechnology,
Technische Universität Braunschweig
Spielmannstr. 7
38106 Braunschweig
Dr. Tom Floßmann
Principal Investigator of project P6
P6: Molecular mechanisms and in-vivo functional effects of antibodies in GABAB receptor autoimmune encephalitis
Institut für Physiologie I
Am Teichgraben 8
07743 Jena
Germany
Email:
Web: https://www.uniklinikum-jena.de/physiologie1/
Jackson Fontaine
Member of project P4
P4: Impact of IgLON5 autoantibodies on cerebellar circuits and neuronal pathology in human patients and mouse models
Institute of Clinical Neuroimmunology
Klinikum der Universität München
Ludwig-Maximilians University Munich
Grosshaderner Str. 9, D-82152 Martinsried
Margarita Habib, PhD student
Member of project P5
P5: Glycine receptor autoantibodies and spinal disinhibition
Institute of Clinical Neurobiology
University Hospital Würzburg,
Versbacherstr. 5
97078 Würzburg
Germany
Toni Kirmann, PhD student
Member of project P8
P8: Antibody neutralization as a potential treatment for NMDA receptor encephalitis
Carl-Ludwig-Institute for Physiology
University Leipzig
Liebigstr. 27
04103 Leipzig
Germany
Email:
Web:http://physiologie.medizin.uni-leipzig.de
Eleonora Loi, PhD student
Member of project P6
P6: Effects of GABAB receptor antibodies on neuronal signalling and hippocampal function
Section Translational Neuroimmunology
Jena University Hospital
Department of Neurology
Am Klinikum1
07747 Jena
Email:
Web: https://www.uniklinikum-jena.de/neuroimmunologie
Dr. Jana Nerlich
Member of project P2
P2: LGI1 antibody induced pathophysiology in presynaptic nerve terminals
Carl-Ludwig-Institute for Physiology
University Leipzig
Liebigstr. 27
04103 Leipzig
Germany
Email:
Web:http://physiologie.medizin.uni-leipzig.de
Dr. rer. nat Jacqueline-Claire Montanaro-Punzengruber
Member of project P2
P2: LGI1 antibody induced pathophysiology in presynaptic nerve terminals
Institute of Science and Technology Austria (IST Austria)
Am Campus 1
A – 3400 Klosterneuburg
Austria
Sophie Nitsch, PhD student
Member of project P4
P4: Immunopathology and synaptopathy in human brain tissue and novel animal models of LGI1 encephalitis
Division of Neuropathology and Neurochemistry
Department of Neurology
Medical University of Vienna, 4J
Waehringer Guertel 18-20
1090 Vienna
EMail:
Web: www.meduniwien.ac.at/npc
Dr. med. Marc Nikolaus
Member of project P7
P7: Developmental and synaptic defects caused by transplacental transmission of NMDA receptor antibodies
Charité – Universitatsmedizin Berlin
Augustenburger Platz 1
13353 Berlin
Germany
Stefan Sachs, PhD student
Member of project P2
P2: LGI1 antibody induced pathophysiology in presynaptic nerve terminals
Department of Biotechnology and Biophysics
Biocenter
University of Würzburg
Am Hubland
97074 Würzburg
Germany
Abdulla Taha, PhD student
Member of project P1
P1: Effects of human monoclonal anti-GluN1 autoantibodies on NMDA receptor channel function
Section Translational Neuroimmunology
Jena University HospitalDepartment of Neurology
Am Klinikum
107747
Jena
Email:
Web: https://www.uniklinikum-jena.de/neuroimmunologie
Arash Sammiee, PhD student
Member of project P7
P7: Developmental and synaptic defects caused by transplacental transmission of NMDA receptor antibodies
Jena University Hospital
Hans-Berger Department of Neurology
AG Bioimaging
Am Klinikum 1
07747 Jena
Germany
Alina Schneider, PhD student
Member of project P3
P3: Origin and Diversity of Pathogenic Human Monoclonal Antibodies and T cells in Tumor-associated Autoimmune Neurological Disorders
German Cancer Research Center (DKFZ)
Im Neuenheimer Feld 280
69120 Heidelberg
Germany
Email:
Web: www.dkfz.de
Jing Yu-Strzelcyk, PhD student
Member of project P1
P1: Effects of human monoclonal anti-GluN1 autoantibodies on NMDA receptor channel function
Institute for Physiology (focus: Neurophysiology)
University of Würzburg
Röntgenring 9,
97070 Würzburg
Dr .Rosa Rößling
associated members
Anna-Lena Eckes, PhD student
Member of project P5
P5: Glycine receptor autoantibodies and spinal disinhibition
Institute of Clinical Neurobiology
University Hospital Würzburg,
Versbacherstr. 5
97078 Würzburg
Germany
Janna Eilts
Member of project P2
P2: LGI1 antibody induced pathophysiology in presynaptic nerve terminals
Department of Biotechnology and Biophysics
Biocenter
University of Würzburg
Am Hubland
97074 Würzburg
Germany
Dr. Shiqiang Gao
Member of project P1
P1: Effects of human monoclonal anti-GluN1 autoantibodies on NMDA receptor channel function
Institute for Physiology (focus: Neurophysiology)
University of Würzburg
Röntgenring 9,
97070 Würzburg
Dr. rer. nat. Holger Haselmann
Member of project P1
P1: Effects of human monoclonal anti-GluN1 autoantibodies on NMDA receptor channel function
Section Translational Neuroimmunology
Jena University HospitalDepartment of Neurology
Am Klinikum
107747
Jena
Email:
Web: https://www.uniklinikum-jena.de/neuroimmunologie
PD Dr. Ellen Knierim
Member of project P7
P7: Developmental and synaptic defects caused by transplacental transmission of NMDA receptor antibodies
Department of Pediatric Neurology and Center for Chronically Sick Children
Charité – Universitatsmedizin Berlin
Augustenburger Platz 1
13353 Berlin
Germany
Myrtill Majoros, research.assistant
member of project P6
P6: Molecular mechanisms and in-vivo functional effects of antibodies in GABAB receptor autoimmune encephalitis
Institut für Physiologie I
Am Teichgraben 8
07743 Jena
Germany
Email:
Web: https://www.uniklinikum-jena.de/physiologie1/
Dr. med. Marc Nikolaus
Member of project P7
P7: Developmental and synaptic defects caused by transplacental transmission of NMDA receptor antibodies
Charité – Universitatsmedizin Berlin
Augustenburger Platz 1
13353 Berlin
Germany
MD Raphael Reinecke, PhD student
Member of project P4
P4: Immunopathology and synaptopathy in human brain tissue and novel animal models of LGI1 encephalitis
Division of Neuropathology and Neurochemistry
Department of Neurology
Medical University of Vienna, 4J
Waehringer Guertel 18-20
1090 Vienna
EMail:
Web: www.meduniwien.ac.at/npc
Gerda Ricken, M. Sc.
Member of project P4
P4: Immunopathology and synaptopathy in human brain tissue and novel animal models of LGI1 encephalitis
Division of Neuropathology and Neurochemistry
Department of Neurology
Medical University of Vienna, 4J
Waehringer Guertel 18-20
1090 Vienna
EMail:
Web: www.meduniwien.ac.at/npc
Dr. med. Eva Sedlin
Member of project P7
P7: Developmental and synaptic defects caused by transplacental transmission of NMDA receptor antibodies
Department of Pediatric Neurology and Center for Chronically Sick Children
Charité – Universitatsmedizin Berlin
Augustenburger Platz 1
13353 Berlin
Germany
Dr. rer. nat. Josefine Sell
Member of project P6
P6: Effects of GABAB receptor antibodies on neuronal signalling and hippocampal function
Section Translational Neuroimmunology
Jena University Hospital
Department of Neurology
Am Klinikum1
07747 Jena
Email:
Web: https://www.uniklinikum-jena.de/neuroimmunologie
Dr. rer. nat. Ilka Wahl
Member of project P3
P3: Origin and Diversity of Pathogenic Human Monoclonal Antibodies and T cells in Tumor-associated Autoimmune Neurological Disorders
German Cancer Research Center (DKFZ)
Im Neuenheimer Feld 280
69120 Heidelberg
Germany
Email:
Web: www.dkfz.de
Dr. rer. nat. Jessica Tröger
Principal Investigator of project P5
P5: Glycine receptor autoantibodies and spinal disinhibition
Jena University Hospital
Institute for Biochemistry I
Nonnenplan 2-4, 07743 Jena
Germany
Dr. rer. nat. Christian Werner
Member of project P2
P2: LGI1 antibody induced pathophysiology in presynaptic nerve terminals
Department of Biotechnology and Biophysics
Biocenter
University of Würzburg
Am Hubland
97074 Würzburg
Germany
Dr. Chuanqiang Zhang
former members
Verena Endmayr, M. Sc.
Member of project P4
P4: Immunopathology and synaptopathy in human brain tissue and novel animal models of LGI1 encephalitis
Division of Neuropathology and Neurochemistry
Department of Neurology
Medical University of Vienna, 4J
Waehringer Guertel 18-20
1090 Vienna
EMail:
Web: www.meduniwien.ac.at/npc
Felix Gsell, MD
Member of project P2
P2: LGI1 antibody induced pathophysiology in presynaptic nerve terminals
Carl-Ludwig-Institute for Physiology
University Leipzig
Liebigstr. 27
04103 Leipzig
Germany
Email:
Web:http://physiologie.medizin.uni-leipzig.de
Verena Hörlin, MD
Member of project P5
P5: Glycine receptor autoantibodies and spinal disinhibition
Institute of Clinical Neurobiology
University Hospital Würzburg,
Versbacherstr. 5
97078 Würzburg
Germany
Joshua Malapit, PhD student
Member of project P3
P3: Origin and diversity of pathogenic human monoclonal antibodies to the NMDA receptor
German Cancer Research Center (DKFZ)
Im Neuenheimer Feld 280
69120 Heidelberg
Germany
Phone: +49 6221 42 12 70
Email:
Web: www.dkfz.de
Inken Piro, PhD student
Member of project P5
P5: Glycine receptor autoantibodies and spinal disinhibition
Institute of Clinical Neurobiology
University Hospital Würzburg,
Versbacherstr. 5
97078 Würzburg
Germany
Gerda Ricken, M. Sc.
Member of project P4
P4: Immunopathology and synaptopathy in human brain tissue and novel animal models of LGI1 encephalitis
Division of Neuropathology and Neurochemistry
Department of Neurology
Medical University of Vienna, 4J
Waehringer Guertel 18-20
1090 Vienna
EMail:
Web: www.meduniwien.ac.at/npc
Dr. med. Andreas Ritzau-Jost
Member of project P2,8
P2: LGI1 antibody induced pathophysiology in presynaptic nerve terminals
P8: Antibody neutralization as a potential treatment for NMDA receptor encephalitis
Carl-Ludwig-Institute for Physiology
University Leipzig
Liebigstr. 27
04103 Leipzig
Germany
Email:
Web:http://physiologie.medizin.uni-leipzig.de
Stephan, Steinke, PhD student
Member of project P8
P8: Antibody neutralization as a potential treatment for NMDA receptor encephalitis
Institute for Biochemistry,
Biotechnology and Bioinformatics, Department Biotechnology,
Technische Universität Braunschweig
Spielmannstr. 7
38106 Braunschweig
Alexander Stumpf, PhD student
Member of project P6
P6: Effects of GABAB receptor antibodies on neuronal signalling and hippocampal function
Neuroscience Research Center (NWFZ)
Charité - Universitatsmedizin Berlin
Chariteplatz 1
10117 Berlin
Germany
Dr. med. Michael Winklehner
Member of project P4
P4: Immunopathology and synaptopathy in human brain tissue and novel animal models of LGI1 encephalitis
Division of Neuropathology and Neurochemistry
Department of Neurology
Medical University of Vienna, 4J
Waehringer Guertel 18-20
1090 Vienna
EMail:
Web: www.meduniwien.ac.at/npc
Vera Rauschenberger
Member of project P5