AG Optoelektrophysiologische Medizintechnik

2024
Human Electroretinography Shows Little Polarity Specificity Following Full-Field Ramp Adaptation.Freitag ST, Lengle MC, Klee S, Heinrich SP. Invest Ophthalmol Vis Sci. 2024 Aug 1;65(10):11. doi: 10.1167/iovs.65.10.11. PMID: 39106057; PMCID: PMC11309038.

How enoxaparin underdosing and sex contribute to achieving therapeutic anti-Xa levels.Tinchon A, Brait J, Klee S, Graichen U, Baumgartner C, Friedrich O, Freydl E, Oberndorfer S, Struhal W, Hain B, Waiß C, Stoiber D. Front Pharmacol. 2024 Jul 12;15:1377232. doi: 10.3389/fphar.2024.1377232. PMID: 39070792; PMCID: PMC11272590.

A novel function of STAT3β in suppressing interferon response improves outcome in acute myeloid leukemia.Edtmayer S, Witalisz-Siepracka A, Zdársky B, Heindl K, Weiss S, Eder T, Dutta S, Graichen U, Klee S, Sharif O, Wieser R, Győrffy B, Poli V, Casanova E, Sill H, Grebien F, Stoiber D. Cell Death Dis. 2024 May 28;15(5):369. doi: 10.1038/s41419-024-06749-9. PMID: 38806478; PMCID: PMC11133483.

CXCL13 as a biomarker in the diagnostics of European lyme Neuroborreliosis - A prospective multicentre study in Austria.Waiß C, Ströbele B, Graichen U, Klee S, Gartlehner J, Sonntagbauer E, Hirschbichler S, Tinchon A, Kacar E, Wuchty B, Novotna B, Kühn Z, Sellner J, Struhal W, Bancher C, Schnider P, Asenbaum-Nan S, Oberndorfer S. J Cent Nerv Syst Dis. 2024 May 2;16:11795735241247026. doi: 10.1177/11795735241247026. PMID: 38706882; PMCID: PMC11067428.

Favorable impact of PD1/PD-L1 antagonists on bone remodeling: an exploratory prospective clinical study and ex vivo validation.Gassner T, Chittilappilly C, Pirich T, Neuditschko B, Hackner K, Lind J, Aksoy O, Graichen U, Klee S, Herzog F, Wiesner C, Errhalt P, Pecherstorfer M, Podar K, Vallet S. J Immunother Cancer. 2024 May 3;12(5):e008669. doi: 10.1136/jitc-2023-008669. PMID: 38702145; PMCID: PMC11086513.

Prospective Analysis of Radiation-Induced Contrast Enhancement and Health-Related Quality of Life After Proton Therapy for Central Nervous System and Skull Base Tumors.Lütgendorf-Caucig C, Pelak M, Hug E, Flechl B, Surböck B, Marosi C, Mock U, Zach L, Mardor Y, Furman O, Hentschel H, Gora J, Fossati P, Stock M, Graichen U, Klee S, Georg P. Int J Radiat Oncol Biol Phys. 2024 Apr 1;118(5):1206-1216. doi: 10.1016/j.ijrobp.2024.01.007. Epub 2024 Jan 18. PMID: 38244874.

2023
Three-Dimensional Light Field Fundus Imaging: Automatic Determination of Diagnostically Relevant Optic Nerve Head Parameters. Wegert L, Schramm S, Dietzel A, Link D, Klee S. Transl Vis Sci Technol. 2023 Jul 3;12(7):21. doi: 10.1167/tvst.12.7.21. PMID: 37490305; PMCID: PMC10382995.

Editorial: Functional assessments of the ocular circulation. Heitmar R, Link D, Kotliar K, Schmidl D, Klee S. Front Med (Lausanne). 2023 Jun 8;10:1222022. doi: 10.3389/fmed.2023.1222022. PMID: 37359007; PMCID: PMC10285660.

Tadalafil zur Senkung des retinalen Venendrucks – ein neuer Ansatz in der Therapie des primären Offenwinkelglaukoms? [Tadalafil to lower retinal venous pressure-a new approach to treatment of primary open-angle glaucoma?]Kremmer S, Manoiu R, Smok C, Klee S, Anastassiou G, Link D, Stodtmeister R. Ophthalmologie. 2023 Oct;120(10):1045-1048. German. doi: 10.1007/s00347-023-01813-9. Epub 2023 Feb 17. PMID: 36806576.

2022

Application of a novel pneumatic intraocular pressure modulator: technical confounding of the tonographic effect. D Link, B Krauss, R Stodtmeister, E Nagel, W Vilser, S Klee, Investigative Ophthalmology & Visual Science 63 (7), 161–A0354-161–A0354       ,2022

Device and Method for Examining the Retinal Vascular Endothelial Function W Vilser, J Haueisen, K Sascha, L Dietmar, T Riemer, M Skorsetz, US Patent App. 17/553,764, 2022

Device and method for examining the retinal vascular endothelial function W Vilser, J Haueisen, K Sascha, L Dietmar, T Riemer, M Skorsetz, US Patent 11,224,342, 2022

Determination of the tonographic effect in the human eye using a pneumatic pressure modulator. D Link, B Krauss, R Stodtmeister, E Nagel, W Vilser, S Klee, Acta Ophthalmologica 100, 2022

Light‐field fundus imaging under astigmatism–An eye model study. S Schramm, A Dietzel, MC Blum, D Link, S Klee, Acta Ophthalmologica 100, 2022

Optic nerve head assessment in Light‐field fundus images–A case study. A Dietzel, S Schramm, MC Blum, D Link, S Klee, Acta Ophthalmologica 100, 2022

Neuronal sources of visually evoked potentials using selective color opponent channel stimulation. S Klee, D Link, Acta Ophthalmologica 100, 2022

Influence of pre‐adaptation time to background illumination on photopic negative response of the full‐field electroretinogram. MC Blum, S Klee, Acta Ophthalmologica 100, 2022

2021

3D retinal imaging and measurement using light field technology. S Schramm, A Dietzel, D Link, MC Blum, S Klee, Journal of Biomedical Optics 26 (12), 126002, 2021

Modulation of Human Intraocular Pressure Using a Pneumatic System. B Krauß, D Link, R Stodtmeister, E Nagel, W Vilser, S Klee, Translational Vision Science & Technology 10 (14), 4-4, 2021

Direct current stimulation of the entire visual pathway does not affect the full field electroretinogram MC Blum, L Leydolph, S Klee, Brain Stimulation: Basic, Translational, and Clinical Research in …, 2021

Influence of electric field orientation on the effect of ocular current stimulation using full field electroretinogram MC Blum, L Leydolph, S Klee, Current Directions in Biomedi-cal Engineering 7 (2), 167-170, 2021

Technical light-field setup for 3D imaging of the human nerve head validated with an eye model. S Schramm, A Dietzel, MC Blum, D Link, S Klee, Current Directions in Biomed-ical Engineering 7 (2), 433-436,         2021

Ocular direct current stimulation affects retinal ganglion cells. MC Blum, A Hunold, B Solf, S Klee, Scientific reports 11 (1), 1-9   , 2021

Automatic segmentation of skin cells in multiphoton data using multi-stage merging. P Prinke, J Haueisen, S Klee, MQ Rizqie, E Supriyanto, K König, ..., Scientific reports 11 (1), 1-19, 2021

Corrigendum: The influence of the stimulus design on the harmonic components of the steady-state visual evoked potential

B Solf, S Schramm, MC Blum, S Klee, Frontiers in human neuroscience 14, 644304, 2021

Routing of Cardiovascular and Respiratory Oscillations to the Retinal Vessels. S Rieger, S Klee, D Baumgarten, JOURNAL OF VASCULAR RESEARCH 58, 16-16, 2021

Effects of ocular direct current stimulation on full field electroretinogram. MC Blum, B Solf, A Hunold, S Klee, Frontiers in neuroscience, 49   4,2021

Relationship between breathing gas mixtures and retinal vessel regulation. S Klee, D Link, U Jaeger, Acta Ophthalmologica 99, 2021

Light‐field imaging for glaucoma diagnosis—reproducibility on one patient. A Dietzel, S Schramm, D Link, S Klee, Acta Ophthalmologica 99, 2021

Offset characteristic of transient and steady‐state flash visual evoked potentials. B Solf, MC Blum, S Klee, Acta Ophthalmologica 99, 2021

The effect of the stimulus eccentricity on the main component of the steady‐state visual evoked potential. B Solf, MC Blum, S Klee, Acta Ophthalmologica 99,2021

Photopic negative response during and after ocular direct current stimulation. MC Blum, B Solf, S Klee, Acta Ophthalmologica 99, 2021

Light‐Field imaging of the human optic nerve head at different wavelengths—a case study. S Schramm, A Dietzel, MC Blum, D Link, S Klee, Acta Ophthalmologica 99, 2021

Scatter measurement in the human eye based on a Shack‐Hartmann wavefront aberrometer with extended field of view. S Schramm, B Solf, S Klee, Acta Ophthal-mologica 99, 2021

Fundus image quality assessment for an eye model with cataract using adapted illumination patterns. D Link, S Klee, Acta Ophthalmologica 99, 2021

2020

The influence of the stimulus design on the harmonic components of the steady-state visual evoked potential. B Solf, S Schramm, MC Blum, S Klee, Frontiers in human neuroscience 14, 343,1,2020

The effects of an ocular direct electrical stimulation on pattern-reversal electroretinogram. MC Blum, A Hunold, B Solf, S Klee, Frontiers in neuroscience 14, 588, 3,2020

Pulsed Electrical Stimulation of the Human Eye Enhances Retinal Vessel Reaction to Flickering Light (vol 13, 371, 2019). S Freitag, A Hunold, M Klemm, S Klee, D Link, E Nagel, J Haueisen, FRONTIERS IN HUMAN NEUROSCIENCE 14,      2020

Corrigendum: pulsed electrical stimulation of the human eye enhances retinal vessel reaction to flickering light

S Freitag, A Hunold, M Klemm, S Klee, D Link, E Nagel, J Haueisen

Frontiers in Human Neuroscience 14, 167, 1, 2020

P44 Combination of a direct current stimulation of the eye and a simultaneous electroretinogram recording. MC Blum, S Klee, Clinical Neurophysiology 131 (4), e37, 2020

2019

Validation of a measurement setup for simultaneous ERG recording and ocular current stimulation. MC Blum, S Klee, Acta Ophthalmologica 97, 2019

The effect of stimulus contrast on the harmonic components of steady state visual evoked potentials. B Solf, S Klee, Acta Ophthalmologica 97   1, 2019

Effects of technical and biological factors on the dynamic vessel analysis. S Klee, Acta Ophthalmologica 97, 2019

Pulsed electrical stimulation of the human eye enhances retinal vessel reaction to flickering light. S Freitag, A Hunold, M Klemm, S Klee, D Link, E Nagel, J Haueisen, Frontiers in human neuroscience 13, 371, 7, 2019

Raspberry Pi controlled flicker stimulation in dynamic retinal vessel analysis.D Link, S Klee, Investigative Ophthalmology & Visual Science 60 (9), 5733-5733, 2019

The effect of different flicker contrasts on the Dynamic Vessel Analysis. S Klee, D Link, Investigative Ophthalmology & Visual Science 60 (9), 6081-6081, 2019

Amplitude changes in the electrophysiological response of retinal cells during simultaneous current stimulation. MC Blum, A Hunold, D Link, S Freitag, S Klee. Investigative Ophthalmology & Visual Science 60 (9), 2504-2504, 2019

Objective measurement of forward-scattered light in the human eye: An electrophysiological approach. B Solf, S Schramm, D Link, S Klee. Plos one 14 (4), e0214850,1, 2019

2018

Bleaching effects and fluorescence lifetime imaging ophthalmoscopy. M Klemm, L Sauer, S Klee, D Link, S Peters, M Hammer, D Schweitzer, ..., Biomedical Optics Express 10 (3), 1446-1461, 5, 2019

Scotoma Simulation in Healthy Subjects. S Klee, D Link, S Sinzinger, J Haueisen, Optometry and Vision Science 95 (12), 1120-1128, 2, 2018

Retinal vessel diameter variations and their correlation to arterial blood pressure. S Rieger, L Lüken, D Link, S Dutz, S Klee, D Baumgarten, Investigative Ophthalmology & Visual Science 59 (9), 3198-3198, 2018

Dark-adapted versus bleached state in fluorescence lifetime imaging ophthalmoscopy. M Klemm, L Sauer, S Klee, D Link, S Peters, M Hammer, D Schweitzer, ..., Investigative Ophthalmology & Visual Science 59 (9), 4661-4661, 2018

The effect of different rest periods on the Dynamic Vessel Analysis. S Klee, D Link, Investigative Ophthalmology & Visual Science 59 (9), 4696-4696 , 2018

Dynamic Vessel Analysis using surface-mount device LEDs as light source. D Link, S Rieger, S Klee, Investigative Ophthalmology & Visual Science 59 (9), 4695-4695, 2018

Experimental characterization and correlation of Mayer waves in retinal vessel diameter and arterial blood pressure. S Rieger, S Klee, D Baumgarten, Frontiers in physiology 9, 892